drugset / Trial / NCT01593397
Adiponectin Polymorphisms, Insulin Resistance, and Pharmacokinetics in Obesity
Phase 1
Completed
100 enrolled
Stanford University
National Institute of General Medical Sciences (NIGMS) · collab
NaSingle-groupOpen-labelDiagnostic
Summary
The primary objective of this study is to determine the influence of insulin resistance on drug metabolism and response in obese subjects. The investigators hypothesize that expression of adiponectin (a hormone secreted by fat tissue), and specific variants in the adiponectin gene can predict the insulin resistance and drug response among obese subjects.
Timeline
- Start
- 2011-11
- Primary completion
- 2017-09
- Completion
- 2017-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fentanyl | Other / unclassified | 2 ng/ml | Other |
| Subject | Propofol | Small molecule | 2 mg/kg | Other |