drugset / Trial / NCT07842159

Long-acting Local Vaginal Cuff Anesthesia Following Hysterectomy

NCT07842159 ↗

Phase 1/2 Not yet recruiting 104 enrolled The University of Texas Health Science Center, Houston
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to compare recovery unit and post operation day (POD) 1 pain score in women following elective robotic assisted TLH (RA-TLH) for benign indication with and without local vaginal cuff injection of short acting bupivacaine and long acting Exparel, to evaluate postoperative pain management and control by assessing the amount and frequency of NSAIDS and opioids taken and to assess bleeding, vaginal discharge and or vaginal dehiscence at the postoperative follow up visit.

Timeline

Start
2026-09-17
Primary completion
2028-03-17
Completion
2028-09-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 0.25 % Other
Subject Bupivacaine Other / unclassified 266 mg Other

Indications

No indication recorded.