drugset / Trial / NCT02616367

Comparison of Comparison of Ropivacaine and Liposomal Bupivacaine for Total Knee Arthroplasty

NCT02616367

Phase 2 Withdrawn University of Minnesota
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a randomized prospective outcomes study comparing two groups of patients. One group will receive liposomal bupivacaine for a periarticular injection. The other will receive ropivacaine for periarticular injection for pain relief after Total Knee Arthroplasty. the primary objective of this study is to determine if liposomal bupivacaine provides superior pain control (decreased maximal pain scores within the first 72 hours post surgery) when compared to ropivacaine when injected in a periarticular injection.

Timeline

Start
2015-12
Primary completion
2016-12
Completion
2017-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 20 ml Other
Comparator Ropivacaine Other / unclassified 200 mg Other

Indications