Drugs / Lidocaine
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Lidocaine

English name lidocaine

Other / unclassified targets GOLT1A, TLR4, TRPV1 via inhibition / activation

Developed for
neuropathy, painful · chronic pain syndrome · migraine disorder · interstitial cystitis · osteoarthritis, knee · colorectal cancer · headache disorder · carpal tunnel syndrome
+213 more · myofascial pain syndrome · pulpitis · female infertility · postherpetic neuralgia · hemorrhoid · rotator cuff syndrome · breast cancer · gastroesophageal reflux disease · pharyngitis · tinnitus · arthropathy · cancer · cataract · colon carcinoma · delirium · fibromyalgia · overactive bladder · pregnancy disorder · spinal cord injury · stroke disorder · trigeminal neuralgia · anxiety · cardiac rhythm disease · female reproductive system disorder · head and neck cancer · ileus · infertility disorder · intracranial hypotension · malignant pancreatic neoplasm · morbid obesity · obstetric disorder · pelvis syndrome · prostate cancer · shoulder impingement syndrome · temporomandibular joint disorder · tendinitis · thyroid cancer · uterine inflammatory disease · vulvodynia · acquired aneurysmal subarachnoid hemorrhage · acute lung injury · adolescent idiopathic scoliosis · anterior cutaneous nerve entrapment syndrome · articular cartilage disorder · autism · bursitis · cerebrovascular disorder · cholelithiasis · chronic ulcer of skin · colorectal neoplasm · constipation disorder · COVID-19 · cranial nerve palsy · dental pulp disorder · diabetes mellitus · diabetic neuropathy · endometriosis · frozen shoulder · herpes zoster · impacted teeth, multiple · intermediate coronary syndrome · leiomyoma · lumbar disk disease · musculoskeletal system disorder · obstructive sleep apnea syndrome · Parkinson disease · peripheral nerve lesion · premature ejaculation · radiculopathy · sickle cell disease · strabismus · traumatic brain injury · traumatic encephalopathy · ulcer of lower limbs · ureterolithiasis · urinary tract obstruction · uterine disorder · vertebral column disorder · abscess · acute opioid poisoning · acute respiratory distress syndrome · adult acute respiratory distress syndrome · allesthesia · atrial fibrillation · bacterial vaginosis · Barre-Lieou syndrome · bowel dysfunction · brain aneurysm · breast carcinoma · breast disorder · central centrifugal cicatricial alopecia · cerebral palsy · cervical cancer · chemotherapy-induced neuropathy · chemotherapy-induced oral mucositis · chronic pancreatitis · cocaine dependence · cognitive disorder · common cold · complex regional pain syndrome · curariform drugs toxicity · dementia · diabetic polyneuropathy · digestive system disorder · disease of the tendon · dysmenorrhea · ecthyma · esophagitis · female breast carcinoma · glioblastoma · heart failure · hepatocellular carcinoma · hernia, double inguinal · hiatus hernia · hypertensive disorder · infectious neuropathy · inflammatory disease · insect Stings, hypersensitivity to · irritable bowel syndrome · ischemic disease · ischemic stroke · metastatic malignant neoplasm · migraine with aura · migraine without aura · Morton neuroma · mucositis · nephrolithiasis · non-small cell lung carcinoma · oropharynx squamous cell carcinoma · osteoarthritis · osteoarthritis, hand · otitis media · otorhinolaryngologic disease · pain agnosia · palmoplantar keratosis · pancreatitis · parkinsonian disorder · pelvic organ prolapse · periarthritis · periodontitis · plantar fasciitis · post-surgical hypoinsulinemia · pregnancy disorder with abortive outcome · proliferative diabetic retinopathy · pudendal neuralgia · pulmonary edema · radiation-induced neuropathy · restless legs syndrome · retinal detachment · sciatica · scorpion envenomation · sensory peripheral neuropathy · sleep disorder · small intestine disorder · spondylosis, cervical · stomatitis · subarachnoid hemorrhage · syncope, familial vasovagal · systemic sclerosis · temporomandibular joint dysfunction syndrome · thalassemia · tonsillitis · tooth disorder · trichomonal vulvovaginitis · ulcerative stomatitis · urethral disorder · urinary bladder disorder · vulvar disease · vulvovaginal candidiasis · acute stress disorder · anal fistula · ankylosing spondylitis · anxiety disorder · arthritic joint disease · cardiac arrest · cardiac valvular defect · clubfoot · complex regional pain syndrome type 1 · congenital deformities of limbs · coronary vasospasm · developmental dysplasia of the hip · epicondylitis · gallstones · hyperhidrosis palmaris ET plantaris · infectious discitis · intervertebral disk degenerative disorder · kidney cancer · large intestine disorder · laryngeal disorder · myopathy, congenital, with respiratory insufficiency and bone fractures · nasal disorder · neuroma · osteoarthritis, hip · pancreas disorder · peripheral neuropathy · persistent idiopathic facial pain · pilonidal sinus · piriformis syndrome · postoperative ventricular dysfunction · preeclampsia · pterygium · radiculitis · refractory malignant neoplasm · scoliosis · sexual disorder · spinal stenosis · subacute delirium · tendinosis · tenosynovitis · toe, misshapen · upper respiratory tract disorder · urinary system disorder · urolithiasis
Investigated by
Cairo University · Assiut University · Endo USA Inc., a Keenova Therapeutics Company · ZARS Pharma Inc. · Ain Shams University · Yonsei University
+669 more · Scilex Pharmaceuticals, Inc. · Tanta University · Washington University School of Medicine · West China Hospital · Copka Sonpashan · General Hospital of Ningxia Medical University · Muhammad · Aalborg University · Allergan · Ankara City Hospital Bilkent · Aswan University Hospital · Duke University · Stanford University · The Catholic University of Korea · University of California, San Diego · University of California, San Francisco · Federal University of São Paulo · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Mayo Clinic · McMaster University · Medical University of Silesia · Oregon Health and Science University · The University of Texas Health Science Center, Houston · University of British Columbia · University of Campinas, Brazil · University of Sao Paulo · Anqing Municipal Hospital · Beijing Tiantan Hospital · Dr. Lutfi Kirdar Kartal Training and Research Hospital · Grünenthal GmbH · Johns Hopkins University · Medical University of Warsaw · National Taiwan University Hospital · Northwestern University · Ohio State University · Rigshospitalet, Denmark · Rutgers, The State University of New Jersey · Taris Biomedical LLC · The Cleveland Clinic · University of Alabama at Birmingham · University of North Carolina, Chapel Hill · University of Saskatchewan · Aarhus University Hospital · Ahmadu Bello University Teaching Hospital · Ajou University School of Medicine · AlgoRx Pharmaceuticals · Assistance Publique - Hôpitaux de Paris · Ataturk University · Brigham and Women's Hospital · Dow University of Health Sciences · Hamilton Health Sciences Corporation · Hopital Foch · Hospices Civils de Lyon · Isifer AB · Jamia Millia Islamia · Kaohsiung Medical University Chung-Ho Memorial Hospital · Kasr El Aini Hospital · Khon Kaen University · Loma Linda University · Mahidol University · Milton S. Hershey Medical Center · NYU Langone Health · National Cancer Institute (NCI) · Nordsjaellands Hospital · Northwell Health · Nuvo Research Inc. · Rennes University Hospital · Seoul National University Hospital · Shandong University · Silesian University of Medicine · Society of Family Planning · São Paulo Research Foundation · Universiti Kebangsaan Malaysia Medical Centre · University Health Network, Toronto · all 675 on the full record

Regulatory milestones approvals, filings & regulatory actions · 6 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) ZTLIDO 2021-04-08 fda.gov
Approved EU (EMA) Fortacin 2013-11-15 europa.eu
Label expansion US (FDA) ZINGO 2009-01-08 fda.gov
Label expansion US (FDA) XYLOCAINE 1981-02-23 fda.gov
Label expansion US (FDA) LIDOPEN 1976-10-18 fda.gov
Approved US (FDA) XYLOCAINE DENTAL 1948-11-19 fda.gov

