Nebulized Bupivacaine Analgesia for Cleft Palate Repair

Phase 3 Recruiting 60 enrolled Assiut University

RandomizedParallel-groupDouble-blindTreatment

Summary

In this study we introduce a potent local anesthetic; bupivacaine 0.5% in 0.5 mg/kg dose by nebulization as a preemptive analgesia to compare efficacy and safety in children with cleft palate repair.

Timeline

Start: 2021-06-14
Primary completion: 2026-08-10
Completion: 2026-09-20

Publications

Results Chiono J, Raux O, Bringuier S, Sola C, Bigorre M, Capdevila X, Dadure C. Bilateral suprazygomatic maxillary nerve block for cleft palate repair in children: a prospective, randomized, double-blind study versus placebo. Anesthesiology. 2014 Jun;120(6):1362-9. doi: 10.1097/ALN.0000000000000171.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	0.5 %	Inhaled
Subject	Bupivacaine	Other / unclassified	0.5 mg/kg	Inhaled

Nebulized Bupivacaine Analgesia for Cleft Palate Repair

Summary

Timeline

Publications

Drugs

Indications