drugset
drugset / Trial / NCT06630520

Intraoperative Periarticular Injection in Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery

NCT06630520 ↗

Completed 288 enrolled Taipei Veterans General Hospital, Taiwan
RandomizedParallel-groupDouble-blindTreatment

Summary

In this prospective, assessor-blinded, single-surgeon clinical trial, the goal was to validate the efficacy of PAI in aACLR surgery with a reduced opioid dose, while achieving similar pain relief with few adverse events. 300 patients who had undergone aACLR were randomly allocated to receive either a PAI or nPAI group. The primary outcome parameters were visual analogue scale (VAS) scores and cumulative morphine dose, through time. Secondary outcome parameters included drug-related adverse events.

Timeline

Start
2022-03-20
Primary completion
2022-06-20
Completion
2023-06-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 150 mg Other
Subject Ketorolac Other / unclassified 60 mg Other
Subject Morphine Other / unclassified 1 mg Other
Background Acetaminophen Small molecule 500 mg Oral
Background Diclofenac Other / unclassified 75 mg Oral

Indications

No indication recorded.