Trials 916 · started per year

today
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EU approved 2013
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 025 trials
Phase 0 NCT07709390 Jun 2026 → Jan 2029 expected Ohio State University Not yet recruiting No outcome recorded
Phase 0 NCT07707557 Dec 2025 → Jun 2026 overdue Abbasi Shaheed Hospital Active not recruiting No outcome recorded
Phase 0 NCT06935552 Jun 2025 → Nov 2026 expected Assiut University Not yet recruiting No outcome recorded
Phase 0 NCT06462573 Sep 2024 → Sep 2026 expected ureterolithiasis Assiut University Not yet recruiting No outcome recorded
Phase 0 NCT06243120 Mar → Sep 2024 Ain Shams University Unknown No outcome recorded
Phase 0 NCT07169032 Jan → Feb 2024 Li Zhen Zhong Completed No outcome recorded
Phase 0 NCT05298761 Dec 2023 → Mar 2024 Sheikh Zayed Medical College Unknown No outcome recorded
Phase 0 NCT03095404 Oct 2022 → Aug 2025 McMaster University Withdrawn No outcome recorded
Phase 0 NCT05921292 Jul 2022 → Jan 2024 chronic ulcer of skin Omeza, LLC Completed No outcome recorded
Phase 0 NCT06293807 Jun 2022 → Apr 2023 periodontal disorder The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 151 trials
Phase 1 NCT06747390 Apr 2025 → Nov 2026 expected human papilloma virus infection, oropharynx squamous cell carcinoma Ryan Carey Recruiting No outcome recorded
Phase 1 NCT06310200 Jan → May 2025 overdue headache disorder Wright State University Active not recruiting No outcome recorded
Phase 1 NCT06462781 Mar 2024 → May 2025 migraine disorder The Cooper Health System Completed No outcome recorded
Phase 1 NCT06516861 Jan → Feb 2024 Arsil Radiansyah Completed No outcome recorded
Phase 1 NCT05501600 Nov 2022 → Nov 2023 Keith M Vogt Completed No outcome recorded
Phase 1 NCT05417425 Sep 2022 → Oct 2023 ulcer of lower limbs Omeza, LLC Completed No outcome recorded
Phase 1 NCT05343299 May 2022 → Jun 2023 Nîmes University Hospital Completed No outcome recorded
Phase 1 NCT05361369 May 2022 Exeltis Turkey Completed No outcome recorded
Phase 1 NCT04941040 Jul → Oct 2021 supratentorial cancer Kasr El Aini Hospital Completed No outcome recorded
Phase 1 NCT05106400 Jul 2021 Scilex Pharmaceuticals, Inc. Completed No outcome recorded
Phase 1/213 trials
Phase 1/2 NCT06875791 Dec 2025 → Dec 2026 expected head and neck squamous cell carcinoma, mucositis Fundacion Clinica Valle del Lili Not yet recruiting No outcome recorded
Phase 1/2 NCT05694858 Feb 2025 → Dec 2026 expected cataract, glaucoma Universiti Kebangsaan Malaysia Medical Centre Recruiting No outcome recorded
Phase 1/2 NCT06661902 Jan 2025 → Jan 2026 prostate cancer University of Washington Completed No outcome recorded
Phase 1/2 NCT05573191 Oct → Nov 2022 General Hospital of Ningxia Medical University Unknown No outcome recorded
Phase 1/2 NCT05476679 Sep 2022 → Jun 2023 Raziel Therapeutics Ltd. Completed No outcome recorded
Phase 1/2 NCT04026945 Oct 2019 → Mar 2021 chronic pain syndrome University of British Columbia Completed No outcome recorded
Phase 1/2 NCT03220113 Jul 2017 → Jul 2018 migraine with aura, migraine without aura Corona Doctors Medical Clinics, Inc. Unknown No outcome recorded
Phase 1/2 NCT01654302 Sep 2013 → Sep 2014 osteoarthritis, knee Thomas J. Schnitzer Completed No outcome recorded
Phase 1/2 NCT03117166 Jan → May 2010 Drexel University College of Medicine Terminated No outcome recorded
Phase 1/2 NCT00791024 Nov 2008 → Nov 2009 Ove Andersen Completed No outcome recorded
Phase 295 trials
Phase 2 NCT04414917 Nov 2026 → Nov 2029 neuropathy, painful Rutgers, The State University of New Jersey Suspended No outcome recorded
Phase 2 NCT07094542 Sep 2026 → Nov 2029 expected impacted teeth, multiple, myofascial pain syndrome Rutgers, The State University of New Jersey Not yet recruiting No outcome recorded
Phase 2 NCT07700108 Jun 2026 → Jan 2029 expected Ohio State University Recruiting No outcome recorded
Phase 2 NCT07054801 Jun 2026 → Jan 2027 expected subarachnoid hemorrhage Daniel Raper, MBBS Recruiting No outcome recorded
Phase 2 NCT07567274 May → Jul 2026 overdue tinnitus Leading Edge Clinic Enrolling by invitation No outcome recorded
Phase 2 NCT07268118 May 2026 → Jun 2027 expected Beth Israel Deaconess Medical Center Recruiting No outcome recorded
Phase 2 NCT05729503 May 2026 anxiety University of Calgary Withdrawn No outcome recorded
Phase 2 NCT07361549 Mar 2026 → Dec 2030 expected migraine disorder The Cooper Health System Not yet recruiting No outcome recorded
Phase 2 NCT07273916 Mar → May 2026 overdue Hexsel Dermatology Clinic Not yet recruiting No outcome recorded
Phase 2 NCT07294118 Jan 2026 → Jun 2027 expected acquired aneurysmal subarachnoid hemorrhage, headache disorder, opiate dependence The University of Texas Medical Branch, Galveston Recruiting No outcome recorded
Phase 2/324 trials
Phase 2/3 NCT07445191 Mar → Jun 2026 overdue temporomandibular joint disorder Cairo University Not yet recruiting No outcome recorded
Phase 2/3 NCT07315490 Aug 2025 → Jan 2026 overdue PAEC General Hospital, Islamabad Active not recruiting No outcome recorded
Phase 2/3 NCT07343128 Jun → Dec 2025 fibromyalgia Sanliurfa Education and Research Hospital Completed No outcome recorded
Phase 2/3 NCT06740903 Aug 2024 → Aug 2025 overdue cholecystitis Sahiwal medical college sahiwal Recruiting No outcome recorded
Phase 2/3 NCT03226626 Dec 2021 → Jan 2022 infectious disease with sepsis, thrombotic disease HK Surgical, Inc. Unknown No outcome recorded
Phase 2/3 NCT05153785 Nov 2021 → Jun 2025 liver cancer, substance-related disorder Lund University Hospital Completed No outcome recorded
Phase 2/3 NCT04648891 Aug 2021 → Jul 2023 spasmodic dystonia Mayo Clinic Completed No outcome recorded
Phase 2/3 NCT04741880 Jun 2021 → Dec 2022 cancer Brazilian National Cancer Institute Unknown No outcome recorded
Phase 2/3 NCT04901065 May → Jun 2021 COVID-19 Evelyne D.Trottier Completed No outcome recorded
Phase 2/3 NCT03967197 Aug 2019 → Aug 2020 University of Montreal Hospital Centre (CHUM) Completed No outcome recorded
Phase 3117 trials
Phase 3 NCT07274254 Jul 2026 → Aug 2028 expected sickle cell disease Nantes University Hospital Recruiting No outcome recorded
Phase 3 NCT07661758 Jul → Nov 2026 expected headache disorder Tanta University Recruiting No outcome recorded
Phase 3 NCT07076641 Jul 2026 → Jul 2027 expected digestive system disorder Ramsay Santé Not yet recruiting No outcome recorded
Phase 3 NCT07414706 Mar 2026 → Jun 2028 expected local anesthetic poisoning Centre Hospitalier Universitaire, Amiens Not yet recruiting No outcome recorded
Phase 3 NCT07330726 Jan → Apr 2026 overdue impacted teeth, multiple Fayoum University Not yet recruiting No outcome recorded
Phase 3 NCT07299630 Dec 2025 → May 2026 Ain Shams University Completed No outcome recorded
Phase 3 NCT07212192 Nov → Dec 2025 overdue pregnancy disorder Phenikaa University Not yet recruiting No outcome recorded
Phase 3 NCT07000760 Jun 2025 → Jan 2026 Jun Zhang Completed No outcome recorded
Phase 3 NCT06769204 Feb → Aug 2025 overdue female infertility Cairo University Not yet recruiting No outcome recorded
Phase 3 NCT06202989 Sep 2024 → May 2026 KAZM Pharmaceuticals Inc. Completed No outcome recorded
Show all 117 trials opens the full record — a long page
Phase 4237 trials
Phase 4 NCT07566312 Jan → Apr 2027 expected Duke University Not yet recruiting No outcome recorded
Phase 4 NCT07429292 Sep → Dec 2026 expected Duke University Not yet recruiting No outcome recorded
Phase 4 NCT07497737 Aug 2026 → Apr 2027 expected frozen shoulder University Hospitals Cleveland Medical Center Not yet recruiting No outcome recorded
Phase 4 NCT07590830 Aug 2026 → Sep 2028 expected Rennes University Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07691359 Jul 2026 → Oct 2027 expected neuropathy, painful, osteoporosis University Hospital, Clermont-Ferrand Not yet recruiting No outcome recorded
Phase 4 NCT07552766 Jun 2026 → Dec 2028 expected Nemours Children's Clinic Recruiting No outcome recorded
Phase 4 NCT07354217 Jun 2026 → Dec 2030 expected paroxysmal atrial fibrillation National Taiwan University Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07601698 May → Nov 2026 expected Sohag University Not yet recruiting No outcome recorded
Phase 4 NCT07504497 Apr → Dec 2026 expected Younes Ahmed Younes Not yet recruiting No outcome recorded
Phase 4 NCT07499154 Apr 2026 → Dec 2027 expected acute lung injury, congenital heart disease The Children's Hospital of Zhejiang University School of Medicine Not yet recruiting No outcome recorded
Show all 237 trials opens the full record — a long page
Phase not applicable354 trials
NCT07627100 Jun 2026 → Jun 2027 expected Mayo Hospital Lahore Not yet recruiting No outcome recorded
NCT07657260 Jun → Jul 2026 overdue Xidian University Recruiting No outcome recorded
NCT07612839 Jun → Aug 2026 overdue Hakan Emirkadı Not yet recruiting No outcome recorded
NCT07607691 Jun → Oct 2026 expected bursitis, chronic pain syndrome, frozen shoulder, rotator cuff syndrome Ankara City Hospital Bilkent Not yet recruiting No outcome recorded
NCT07675616 May → Dec 2026 expected lacrimal duct obstruction Cairo University Recruiting No outcome recorded
NCT07203274 May → Dec 2026 expected Aalborg University Not yet recruiting No outcome recorded
NCT07488832 Apr → Nov 2026 expected Ankara City Hospital Bilkent Recruiting No outcome recorded
NCT07267897 Mar → Jun 2026 overdue Sakarya University Not yet recruiting No outcome recorded
NCT07638254 Mar → Sep 2026 expected pulpitis Autonomous University of San Luis Potosí Recruiting No outcome recorded
NCT07703553 Feb → Jul 2026 Harran University Completed No outcome recorded
Show all 354 trials opens the full record — a long page
Also used as a comparator or background therapy in 1,085 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 039 trials
Phase 0 NCT06999057 Comparator Aug 2026 → Aug 2027 expected University of Central Florida Recruiting No outcome recorded
Phase 0 NCT07211399 Background Jul 2026 → Dec 2030 substance-related disorder Jacques E. Chelly Withdrawn No outcome recorded
Phase 0 NCT07675304 Comparator May → Dec 2026 expected National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland Recruiting No outcome recorded
Phase 0 NCT07511400 Comparator Apr → Jun 2026 Medical University of Vienna Completed No outcome recorded
Phase 0 NCT07408193 Comparator Mar 2026 → Aug 2027 expected refractory malignant neoplasm National and Kapodistrian University of Athens Recruiting No outcome recorded
Phase 138 trials
Phase 1 NCT06653400 Background Feb 2025 → Sep 2026 expected pain agnosia, uterine anomalies Icahn School of Medicine at Mount Sinai Recruiting No outcome recorded
Phase 1 NCT06834854 Comparator Mar → Aug 2024 Ain Shams University Completed No outcome recorded
Phase 1 NCT07248332 Comparator Jan 2024 → Sep 2025 acute cholecystitis Liaquat National Hospital & Medical College Completed No outcome recorded
Phase 1 NCT06564987 Comparator Jan → Dec 2024 overdue Cleveland Dental Institute Recruiting No outcome recorded
Phase 1 NCT06631625 Background Sep 2023 → Sep 2024 Alexandria University Completed No outcome recorded
Phase 1/225 trials
Phase 1/2 NCT07396129 Comparator Aug → Dec 2026 expected neuropathy, painful Pontificia Universidad Catolica de Chile Not yet recruiting No outcome recorded
Phase 1/2 NCT07256834 Comparator Nov → Dec 2025 overdue Jinnah Postgraduate Medical Centre Not yet recruiting No outcome recorded
Phase 1/2 NCT06983886 Background May 2025 → Jun 2026 overdue Ramathibodi Hospital Not yet recruiting No outcome recorded
Phase 1/2 NCT06820164 Background May 2025 → Jan 2027 expected lipoma West Virginia University Recruiting No outcome recorded
Phase 1/2 NCT06431165 Comparator Mar 2024 → Mar 2025 Cairo University Unknown No outcome recorded
Phase 290 trials
Phase 2 NCT07068243 Background Sep 2026 → Feb 2027 expected Duke University Not yet recruiting No outcome recorded
Phase 2 NCT07487246 Background Jun 2026 → Apr 2027 expected Rush University Medical Center Recruiting No outcome recorded
Phase 2 NCT07680504 Background Jun 2026 → Jun 2029 expected frozen shoulder Nantes University Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06923787 Comparator Feb 2026 → Jul 2027 expected colon carcinoma Institute of Oncology Ljubljana Recruiting No outcome recorded
Phase 2 NCT04707183 Comparator May 2025 → May 2026 Stanford University Withdrawn No outcome recorded
Phase 2/339 trials
Phase 2/3 NCT07150481 Comparator Oct 2025 → Dec 2026 expected Assiut University Not yet recruiting No outcome recorded
Phase 2/3 NCT07000058 Comparator Jun → Dec 2025 overdue Misr University for Science and Technology Active not recruiting No outcome recorded
Phase 2/3 NCT07062497 Background Jan → Dec 2025 overdue abdominal wall malformation Federal University of Rio de Janeiro Recruiting No outcome recorded
Phase 2/3 NCT06427707 Comparator Jun → Oct 2024 overdue esophageal varices with bleeding Ain Shams University Recruiting No outcome recorded
Phase 2/3 NCT06266481 Comparator Mar → Apr 2024 Pharos University in Alexandria Unknown No outcome recorded
Phase 3106 trials
Phase 3 NCT07672236 Comparator Jul → Dec 2026 expected head and neck cancer, mucositis OncoZenge AB Recruiting No outcome recorded
Phase 3 NCT07592143 Background Jul → Dec 2026 expected King Edward Medical University Not yet recruiting No outcome recorded
Phase 3 NCT04990128 Comparator Jun 2026 → Jul 2027 expected osteoarthritis, hip The Cleveland Clinic Not yet recruiting No outcome recorded
Phase 3 NCT07650396 Comparator Jun 2026 → Dec 2027 expected disease of the tendon Erasmus Medical Center Recruiting No outcome recorded
Phase 3 NCT05279937 Comparator Jun 2026 → Jun 2027 expected Ehlers-Danlos syndrome Tulane University Not yet recruiting No outcome recorded
Show all 106 trials opens the full record — a long page
Phase 4319 trials
Phase 4 NCT07273006 Comparator Sep 2026 → Nov 2028 expected arthropathy Universidad Complutense de Madrid Not yet recruiting No outcome recorded
Phase 4 NCT07644923 Background Aug 2026 → Aug 2028 expected NYU Langone Health Not yet recruiting No outcome recorded
Phase 4 NCT06792474 Comparator Aug 2026 → Aug 2027 expected vertebral column disorder Dartmouth-Hitchcock Medical Center Not yet recruiting No outcome recorded
Phase 4 NCT07430085 Comparator Jul 2026 → Jan 2028 expected osteoarthritis, knee Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) Not yet recruiting No outcome recorded
Phase 4 NCT07224711 Comparator Jul 2026 → May 2028 expected Vanderbilt University Medical Center Not yet recruiting No outcome recorded
Show all 319 trials opens the full record — a long page
Phase not applicable429 trials
NCT07624890 Comparator Dec 2026 expected neuroma Ukrainian Society of Regional Anesthesia and Pain Therapy Not yet recruiting No outcome recorded
NCT07509918 Comparator Sep → Oct 2026 expected Cairo University Not yet recruiting No outcome recorded
NCT07630155 Background Aug 2026 → Aug 2027 expected renal pelvis/ureter urothelial carcinoma University of Michigan Rogel Cancer Center Recruiting No outcome recorded
NCT07665463 Background Jul → Dec 2026 expected Jagiellonian University Not yet recruiting No outcome recorded
NCT07687290 Comparator Jun → Dec 2026 expected Ain Shams University Recruiting No outcome recorded
Show all 429 trials opens the full record — a long page

