Comparison Between Dexamethasone and Dexmedetomidine in Spinal Anesthesia for Cases With Fracture Pelvis Fixation

Phase 0 Active not recruiting 60 enrolled Sohag University

RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study is to compare dexamethasone and dexmedetomidine as adjuvant to bupivacaine in fracture pelvis fixation as regard duration of sensory block and postoperative pain management.

Timeline

Start: 2026-02-08
Primary completion: 2026-08-31
Completion: 2026-08-31

Publications

Background Tang, P., Chen, H., Zhao, Z. and Wu, Y.(2023). Pelvic fractures. Orthopaedic Trauma Surgery: Volume 3: Axial Skeleton Fractures and Nonunion: Springer; 2023. p. 73-130.
Background Meyhoff CS, Thomsen CH, Rasmussen LS, Nielsen PR. High incidence of chronic pain following surgery for pelvic fracture. Clin J Pain. 2006 Feb;22(2):167-72. doi: 10.1097/01.ajp.0000174266.12831.a2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexamethasone	Small molecule	4 mg	Intrathecal
Comparator	Dexmedetomidine	Other / unclassified	4 mg	Intrathecal
Comparator	Bupivacaine	Other / unclassified	13 mg	Intrathecal

Indications

No indication recorded.