drugset / Trial / NCT05734625
Efficacy of Nerve Blocks for Episodic Migraine
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to see how well blocking two to ten of the scalp nerves (that give feeling to the scalp and are painful during migraine headaches) with bupivacaine anesthetic (numbing medication) and low dose methylprednisolone (cortisone-like medicine or steroid) work for treating and preventing migraines. Our hypothesis is that the pain of most episodic migraine headaches can be eliminated and prevented for months by blocking the nerves that give pain sensation during a migraine.
Timeline
- Start
- 2023-07-10
- Primary completion
- 2027-02
- Completion
- 2027-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 0.5 ml | Other |
| Subject | Bupivacaine | Other / unclassified | 1 ml | Other |
| Subject | Bupivacaine | Other / unclassified | 1.25 ml | Other |
| Subject | Methylprednisolone | Other / unclassified | 10 mg | Other |
| Subject | Methylprednisolone | Other / unclassified | 20 mg | Other |