Evidence & citations 114 cited values

Every value below carries the sentence it was read from. 2,011 sources stand behind the page.

FieldValueCited text
Known as lidocaine “The drug: 5% lidocaine ointment, a local anesthetic, will be applied to the end of a device: long channeled cotton tipped applicator inserted into both nares and placed over...” NCT03112720
1803

“A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in...” NCT01506154

“Participants will be induced using lidocaine 1 mg/kg IV, an opioid such a fentanyl (1-2 mcg/kg) IV, followed by 0.6 mg/kg IV rocuronium, and IV propofol with dosage at the...” NCT06029049

“Subjects in Group 2 (corticosteroid control) will receive a single ultrasound-guided intratendinous injection approximately (may be limited by tendon/soft tissue limitations of...” NCT03072381

“all of the patients of the experimental Celestone group will receive transforaminal epidural injection of the solution of 1 cc of Lidocaine 1% with 1 cc of Celestone®...” NCT02930057

“Participants will receive one ultrasound-guided injection with 1 ml Kenalog 40mg/ml and 1 ml Lidocaine 10mg/ml superficial to the insertion of the gluteus medius and minimus...” NCT06456099

“Ultrasound-guided injection of lyophilized platelet (30ng)+1.0 mL 1.0% Lidocaine+1.0 mL (10.0 mg/mL) Triamcinolone acetonide into the hypoechoic area of common extensor tendon...” NCT05648032

“General anesthesia without intraoperative opioids using dexmedetomidine, ketamine, lidocaine, sevoflurane, non-opioid co-analgesics, procedure-specific regional analgesia, and...” NCT07665463

“ALGRX 3268 (previously known as PowderJect® Dermal Lidocaine) is a system for needle-free, pain-free epidermal injection of lidocaine powder that provides local anesthesia...” NCT00132405

“Intra-articular injection with 25% dextrose will be carried out with the following details: 5 mL of 40% dextrose, 2 mL of lidocaine, and 1 mL of aqua dest are inserted into the...” NCT04557943

“Bladder instillation mixture of heparin (10,000 units), 2% viscous lidocaine (10 mL), 8.4% sodium bicarbonate (15 mL of 1 mEq/mL), 0.5% bupivacaine (10 mL of 5 mg/mL) plus...” NCT03463915

“Patients in the Lidocaine group received 3 mL of 2% lidocaine, diluted with 7 mL of normal saline to prepare a 10 mL solution, which was administered intravenously as a stat...” NCT07248384

“Patients in the Lidocaine group received 3 mL of 2% lidocaine, diluted with 7 mL of normal saline to prepare a 10 mL solution, which was administered intravenously as a stat...” NCT07248332

“EMLA Cream (Eutectic Mixture of Local Anesthetics) is an FDA-approved topical anesthetic comprised of 2.5% each of lidocaine/prilocaine. EMLA Cream was applied in approximately...” NCT00444626

“Comparison of the Effects of Intravenous Administration of Dexmedetomidine 0.5 μg/kg Body Weight With Intravenous Lidocaine 1.5 mg/kg Body Weight on Blood Pressure and Heart...” NCT06573957

“the intervention group (BRA-CLO) will receive bilateral RSB with a solution containing 8 mL of lidocaine 2%, 8 mL of ropivacaine 1%, and clonidine 75 mcg, diluted in 0.9%...” NCT07062497

“Thoracic epidural anesthesia (TEA), the infusion of anesthetic agents (eg, lidocaine or ropivacaine) into the epidural space, is used to achieve sympathetic block at the T1 to...” NCT06068166

“This study will compare the effects of remifentanil (bolus dose of 0.25 mcg/kg or 0.5 mcg/kg) to lidocaine (bolus dose of 1mg/kg) when given prior to emergence to prevent...” NCT01026129

“1 ml epinephrine (1:1000 Martindale Pharma, an Ethypharm Group Company, ampoule 1 mg added to 9 ml of normal saline, then 1 ml of that put in nebulization cup + 2 ml lidocaine...” NCT05738564

“Group I patients received cervical epidural injections with lidocaine 0.5% preservative-free, 5 mL, whereas Group II patients received 0.5% preservative-free lidocaine mixed...” PMID 24077193 Sep 2013

“heparin sulphate 40,000 IU (4 cc of 10,000 units/cc), lidocaine 2% 16 ml, Sodium bicarbonate 8.4% 4 ml and Kenalog 40 mg (1cc) to reach a total fluid volume of 25 ml will be...” NCT02870738

“This study aims to compare the effectiveness of warm 2% lignocaine (lidocaine) versus conventional room temperature 2% lignocaine for achieving successful inferior alveolar...” NCT06806202

“The active substances in Fydrane are: tropicamide 0.04 mg (anticholinergic), phenylephrine hydrochloride 0.62 mg (alpha sympathomimetic) and Lidocaine hydrochloride 2 mg (amide...” NCT04396301

“LiRIS® 400 mg is a drug-device combination product which is placed in the bladder during cystoscopy, remains in the bladder for up to 14 days gradually releasing lidocaine, and...” NCT01879683

“The EMLA group received EMLA cream which consisted of 2.5% lidocaine and 2.5 % prilocaine in 2 ml of water/oil emulsion and then they received tegaderm as the dressing for...” NCT03134391

“2 ml methylprednisolone acetate 40mg/ml (total 80mg methylprednisolone acetate) together with 1 ml lidocaine 2% (total 3 ml solution) will be directly injected under ultrasound...” NCT05339542

“An injection of 5 ml of 5% dextrose prolotherapy using 2.5 ml 10% dextrose, 1 ml 2% local anesthetic (lidocaine), 1.5 ml 0.9% saline will be administered to the active group...” NCT04941118

“EMLA®, a topical anesthetic cream containing lidocaine and prilocaine, will be applied under occlusion prior to tape application during 30 minutes with the aim of anesthetize...” NCT07034456

