drugset / Trial / NCT03762343

Ultrasound-guided Greater Occipital Nerve Block in Children Undergoing Posterior Fossa Craniotomy

NCT03762343

Phase 3 Completed 40 enrolled Kasr El Aini Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

Surgery within the posterior fossa is associated with the highest incidence and greatest severity of acute postoperative pain that may persist beyond the immediate postoperative period. The utilization of local nerve blocks of the scalp in children may provide analgesia with stable hemodynamics while reducing the need for other anesthetics such as inhaled anesthetics and opioids. This could in turn result in less side effects, higher patient and family satisfaction, and better outcomes. The use of ultrasound-guided greater occipital nerve block (GONB) for perioperative pain management of posterior fossa surgery in pediatrics is not previously reported.

Timeline

Start
2019-01-01
Primary completion
2020-12-01
Completion
2020-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 2 ml Subcutaneous
Comparator Acetaminophen Small molecule 15 mg/kg Intravenous
Comparator Fentanyl Other / unclassified 0.5 ug/kg Intravenous
Comparator Fentanyl Other / unclassified 2 ug/kg Intravenous