drugset / Trial / NCT02752971

Wound Infiltration With Sodium Diclofenac vs Bupivacaine for Postoperative Pain Following Appendectomy

NCT02752971

Phase 3 Completed 43 enrolled Hospital Central Dr. Luis Ortega
RandomizedCrossoverTriple-blindTreatment

Summary

The infiltration of the surgical wound is an effective strategy for postoperative analgesia. Nonsteroidal antiinflammatories are useful in this way. Objective: To compare the analgesic effectiveness of diclofenac sodium, bupivacaine or bupivacaine plus diclofenac sodium infiltrating wound appendectomies. Method: Comparative, double blind, American Society Anesthesiologist classification I-II,18-65años. Group 1 (Bupivacaine n = 14), Group 2 (Diclofenac Sodium n = 14), Group 3 (Bupivacaine + Diclofenac Sodium n = 15). Pain at rest and dynamic, rescue analgesic consumption in Post Anesthesia Care Unit (PACU) and 24 hours after surgery were evaluated.

Timeline

Start
2015-02
Primary completion
2016-02
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 0.25 % Other
Subject Bupivacaine Other / unclassified 15 ml Other
Subject Diclofenac Other / unclassified 3 ml Other
Subject Diclofenac Other / unclassified 75 mg Other

Indications

No indication recorded.