“liposome-encapsulated 2% ropivacaine, liposome-encapsulated 1% ropivacaine, a eutectic mixture of 2.5% lidocaine and 2.5% prilocaine (EMLA), and liposomal placebo gel,...” PMID 21106282 Nov 2010

“LiRIS® is a drug-device combination product which is placed in the bladder during cystoscopy and remains in the bladder, gradually releasing lidocaine until removed from the...” NCT02395042

“For suprascapular nerve block, a solution consisting of 5 ml 2% lidocaine, 1 ml Betamethasone dipropionate + Betamethasone sodium phosphate (6.43 mg/ml + 2.63 mg/ml), 4 ml...” NCT05260125

“Ultra sound guided injection af 1 ml og Glucocorticosteroid (methylprednisolone 40 mg) and 1 ml of lidocaine 5mg/ml from the medial side profound to the thickened part of the...” NCT01994759

“Anesthesia will be maintained with Sevoflurane, Magnesium, Lidocaine, Ketamine, Decadron, Ondansetron, and Ketorolac at a concentration range/dose(s) based on the clinical need...” NCT03367988

“On the other hand, a recent study showed the interest of administering lidocaine 2% by J-tip, a needle-free injection technique not available in France, before infiltration of...” NCT05032508

“In addition to propofol as a hypnotic and rocuronium as a muscle relaxant, patients in the opioid-sparing group will receive Ketamine, Fentanyl, Lidocaine, Magnesium,...” NCT05485480

“A pre-prepared 50 ml syringe is utilized, containing 400 mcg of dexmedetomidine (4 ml), 50 mg of S-ketamine (2 ml), 400 mg of 2% lidocaine (20 ml), and 0.9% NaCl to a total...” NCT07084753

“Antoniades et al. demonstrated that topical lidocaine through the bronchoscope significantly decreased cough frequency and the total dose of sedation required during flexible...” NCT03109392

“5 milliliters (mL) injection of corticosteroid (1cc Kenalog, 4cc Xylocaine) Kenalog - 40 (triamcinolone acetonide injectable suspension, USP) Xylocaine - MPF (lidocaine HCl...” NCT06703970

“Each actuation of the pump spray dispenses 130µl, corresponding to a dose of 7.7mg lidocaine. Three pumps will dispense 390µl of a 9.6% solution, delivering a total dose of...” NCT04247230

“a standard Tuohy block needle will be advanced through a skin wheal of lidocaine until its tip is in the hypoechoic area immediately distal saphenous nerve adjacent to the...” NCT06784882

“One ml Lidocaine (10%) will be injected at the end of therapy since irritation of nerve fibers by the electrical field (without thermolesion) has been described as occurring frequently.” NCT04737993

“After infiltration with 1 mL of 1% lidocaine, local anesthetics (20 mL of 0.5% ropivacaine) will then be injected in 5 mL aliquots to achieve circumferential spread around the nerve.” NCT02517437

“after which 1.4 mL of a mixture of 2 mg of dexamethasone sodium phosphate and 1 mL of 1% plain lidocaine will be slowly injected through the radiofrequency treatment cannula needle.” NCT03131466

“1.5 cc 30% dextrose solution and 1.5 cc 2 lidocaine mixture with a 25 gauge needle into the medial plantar region cc 2 lidocaine mixture will be made sterile with 3 cc 15% dextrose.” NCT05984121

“Participants will be given three sprays of 10% Lidocaine (Lidocaine 10% pump spray, Egis) 3 minutes before the interventionist performed the insertion of a catheter into their vein” NCT07212192

“The purpose of this study is to compare the effects of vapocoolant spray and topical lidocaine 2.5% + prilocaine 2.5% cream (EMLA) on reducing pain during needle electromyography.” NCT01606046

“20 mL of local anesthetic solution (10 mL of 0.5% bupivacaine and 10 mL of 2% lidocaine) was injected bilaterally into the erector spinae plane at the T7-T8 level before incision.” NCT07057934

“The selected patients will receive transforaminal epidural injection of premixed steroids with local anesthetic in a total volume 2 ml (7 mg Betamethasone and 20 mg Lidocaine 2%)” NCT05288920

“1 mL of triamcinolone acetonide 40 mg (KENACORT-A IM/Intra-articular Retard 40 mg ampoule) and 1 mL of 2% lidocaine (Aritmal 2% ampoule) will be injected over the plantar fascia.” NCT07120204

“Commercially available Lidoderm (lidocaine patch 5%) was provided to patients with up to four patches applied topically once daily (q24h) to the area of maximal peripheral pain.” NCT00904020

“tumescent formulation of cefazolin (1gm) and metronidazole (500mg/100ml) in a dilute solution of lidocaine (1gm), epinephrine (1mg) in 100ml and sodium bicarbonate (10mEq/10ml)” NCT03226626

“Before intubation of the trachea, a lidocaine 1 mg / kg bolus was added intravenously, with the simultaneous establishment of a continuous infusion at a dose of 1.5-2 mg/kg/h.” NCT05514652

“EMLA cream 5% 25g lidocaine, 25g prilocaine; Astra Zeneca. Topically applied followed by Tegaderm dressing to cover. Length of duration monitored and recorded as part of study” NCT06274905

“A total of 2 ml solution (1 ml betamethasone and 1 ml 2% lidocaine) is injected perineurally around the median nerve under ultrasound guidance at the scaphoid-pisiform level.” NCT07105540

Lidocaine (Xylocaine) has a better pharmacokinetic and pharmacodynamics profile than levobupivacaine and is also widely used as local anaesthetic agent in clinical practice.” NCT04397484

“Transforaminal epidural steroid injection (ESI TF) with corticosteroids like Methylprednisolone, Levobupivacaine and Lidocaine according to the protocol of the institution.” NCT06545812

“general anesthetic by midazolam 0.02 mg kg-1 , propofol 2-3 mg kg-1 and lidocaine 0.5 mg kg-1 , fentanyl 2 μg kg-1 , atracurium 0.5 mg kg-1 , isoflurane in 50% oxygen/air.” NCT03569046

“10mg of dexamethasone (1cc) mixed with 1cc of 2% preservative-free xylocaine (lidocaine) will be injected on each side of the stenotic segment under fluoroscopic guidance” NCT01995461

“will receive a total of 2 mg.kg-1 of 2% lidocaine HCl (Xylocaine, Astra-Zeneca,) in 3 mL of normal saline (1.5 ml around each tonsil), 5 minutes before surgical incision.” NCT01552096

“5 cc PRP injection (consisting of their own PRP) with 1 cc of 1% lidocaine and 1 cc of 0.5% ropivacaine into the subacromial space, administered by an orthopedic surgeon.” NCT01123889

“EMLA® Test Patch containing the active ingredients lidocaine base 25 mg/g and prilocaine base 25 mg/g in an oil-in-water emulsion saturating the absorbent cellulose disc.” NCT03313336

“All analgesic procedures such as lidocaine, paracetamol, ultracaine, and paracervical block with ultracaine can be used for reducing pain score in postoperative period.” PMID 24455735 Dec 2013

“Participants who take part in this study, may receive 6cc of 2% lidocaine gel or 6cc of a non-medicated gel in the vagina before a paracervical block for IUD placement.” NCT06974032

“Effect of Local Anesthetic EMLA (Lidocaine 2.5% and Prilocaine 2.5%) Cream and Reduction in Dose, Pain and Intravenous Analgesic During Permanent Pacemaker Implantation” NCT02016976

“receive the Twin block local anesthetic (using the standard dental anesthetic 1.8 cc 2% lidocaine with 1:100,000 epinephrine), once, on the side/s of their extraction/s” NCT04414917

“Compare the opioid based anesthesia with Fentanyl and Remifentanyl to opioid free anesthesia with dexmedetomidine and lidocaine and their effect on postoperative pain.” NCT03417193

“Participants in this arm will receive an inferior alveolar nerve block with 1 cartridge (1.8 mL) of 2% Lidocaine 1:100,000 epinephrine following endodontic treatment.” NCT05338671

“The study intervention was the administration of 10 mg of intranasal lidocaine in one nostril using 1 spray of 0.1mL of a 10% lidocaine solution 5 minutes before NPS.” NCT04901065

“Supracapsular nerve block: injection of 10 mL of 1% lidocaine (2 mL along the needle path and 8 mL around the nerve), followed by an injection of 1 mL of DIPROSTENE®.” NCT07680504

“steroid injectant consists of 1 ml of Compound Betamethasone Injection (Diprospan®, Schering-Plough Labo N.V., Belgium) and 4ml of 0.2% lidocaine will be injected.” NCT03101033

“Patients will be nebulized with mixture of 2% lidocaine 10 ml and dexmedetomidine 1 μg/kg by using wall nebulizer for 15 min before awake fiberoptic intubation.” NCT06088875

“Prior to the epidural injection a local anaesthetic solution of 1% lidocaine will be injected into the relevant subcutaneous and ligamentous interlaminar space.” NCT01934868

“a combination topical anesthetic, consisting of 20% lidocaine, 4% tetracaine and 2% phenylephrine (TAC Alternate Gel, Compounding Arts Pharmacy, Lafayette, LA).” NCT00846690

“The study drug, EVEGYN 600 mg/1000 mg/100 mg Vaginal Ovule, is a fixed-dose combination of 600 mg fenticonazole nitrate + 1000 mg tinidazole + 100 mg lidocaine.” NCT05361369

“To alleviate the discomfort on local tissues, the suspension injected into the infrapatellar fat pad will be pre-mixed with 0.5 ml saline and 0.5 ml lidocaine.” NCT05291650

“Group l include 50 patients who will be injected with one intra\_articular injection of 2 ml of methylprednisolone acetate 40 mg/ml mixed with 2ml of lidocaineNCT05742061

“EVEGYN A: Fixed-dose combination of 600 mg fenticonazole nitrate + 1000 mg tinidazole + 100 mg lidocaine vaginal ovule Single dose, single administration (1x1)” NCT06056947

“1 mL of 4 mg/mL dexamethasone with 2 mL of 1% lidocaine OR 1 mL of 4 mg/mL dexamethasone, 1 mL of 2% lidocaine and 1 mL saline injected into the plantar fascia” NCT05367271

“Infiltration of 40 to 80 ml of a non-adrenalized 0.5% lidocaine solution into the vaginal wall at the level of the vaginal pouches, under ultrasound guidance.” NCT05567315

“The administered dose will include 0.2% lidocaine combined with 0.2% ropivacaine, at a dose of 0.4 ml/kg per side, without exceeding toxic dose limits per kg.” NCT07139691

