Superficial, Cervical Block in Thyroid Surgery, a Randomized Controlled Trial

Summary

The study investigates the impact on post-operative pain of the superficial cervical block with bupivacaine combined with subcutaneous infiltration of the incisional area in thyroid surgery under general anesthesia. In addition, cost savings using the cervical block are evaluated (due to reduced length of hospital stay). The study is prospective, randomized, double blind, and placebo-controlled. The study is performed at the Department of Surgery, Cantonal Hospital of St. Gallen.

Timeline

Start

2006-01

Primary completion

2008-12

Completion

2008-12

Outcome

Met primary endpoint

paper The bupivacaine group had significantly less pain than the placebo group (P = 0.016). PMID 20632263 ↗

registry analysis (superiority or other test); Cervivcal Block Before Surgery vs Cervivcal Block After Surgery vs Placebo Cervivcal Block Before Surgery vs Placebo Cervivcal Block After Surgery; p = .028; t-test, 2 sided NCT00472446 ↗

Publications

• Results Steffen T, Warschkow R, Brandle M, Tarantino I, Clerici T. Randomized controlled trial of bilateral superficial cervical plexus block versus placebo in thyroid surgery. Br J Surg. 2010 Jul;97(7):1000-6. doi: 10.1002/bjs.7077.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	5 %	Subcutaneous
Subject	Bupivacaine	Other / unclassified	10 ml	Subcutaneous

Indications

No indication recorded.