Individualized Analgesia After Adenotonsillectomy

Completed 280 enrolled Children's Hospital of Fudan University

RandomizedParallel-groupQuadruple-blindPrevention

Summary

A high incidence of respiratory morbidity after adenotonsillectomy is reported in children with obstructive sleep apnea syndrome (OSAS). So we designed a prospective, double-blind, randomized controlled study to determine the effects of individualized opioid analgesia compared with conventional opioid analgesia on respiratory morbidity after adenotonsillectomy in Children with OSAS.

Timeline

Start: 2016-11
Primary completion: 2017-02
Completion: 2017-02

Publications

Guo J, Zhuang P, Liu K, Wan Y, Wang X. Effects of an individualized analgesia protocol on the need for medical interventions after adenotonsillectomy in children: a randomized controlled trial. BMC Anesthesiol. 2021 Feb 8;21(1):41. doi: 10.1186/s12871-021-01263-3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Morphine	Other / unclassified	10 ug/kg	—
Subject	Morphine	Other / unclassified	50 ug/kg	—

Indications

No indication recorded.