“The ultrasound will be placed in the supraclavicular fossa, and the skin and subcutaneous tissues will be infiltrated lateral to the probe with 2% lidocaine.” NCT03138577

“Solutions contain either 0.3% Ropivacaine, 1% Procaine, 0.5% Lidocaine, 0.25% Bupivacaine, or a mixture of 0.25% Bupivacaine and 2% Lidocaine in a 9:1 ratio.” NCT06617065

“The del Nido components are: Plasma-Lyte A (1000ml), Mannitol 20% (16.3ml), MgSO4 50% (4ml) , NaHCO3 8.4% (13ml) , KCl 2mEq/mL (13ml), Lidocaine 1% (13ml).” NCT03818126

“PSD502 is a topical (applied to skin) anesthetic spray containing a mixture of two drugs called lidocaine and prilocaine that will be applied to the penis.” NCT03578783

“Intravenous lidocaine (IVL), an alternative to epidural analgesia (EA) for laparotomies, has demonstrated anti-inflammatory and anti-hyperalgesic effects.” PMID 41790838 Mar 2026

“For the local anesthesic, the doctor uses in both arms of the study a 20 ml vial of lidocaine hydrochloride without adrenaline for injection dosed at 2%.” NCT05178849

“will receive ultrasound-guided intra-articular SIJ injection with 40 mg of methylprednisolone with a uniform dose of 2 mL of 2% lidocaine hydrochloride.” NCT05134181

“Patients will receive injection of 1 microgram/kg dexmedetomidine average (70-100-microgram) (0.7-1ml) plus 4ml lidocaine injection nearby median nerve.” NCT06133712

“The 5 cc BMAC dose or 1 cc triamcinolone of 40 mg with 4 cc of lidocaine 1% will be injected into a single affected hip joint under ultrasound guidance.” NCT04990128

“Combination steroid (Celestone) and anesthetic drug (Lidocaine) will be injected into the patient's subacromial bursa via needle guidance of ultrasound” NCT02246530

“A lidocaine bolus of 1.5 mg/kg will be given with induction of anesthesia followed by an infusion of lidocaine at 2 mg/kg/hr until the end of surgery.” NCT03908944

“a total of 4 mL of local anesthetic solution consisting of 2 mL of 0.5% bupivacaine and 2 mL of 2% lidocaine (Aritmal) will be injected on each side.” NCT07608861

“Induction with 1% propofol (2-3 mg/kg), fentanyl (1-3 mg/kg), and Rocuronium 1-1.5 mg/kg. Before the injection of propofol, 5 mL 1% lidocaine (50 mg)” NCT04281017

“Local anesthesia (e.g., 2% Lidocaine) and conscious sedation (e.g., Fentanyl and Midazolam) will be administered to the patient during the procedure” NCT06426992

“The diagnostic injectate will be a local anesthetic without corticosteroid (1% lidocaine) with low volumes of 0.5 ml per branch to limit diffusion.” NCT07273006

“mLDG (lidocaine 0.16mg/mL, dexamethasone 0.02mg/mL, and gentamycin 0.16mg/mL) dissolved in 0.9% saline solution was administered three times a day.” NCT02577393

“This research study uses Eutectic Mixture of Local Anesthetics (EMLA) Cream (lidocaine 2.5% and prilocaine 2.5%) as the topical anaesthetic agent.” NCT05078463

“Following nasopharyngeal anesthesia (topical lidocaine), the fiberoptic bronchoscope will then be passed into a pulmonary segment or subsegment.” NCT02401074

Lidocaine patch 5% (Lidoderm®, Endo Pharmaceuticals Inc.), 2 patches applied once daily (q24h) directly to the most painful area of the low back” NCT00904397

Lidocaine 5% patch (Lidoderm®,Endo Pharmaceuticals Inc.), 2 patches applied directly to the most painful area of the low back once daily (q24h)” NCT00904111

“Single intra-articular injection of dexamethasone 4 mg (0.5 mL) combined with lidocaine 2% (0.5 mL), total 1 mL, into the superior joint space.” NCT07691684

“The VASAUC was significantly smaller after oral rinse with 0.05 mol/L GABA, 0.5 mol/L GABA, and 1% lidocaine than after oral rinse with water.” PMID 29024230 Oct 2017

“1 mL of 2% lidocaine with epinephrine was delivered via buccal infiltration using a conventional aspirating syringe and 27-gauge short needle.” NCT06992193

“one press of the spray pump release 0.20 mL of the solution containing 4 mg lysozyme, 0.3 mg cetylpyridine and 0.1 mg lidocaine hydrochloride.” NCT03282045

“Comparing the two versions (the room temperature and + 4°C) of the gold standard of local anesthetics, the solution, which contains lidocaine.” NCT07198022

“hydrogels containing LAs - lidocaine and prilocaine (both at 2.5%) encapsulated in CLN (XAN-CLN) or not (XAN-CLN ), EMLA and placebo hydrogel” NCT05912335

“Products containing lidocaine are used in everyday practice, sometimes combined with vasoconstrictors such as oxymetazoline or phenylephrine.” NCT04583137

“Multiprofen-CC™ is a multimodal topical cream including ingredients ketoprofen (10%), baclofen (5%), amitriptyline (2%), and lidocaine (5%).” NCT06202989

“Lumbar Transforaminal Epidural Steroid Injections was administered, consisting of 4 mg dexamethasone and 0.33% lidocaine in a 3 ml solution” NCT06656429

“Will be carried out topical anesthesia of the pharynx with lidocaine spray (10%) 6 puffs and instillation of nasal vasoconstrictor 4 drops.” NCT03288259

“Local anesthetic infiltration of 2% lidocaine (3ml) along with injection anaesthetic agent consisting of isobaric bupivacaine 0.25% (20 ml)” NCT06301503

“with 2ml of lidocaine hydrochloride 2% (Hameln Pharmaceuticals Ltd, Gloucester, UK) into the subacromial space of their affected shoulder.” NCT02669303

“intracarpal injection of methylprednisolone acetate 40mg, and 40 mg lidocaine (20 ml, volume) will be performed under sonographic guidance” NCT03742466

“Priformis intramuscular injection will be administered with 5 cc 2% lidocaine, accompanied by a nerve stimulator under ultrasound guidance” NCT05450913

“This cream consists of lidocaine (5% w/w), hydrocortisone acetate (7.5% w/w), aluminium sub-acetate (3.5% w/w), and zinc oxide (18% w/w).” NCT02301052

“Intervention group will receive 30 ml of a 50/50 mixture of isobaric bupivacaine 0.5% and lidocaine 1%, containing 8 mg of dexamethasone.” NCT07313553

“combination of medications may be used such as a local anesthesia, ibuprofen, acetaminophen, gabapentin, ketamine, lidocaine, and opioids” NCT04010266

“LMX4 is a topical anesthetic consisting of 4% lidocaine which is Food and Drug Administration (FDA) approved for topical use in children.” NCT05461053

“The dental local anesthetic (2% lidocaine with 1:100,000 epinephrine) will be delivered as the Temporo-masseteric Nerve Block injection.” NCT07094542

“single injection 1.5 ml of methylprednisolone (40mg/ml) and 1.5 ml of 2% lidocaine (20mg/ml) with 0.5 ml of saline (total volume 3.5 ml)” NCT02334475

“20cc of 2% lidocaine with 1:200,000 epinephrine + 20 cc of 0.5% bupivacaine with 1:300,000 epinephrine will be injected around the nerve” NCT02280291

“Treatment Period 1: continuous release of lidocaine inserted into the bladder by cystoscopy on Day 0 and removed on Day 14 of Period 1.” NCT02411110

“10 mg lidocaine/spray. The patient will be sprayed three times and get a maximal dose of 30 mg lidocaine just before the examination.” NCT01832675

“As a topical pre caudal epidural block anesthesia, spinal needle insertion site was injected subcutaneously using 3ml of 2% lidocaineNCT03175913

“This arm will receive a Triple Mixture oral rinse (combination of 0.19% w/w Lidocaine, 0.29% w/w Nystatin, and 5.50% w/v Hydroxides).” NCT06875791

Lidocaine (Xylocaine), also called lignocaine, is a potent local anesthetic agent, widely used both topical and injection anesthesia.” NCT03265197

“Patients will receive mixture of bupivacaine 0.5% (4.5 ml) + lidocaine 2% (4.5 ml) + dexmedetomidine 50 μg (1 ml) in peribulbar block” NCT05692167

“These subjects will first receive a topical anesthesia to the skin and underlying tissue in a maximum amount of 5 ml of 1% LidocaineNCT03543033

“Peroperative opioid free anesthesia will be obtained via a combination of dexmedetomidine, ketamine, lidocaine and magnesium sulfate” NCT03124680

“The injections will consist of a solution containing 1 ml of 40 mg/ml triamcinolone acetonide and 1 ml of 1% lidocaine in each site.” NCT05980572

Lidocaine patch 5% (Lidoderm®, Endo Pharmaceuticals Inc.), 1⅓ patches applied topically to each affected knee every 24 hours (q24h)” NCT00904605

“Intra-articular injection consisting of 80 mg of methylprednisolone acetate, 2 mL of lidocaine (1%), and 4 mL of ropivacaine (0.5%)” NCT07497737

“administration of 20 ml volume of local anesthetics (Lidocaine 2% +Bupivicaine 0.5% 1:1 mixture + 8mg dexamethasone) on each side” NCT06155097

“LiRIS contains Lidocaine, a marketed drug (approved by Health Canada) which is commonly used for local (skin or oral)anaesthesia.” NCT01150565

“3mL lidocaine (without epinephrine) 1% solution combined with 1mL triamcinolone acetonide injectable solution, USP (40mg per mL)” NCT07544576

“Dex group: Dexmedetomidine 2mcg/ml-containing 1% lidocaine scalp injection by neurosurgeon(dosage: according to incision length)” NCT01606969

“For local anesthesia, 1 mL of 1% lidocaine will be injected with a 25 gauge 2-inch needle into the skin and subcutaneous tissues” NCT07278323

“Trigger point injection with 25G needle on the shoulder before surgery(0.5% procaine, 0.25\~0.5% lidocaine, 0.125% bupivacaine)” NCT01845532

“This is 40mg of a non-fluorinated injectable glucocorticoid, methylprednisolone acetate (1cc) combined with 1cc of 1% LidocaineNCT02044991

