Memory & Conditioning Under Anesthesia

Phase 1 Completed 92 enrolled Keith M Vogt National Institute of General Medical Sciences (NIGMS) · collab

RandomizedParallel-groupSingle-blindBasic science

Summary

The purpose of this study is to determine the effects of pain on long-term memory and conditioned physiologic responses in the presence and absence of distinct intravenous anesthetics. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena The study will occur over 5 visits and involves no long-term follow up.

Timeline

Start: 2020-07-30
Primary completion: 2024-04-22
Completion: 2024-04-22

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexmedetomidine	Other / unclassified	0.15 ng/ml	Intravenous
Subject	Fentanyl	Other / unclassified	0.9 ng/ml	Intravenous
Subject	Propofol	Small molecule	0.7 ug/ml	Intravenous

Indications

No indication recorded.