“A thick layer of cream (lidocaine and propiocaine 2.5%/2.5%) will be applied on a 1x1 cm2 area of skin on the cannulation site.” NCT04275336

“Intravesical Alkalized Lidocaine for the Treatment of Overactive Bladder (OAB), a Randomized, Double-blinded Controlled Trial” NCT00427648

“Experimental - A multimodal topical cream treatment with Ketoprofen, Baclofen, Amitryptiline, and lidocaine in a carrier gel.” NCT03199417

“Lidoderm (lidocaine patch 5%), up to four patches applied topically once daily (q24h) to the area of maximal peripheral pain” NCT00904202

“Standard care includes intravesical instilled 1-2% lidocaine with a dwell time of at least 15 minutes before the procedure.” NCT07387315

“EMLA anesthetic ointment (AO-Astra Zeneca) is an emulsion of lidocaine 2.5% and prilocaine 2.5% in a ratio of 1:1 by weight” NCT03501212

“Eutectic mixture of lidocaine 25 mg/g and prilocaine 25 mg/g cream (EMLA cream) will be applied at this test region at t1.” NCT02246179

“These studies have shown fentanyl and lidocaine to be effective in reducing the incidence of pain on rocuronium injection.” PMID 18008122 Nov 2007

“The participants will receive oral triazolam with topical proparacaine and sub-tenon's mixture of lidocaine and marcaine.” NCT04346095

“The project manager will give the participants one injection with cortisone and lidocaine in the lateral hip at baseline.” NCT05086926

“The low pH causes burning pain when applied, that is why it is coadministered with lidocaine to reduce pain of injection.” NCT01651988

“50 g of a local anesthetic agent containing 2.5% Lidocaine and 2.5% Prilocaine (EMLA®, AstraZeneca - Södertälje, Sweden)” NCT00959595

“30ml total volume of 0.25 plain bupivacaine 1.5mg/kg with lidocaine 1% 3mg/kg with 8mg dexamethasone in group A patients” NCT06131593

“Marcaine® (bupivacaine HCl) 0,5% and Xylocaine® (Lidocaine HCL) 2% = 2:1 Given in Femoropopliteal block group (Group F)” NCT06702202

“The lidocaine-based solution used for local anesthesia of the TM is Tymbion (2% lidocaine HCl/ 1:100,000 epinephrine).” NCT03197558

“Postoperative topical lidocaine and PCA (piritramide 0.5 mg/ml; infusion 0.5 mg/h, bolus 1.5 mg, lock out 20 minutes)” NCT05831761

“injections of 3.6 mL of 2% lidocaine with 1:100,000 epinephrine Intervention: inferior alveolar nerve block injection” NCT02054767

“Subcutaneous local anesthesia with 1% lidocaine without epinephrine is administered to the skin overlying the joint.” NCT05747469

“The investigator will add Sodium bicarbonate in lidocaine with adrenaline (1:80,000 ) for Buffered Local anesthesia.” NCT07592143

“Ultrasound-guided injection of 1 ml lidocaine combined with 1 ml betamethasone administered at the A1 pulley level” NCT07681804

“The study group (OFA group) will receive a combination of clonidine, magnesium sulfate, ketamine, and lidocaine.” PMID 34838109 Nov 2021

“preemptive epidural analgesia with 3 ml lidocaine 20 mg/ml, 3 ml, 10 ml morphine 0.4 mg/ml plus 5 ml bupivacaine” NCT01513564

“1% TXA mixed with standard local consisting 1/4% lidocaine with 1:100,000 epinephrine with saline as the control” NCT06345833

“with 4.5 ml ethanol 96% + 1.5 ml of lidocaine 10 mg/ml + 2 μg/kg dexmedetomidine diluted in 0.9% sterile saline” NCT05291364

“Topical 5% lidocaine medicated plaster treatment was administered by patients to the area of most painful skin.” PMID 19301937 2009

“Then one area will be pre-treated with cutaneous 2.5% lidocaine/2.5% prilocaine cream (EMLA cream) for 1 hour.” NCT04858360

Lidocaine spray as a local anaesthetic agent was applied to the cervix before intrauterine device application.” NCT07155785

“A single injection of triamcinolone acetonide 40mg mixed with an equal volume of 1% lidocaine is administered.” NCT07043179

“A single injection of triamcinolone acetonide 40mg mixed with an equal volume of 1% lidocaine is administered.” NCT07042282

“Ultrasound guided ESP block will perform with 15 ml bupivacaine+ 5 ml lidocaine at the T10 level bilaterally.” NCT04148729

“Viscous Lidocaine, Diphenhydramine, and Aluminum-magnesium Hydroxide/Simethicone Antacid Suspension Mouthwash” NCT03490396

lidocaine (1mg/kg), esketamine (0.5mg/kg), propofol (1-2mg/kg) and rocuronium (0.6mg/kg) were infused slowly” NCT05577962

“Targeted topical analgesics such as 5% lidocaine patches have been known to improve acute and chronic pain.” PMID 36089597 Sep 2022

“An injection of Lidocaine into the tendon sheath to break up adhesions that could be causing the condition.” NCT03363789

“After pretreatment lidocaine 70 mg/g + tetracaine 70 mg/g cream (LTC) will be applied at this test region.” NCT03279757

“Epidural injectate will be 2cc of .25-1% lidocaine followed by 1-3cc of 1% lidocaine in an opaque syringe.” NCT01238536

“The standard protocol used a pre-procedure instillation of 50 ml of 1% lidocaine and 50 ml of 0.9% saline.” PMID 40025238 Mar 2025

“In addition, 40 mg of Lidocaine were added, this aimed to reduce the pain on injection caused by Propofol.” NCT04285528

“Effect of Intravenous Infusion of Lidocaine on Patients Undergoing Radical Resection of Colorectal Tumors” NCT05484687

“An opioid-free general anesthetic technique utilizing dexmedetomidine, ketamine, and lidocaine infusions” NCT02752477

“The intraperitoneal administration of lidocaine solution (total dose, 3.5 mg/kg) will be done as follows” NCT03693820

“The study will compare corticosteroid injections with lidocaine to lidocaine only in a crossover design.” NCT05035810

“Synera Patch (lidocaine 70 mg/ tetracaine 70 mg) will be applied for 30 minutes to the venipuncture site” NCT01115062

“rescue infiltration analgesia using 1 % lidocaine administered by the operator into the operation field.” NCT04500249

“A pack of lidocaine gel will be applied in the external canal for 10 minutes in EAC to induce anesthesia” NCT05112354

“peribulber injection of lidocaine 2٪ (4 ml) + Cisatracurium (0.5 mg in 0.5 ml) + Normal Saline (0.5 ml).” NCT07519694

“an injection of 1ml of 1% lidocaine per rib and ultrasound guided cryoablation of the intercostal nerves” NCT06347874

“2 puffs of lidocaine-prilocaine spray into the cervix and cervical canal 5 minutes before the procedure” NCT06769204

“10% Lidocaine was applied to the laryngoscope blade and 0.9% normal saline was applied to the trachea.” NCT01737437

“solution containing sterile, cooled 0.9% sodium chloride and 1% lidocaine with epinephrine (1:100,000)” NCT06820164

“will be anesthetized with 1 ml of 1% lidocaine and a 22 Gauge, 10 cm-5 mm RF cannula will be inserted.” NCT06683924

Lidocaine (LID) loading dose (1 mg/kg) followed by a continuous infusion till 24 h PO as 1.5 mg/kg/h.” NCT06907277

“General anesthesia with Lidocaine 1.5mg/kg, Fentanyl 2 mcg/kg, propofol 2 mg/kg, Rocuronium 0.6 mg/kg” NCT06892600

“Steroid injection , Triamcinolone acetonide(40mg/ml) 1 ml + 1%Lidocaine without adrenaline 3 ml = 4ml” NCT06453603

“The study drug contains either 30 ml of 2% lidocaine or 0.9% saline, depending on group allocation.” NCT06490718

“The content of the steroid solution will be 1 ml of 1% Lidocaine + 1 ml (40 mg) methylprednisolone.” NCT04709484

“local anesthesia cream (lidocaine cream) will be applied in external auditory canal for 15 minutes” NCT05786378

“one cream will be an anesthetic (lidocaine and prilocaine) and the other will be a placebo lotion.” NCT01324843

“A skin wheal will be made by 1 ml of lidocaine HCl 2% at L3-4 interspace using a 25-gauge needle.” NCT07564180

“2% lidocaine with 1:100,000 epinephrine is the standard dental local anesthetic in universal use.” NCT04880707

“It is composed by Dexmedetomidine (Dexdor), Lidocaine, Magnesium Sulfate and ketamine (Ketolar).” NCT05887258

“For solution, 1 cc 2% lidocaine, 5 cc 30% hypertonic dextrose and 4 cc 0.9 % isotonic were used.” NCT04395417

“A placebo patch and a lidocaine patch will then be applied to the volar aspect of each forearm.” NCT00373893

“OFA (n=159) consisting of intravenous ketamine, dexamethasone, lidocaine, and magnesium sulfate” PMID 42190101 May 2026

lidocaine 1.5 mg/kg and Fentanyl 1 to 2 mcg/kg followed by IV lidocaine infusion at 1.5 mg/kg/h” NCT07116564

“The Effectiveness of Mesotherapy (Lidocaine and Proxicam) in the Treatment of Chronic Migraine” NCT06118190

“after a test does of 1% lidocaine, 1% mepivacaine will be injected near the stellate ganglion.” NCT05445921

Lidocaine 2mg Kg-1 in normal saline (total volume 25mL) was infused after tracheal intubation” NCT02224170

“For Lido-IV group, patients received a loading dose of Lidocaine than a continuous infusion.” NCT06383845

“The standard mouth rinse contains 40% Benadryl, 40% Maalox, and 20% of 1% Viscous Lidocaine.” NCT02300727

“Ropivacaine .5% and lidocaine 1% to the area behind the muscle Quadratus Lumborum location 1” NCT04588389

Lidocaine spray 10 % (Xylocaine 10% pump spray; AstraZeneca BV, Zoetermeer, The Netherlands)” NCT06354816

“after skin infiltration with 3 ml of 2% lidocaine, a 22G, 50-mm, insulated facet type needle” NCT03746418

“10 mL of 1% lidocaine with epinephrine combined with 10 mL of 0.5% bupivacaine hydrochloride” PMID 42100467 Apr 2026

“using 1.5ml of 2% Lidocaine hydrochloride (1ml: 0.5mg) and 500ug of Vitamin B12 (1ml: 0.5g)” NCT06176404

“Ultrasound-guided Popliteal Plexus Block using 10 ml of of Lidocaine Hydrochloride 10 mg/ml” NCT05464862

“under US guidance, 2ml triamcinolone (1ml/10mg), 0.5ml distilled water and 1ml 1% lidocaineNCT02702206

“Group LWI+IPLA will given 30 ml %0,5 bupivacaine+%2 lidocaine infiltration and instillation” NCT05405049

“Topical anaesthesia with lidocaine will be provided through nebulisation and instillation.” NCT03546088

“Group L received TPI with a 3.2 ml of a 1:1 mixture of 1% lidocaine and 0.9% normal saline” NCT02293083

“LiRIS 400 mg contains lidocaine which is gradually released into the bladder over 14 days.” NCT01824303

“The -Mulimix regimen consists of 50mcg dexmedetomidine, 500 mg lidocaine and 50mg ketamine” NCT07568938

lidocaine local anaesthetic lidocaine 20 mg/ml, adrenalin 12,5 µg/ml maximum dosage 10 ml.” NCT00805298

“The Multimix regimen consists of 50mcg dexmedetomidine, 500 mg lidocaine and 50mg ketamine” NCT05752799

Lidocaine HCI (1.7mL) 2% concentration with epinephrine (1:100,000) is the control agent.” NCT04787731

“Intravenous injection of 10 ml of Lidocaine 1% solution administered over 2 to 4 minutes.” NCT05653401

“using the standard dental local anesthetic, i.e,. 2% lidocaine with 1:100,000 epinephrine” NCT05335070

“Dexmedetomidine and lidocaine are administered during anesthesia, and opioid is not used.” NCT05076903

“The mixture will contain: 3 ml lidocaine 2%, 3 ml lidocaine 2% with epinephrine 1/200 000” NCT02355678

“In addition, Lidocaine will be added to reduce the pain on injection caused by Propofol.” NCT04473846

Lidocaine hydrochloride 20 mg/mL, solution, 20 mL ampoule for intravenous administration” NCT07274254

“lubricant gel with lidocaine will be administered to all patients just before cystoscopy” NCT03831321

“Injection of methyl prednisone and lidocaine in the tendon sheet volar to the MCP-joint” NCT04568993

“Each ZTLIDO contains 36 mg of lidocaine (18 mg per gram adhesive) in a non-aqueous base” NCT06030297

“Group I received 10 mL caudal epidural injections of local anesthetic, lidocaine 0.5%;” PMID 22828681 Jul 2012

“Triamcinolone Acetonide 40mg/ml, 1ml, and Lidocaine 2ml as the active comparator group” NCT04916353

“topical anaesthetic gel (containing lidocaine active ingredient) administered rectally” NCT04031131

“Chemoembolization: Lipiodol emulsion (lipiodol 10ml+ Oxaliplatin 85mg +Lidocaine 1ml)” NCT05340231

“Single dose of Rocephine® (= ceftriaxone 1g + lidocaine 35mg) intramuscular injection” NCT05027516

“Subsequently, 1 mL of 5% injectable lidocaine is administered into each nasal cavity.” NCT07354464

“2% lidocaine with 1:100,000 epinephrine as the local anesthetic for Group 2 - Control” NCT03243032

“Patients will receive 2 ml of 2% lidocaine using a nasal applicator in each nostril.” NCT06974617

“a eutectic mixture containing 25 mg/g of lidocaine and 25 mg/g of prilocaine (EMLA®)” NCT01860235

“Afterwards a continuous intravenous infusion of lidocaine and ketamine was started:” NCT04355468

“Propofol 2mg/kg plus lidocaine 1mg/kg over 10 min and 10 min before end of surgery.” NCT07601698

Lidocaine was injected on 16 patients' three trigger point in the masseter muscle.” NCT05228327

“Octocaine® (1.8mL/cartridge contains 20mg/mL Lidocaine + 1:100,000 epinephrine)” NCT05804630

“A compound containing viscous lidocaine and magnesium aluminum oxide (Maalox®);” NCT01262560

“Instead of a regional block, an intravenous infusion of lidocaine will be used.” NCT06793527

Lidocaine 2% will be mixed with bupivacaine to expedite the onset of analgesia.” NCT03730714

“1% lidocaine with 1:100,000 epinephrine injected directly into operative site.” NCT03135340

“40 mg Triamcinolone with one mL 1% lidocaine injected once into Carpal Tunnel” NCT00701233

“An inferior alveolar nerve block was given with 2% lidocaine with epinephrine” NCT05239078

“Single therapy cream containing Lidocaine. Lidocaine is a topical anesthetic.” NCT05348200

“Commercially available Lidoderm (lidocaine patch 5%) was provided to patients” NCT00904540

“Patients in both study groups will receive 1 mg/kg of lidocaine intravenously” NCT05509192

“All patients received 8 mg dexamethasone and lidocaine at a dose of 1 mg/kg.” NCT06958913

“Bupivacaine 0.25% + Lidocaine 1% + dexamethasone 4 mg + epinephrine 5 mcg/ml” NCT05834023

“then mixed with 1 mL Lidocaine 2% for a total of 3mL volume in one syringe.” NCT05589285

“EMLA cream (lidocaine 2.5% and prilocaine 2.5% in a ratio of 1:1 by weight)” NCT03072394

“intravenous lidocaine for systemic analgesic and anti-inflammatory effects” NCT07310524

“20% benzocaine gel, 2% lidocaine, 1:100k epinephrine nerve block injection” NCT02379221

“Eutectic Mixture of Local Anesthetics (Lidocaine 2.5% and Prilocaine 2.5%)” NCT05970354

“70 mg lidocaine/ 70 mg tetracaine topical patch applied once for 12 hours” NCT01654302

“Intradermal lidocaine will be used at the site of the needle insertion.” NCT02462681

“2% lidocaine injection treatment will be applied to the control group.” NCT05239091

“The new formulation ST-01 is a sustained release lidocaine formulation” NCT05193227

“Single injection of 1ml of triamcinolone (40mg/1ml) + 1ml 1% LidocaineNCT04253457

“Infiltration of lidocaine 1% with 1:100,000 epinephrine (maximum 10cc)” NCT05300685

“Maxillary anesthesia obtained by 2% lidocaine + clonidine (15 mcg/ml)” NCT02371759

“Both groups will receive lidocaine as the anesthesia for bronchoscopy” NCT02372760

“Local skin infiltration with 1-2 mL of 1% lidocaine at puncture site.” NCT07512219

“Pertubation solution of lidocaine 0.5 mg ml in Ringer-Acetate buffer” NCT03386552

“the drug mix included lidocaine, bupivacaine and water for injection” NCT02245126

“40mg of Triamcinolonacetonid is mixed with 2ml of Lidocaine 10mg/ml.” NCT01109446

“Patients will receive lidocaine infusion in the dose of 2 mg /kg/hr.” NCT05937282

“Epidural analgesia with lidocaine 2%, 1.5 ml, and Dexamethasone 8 mg” NCT04108546

“regional nerve block with a local anesthetic (Lidocaine/Bupivacaine)” NCT03453151

“Mepivacaine/Lidocaine 1.5% 10/15 ml (max dose 7 mg/kg) will be used” NCT06092541

“standard a standard combination of methylprednisolone and lidocaineNCT07217405

“using 3ml of 1.5% lidocaine and 1:200,000 epinephrine test solution” NCT04888858

“Intravesical lidocaine, heparin, sodium bicarb, Kenalog, gentamicin” NCT05658874

“5ml lidocaine will be injected 10 minutes before RZL-012 treatment” NCT05476679

“Injection of 15% dextrose with lidocaine at the lateral epicondyle” NCT00674622

lidocaine nebulizer (5 ml of lidocaine 2% with oxygen flow 8 l/m)” NCT06395727

“1 ml 40 mg Methylprednisolone + 1 ml 10mg Lidocaine + 1 ml saline” NCT00806871

“A 2% lidocaine without vasoconstrictor injection into the cervix” NCT03111342

“All patients received local anesthesia (3-5 ml of 2% Lidocaine).” NCT04985695

“patients will receive only topical anesthesia with 1% lidocaineNCT01444976

“Before induction, a lidocaine bolus of 1.5 mg/kg will be given” NCT07213687

“The bladder was instilled with 40 ml of 1% lidocaine solution” NCT06250543

“antiarrythmic drugs Lidocaine (1.5 mg / kg EV in 30 minutes).” NCT03299517

“6.5 ml of 2% lidocaine (Lidocaine HCL -Sunny Pharmaceutical)” NCT07205757

“Patients will receive Lidoderm topical 5% lidocaine patches.” NCT03120351

“application of 5% Lidocaine gel (APL, Sweden) on the gingiva” NCT02644811

“2 mL of a 50:50 mixture of 2% lidocaine and 0.5% bupivacaine” NCT01670825

“Topical gel containing lidocaine (2%) plus diclofenac (0.5%)” NCT02961855

“Dose of 3+2 ml of 1.5% lidocaine with 1:200,000 epinephrine” NCT03087604

Lidocaine mixed with diprospan injected into tender points.” NCT06344403

“epidural injection of 2% lidocaine 17 ml + 2 ml alfentanil” NCT02838056

“The patient's skin will be anesthetized with 2% lidocaine.” NCT03413163

“0.3 mL 2% lidocaine is infiltrated at the injection sites.” NCT02534012

“1 cc of 2% lidocaine into the origin of the plantar fascia” NCT01127672

lidocaine patch 5% (Lidoderm®, Endo Pharmaceuticals Inc.)” NCT00686127

Lidocaine 5% patch (Lidoderm®, Endo Pharmaceuticals Inc.)” NCT00904462

Lidocaine 1.5mg/kg IV bolus using IBW (Ideal body weight)” NCT04081545

Lidocaine loading dose of 1.5 mg/kg i.v. over 10 minutes” NCT04648540

“non-buffered LA, 2% lidocaine with epinephrine 1:100,000” NCT05757648

“They will also recieve anesthetic of 1 ml 1% lidocaine.” NCT01897259

Lidocaine is a drug commonly used for local anesthesia.” NCT04519463

Lidocaine 2% 2ml was injected into each genicular nerve” NCT05219084

“skin infiltration with 2 mL of 1% lidocaine will be done” NCT04425447

“Skin infiltration will be done using 3 ml lidocaine 2%” NCT06011746

“Multimodal IV analgesia of lidocaine, ketamine and MS” NCT06661746

“Patients using cervical lidocaine spray for analgesia” NCT06540599

“procaine 25 mg/g + lidocaine 25 mg/g (Emla 5% cream)” NCT06425978

“40 mg triamcinolone with 1% lidocaine, total of 2 ml” NCT05234840

“5mls 1% lidocaine will be used for skin infiltration” NCT03737604

“mixed with 5cc's of 1% lidocaine without epinephrine” NCT01132677

Lidocaine 0.33% and Cetylpyridinium Chloride 0.10%” NCT02931357

Lidocaine 0.5-1mg/kg/h, Ketamine 0.3-0.5mg/kg prn” NCT04894864

“4. Lidocaine 1% with Epinephrine 1:100,000 - 20ml” NCT03105674

“combination of ropivacaine 0.5% and lidocaine 2%” NCT04180943

“500 mg Lidocaine (25 ml of standard 2% solution)” NCT06343753

Lidocaine loading dose 1.5 mg/kg i.v. infusion.” NCT04941040

“after local analgesia with 3 mL of 1% lidocaineNCT05775861

“2% lidocaine with epinephrine 1: 100000 1.8 mL” NCT03176446

“including daily topical lidocaine 5% ointment.” NCT03640624

“Xylocaine - MPF (lidocaine HCl Injection, USP)” NCT06793982

Lidocaine (Rapidocain(R)): 4ml of 1% Lidocaine” NCT01807962

“Dexmedetomidine, Lidocaine, Propofol, Ketamine” NCT05172739

lidocaine 1% and bupivacaine 0,5% 1:1 mixture” NCT03454789

“with 10 ml of local anaesthetic lidocaine 1%” NCT03781908

“two puff lidocaine sprays on cervical mucosa” PMID 26609031 Oct 2015

lidocaine 25 mg/g + prilocaine 25 mg/g cream” NCT02548533

“2 mL lidocaine (10 mg/mL), total volume 5 mL” NCT07183436

lidocaine 1.5-2mg/kg (intravenous bolus)” NCT04507165

“placebo injection (Lidocaine) in capsule” NCT00840229

“0.5 ml of 1% preservative-free lidocaineNCT04544683

Lidocaine 1% with 1:100,000 epinephrine” NCT00578214

“a 1% lidocaine paracervical nerve block” PMID 28885425 Oct 2017

“2% lidocaine with epinephrine (2.25 mL)” NCT04951128

“40 mL of bupivacaine/lidocaine mixture” NCT04336917

“Local anesthesia: 2 cc of 1% LidocaineNCT00583011

“3mL of Linisol 2% (60mg of lidocaine)” NCT05930236

lidocaine / tetracaine 70/70 mg patch” NCT00765934

“A lidocaine topical anesthetic cream” NCT01708447

“2.5% prilocaine-2.5% lidocaine cream” NCT06891794

“Clonidine 1 µg/kg plus 2% lidocaineNCT02733757

“1% lidocaine paracervical injection” NCT02447029

“2.5% Lidocaine and 2.5% Prilocaine” NCT05060913

“tioconazole, tinidazole, lidocaineNCT03839875

Lidocaine iv bolus dose of 1mg/kg” NCT06736496

“adjuvant lidocaine and fentanyl” NCT03263117

“Injection of 12 mL of lidocaineNCT03356145

Lidocaine: 1.1.5mg/Kg iv bolus” NCT07558226

“Experimental: Lidocaine group” NCT04922359

“Group T (Inhaled Lidocaine)” NCT06705595

“IV-lidocaine (60 - 100 mg)” NCT07211399

Lidocaine with epinephrine” NCT05267938

Lidocaine patch q 12 hours” NCT04129086

“1% lignocaine (lidocaine)” NCT07675304

“2% Lignocaine (lidocaine)” NCT02807298

“Dexmedetomidine+LidocaineNCT05439005

“Omeza® Lidocaine Lavage” NCT05921292

lidocaine hydrochloride” NCT04880928

“0.5 mL of 1% lidocaineNCT04515966

“Xylocaine (lidocaine)” NCT01298310

“2 mL of 2% lidocaineNCT07355712

“LMX4 (Lidocaine 4%)” NCT01842373

Lidocaine 5 mg/Kg.” NCT03319563

“Drug: LidocaineNCT04634656

“Drug: LidocaineNCT03914235

Lidocaine HCl” NCT03885596

“2% lidocaineNCT06186921

LidocaineNCT07624890

NCT06767085

NCT03725228

NCT02696369

NCT04344483

NCT07347977

NCT01304082

NCT04182828

NCT03086213

NCT06653400

NCT01494636

NCT01751347

NCT02839668

NCT02696720

NCT06695585

NCT07255248

NCT00609323

NCT04817982

NCT01112748

NCT02747186

NCT04515901

NCT02696733

NCT06983886

NCT01606150

NCT07169032

NCT01111773

NCT02164929

NCT06433713

NCT03140787

NCT02420041

NCT05717361

NCT01752322

NCT00932542

NCT04773405

NCT01836614

NCT03802032

NCT00651313

NCT02748395

NCT03117166

NCT04185194

NCT03479320

NCT02616523

NCT07076641

NCT02293447

NCT01673061

NCT03382925

NCT07285980

NCT00907829

NCT02616419

NCT00591487

NCT01955967

NCT03382821

NCT02613455

NCT02162680

NCT02749123

NCT02973581

NCT02749162

NCT07169227

NCT03382743

NCT05046639

NCT06024733

NCT06381622

NCT07073846

NCT03386565

NCT07207304

NCT02920905

NCT06843343

NCT06109389

NCT01837446

NCT01515540

NCT01303614

NCT02085239

NCT03206320

NCT05125796

NCT01837628

NCT02838758

NCT05920980

NCT01494311

NCT01833819

NCT04732507

NCT02483611

NCT03801031

NCT03805282

NCT01207401

NCT07640256

NCT02751619

NCT04061057

NCT05253508

NCT02743104

NCT04940689

NCT01265446

NCT02517996

NCT02918812

NCT03799484

NCT01475253

NCT04061265

NCT01833221

NCT07644923

NCT01243112

NCT05044468

NCT02455232

NCT05044429

NCT03540030

NCT01387568

NCT04992572

NCT04650282

NCT03630198

NCT04650074

NCT04176705

NCT03806374

NCT01838993

NCT07256834

NCT03953001

NCT02033356

NCT06380764

NCT06837519

NCT06979141

NCT06266481

NCT03806595

NCT05573191

NCT04570293

NCT00372658

NCT04355598

NCT02084706

NCT02332057

NCT04176419

NCT00925353

NCT06795100

NCT04703127

NCT07031206

NCT05749614

NCT06362915

NCT00528502

NCT07480135

NCT03537534

NCT07546370

NCT02454894

NCT03797703

NCT04648891

NCT02741232

NCT04703803

NCT04356352

NCT06491485

NCT03390790

NCT05329116

NCT07638254

NCT02930551

NCT05250791

NCT06848764

NCT03391427

NCT01841294

NCT04339361

NCT04571879

NCT05885230

NCT04192773

NCT03634605

NCT01830881

NCT01302483

NCT05800834

NCT01675895

NCT01608373

NCT02454296

NCT05123170

NCT03171987

NCT06910644

NCT06268704

NCT02512783

NCT03119181

NCT06694714

NCT02607488

NCT06431165

NCT04733781

NCT04169854

NCT04194294

NCT06226532

NCT00590590

NCT04359017

NCT01608360

NCT05417425

NCT02291094

NCT04339049

NCT03808129

NCT06226415

NCT00848679

NCT04647084

NCT01539317

NCT03699995

NCT01391598

NCT03377907

NCT05914350

NCT00597766

NCT02510287

NCT02619981

NCT01245868

NCT00977028

NCT07536594

NCT04055116

NCT07337135

NCT01961739

NCT03794505

NCT06225323

NCT07648784

NCT06834854

NCT05289804

NCT02522130

NCT03870711

NCT02738203

NCT04659057

NCT07318285

NCT05470166

NCT01384877

NCT02912195

NCT04646707

NCT06974656

NCT06747390

NCT01425840

NCT04167176

NCT04518189

NCT04167189

NCT03809923

NCT01756443

NCT01425619

NCT03810235

NCT00811187

NCT06974019

NCT05051007

NCT01087489

NCT03300674

NCT06201039

NCT05481970

NCT00993746

NCT03636451

NCT00822133

NCT03792776

NCT00247741

NCT05928520

NCT07475520

NCT02121119

NCT05379283

NCT06379490

NCT02620501

NCT03531970

NCT00924963

NCT06910241

NCT04757740

NCT02240628

NCT06595017

NCT03637582

NCT04062357

NCT00566904

NCT01496105

NCT07408193

NCT00330941

NCT01744197

NCT07250867

NCT04518202

NCT05737121

NCT04472689

NCT03376178

NCT02620683

NCT01186549

NCT03189329

NCT00686231

NCT06584461

NCT02909140

NCT04260685

NCT05867342

NCT05336825

NCT04774029

NCT01945528

NCT02762656

NCT07203274

NCT03625076

NCT03301766

NCT00725504

NCT02025361

NCT03088371

NCT04505280

NCT02241460

NCT00727935

NCT05767827

NCT02241096

NCT04784728

NCT03012009

NCT03120923

NCT06648265

NCT05141864

NCT05624957

NCT05767749

NCT03624985

NCT01300377

NCT02524743

NCT07650396

NCT00913003

NCT02763592

NCT06493656

NCT02525016

NCT04162535

NCT04791020

NCT04517890

NCT05679765

NCT07202624

NCT04574947

NCT07550348

NCT03210038

NCT02452112

NCT02935972

NCT03028012

NCT03788018

NCT04814433

NCT04260659

NCT04506034

NCT02460627

NCT01126359

NCT03701984

NCT01944098

NCT06427707

NCT06310200

NCT01433328

NCT01964586

NCT07213037

NCT07141589

NCT07408414

NCT07401745

NCT06161714

NCT01794533

NCT01062906

NCT00747669

NCT02507440

NCT07089173

NCT01383200

NCT02039661

NCT02300038

NCT07248202

NCT01827020

NCT04369950

NCT01492179

NCT01027611

NCT02240407

NCT03968822

NCT04505657

NCT05750056

NCT07509918

NCT05909462

NCT04995497

NCT04645823

NCT02240199

NCT07683429

NCT06304870

NCT04706767

NCT06602349

NCT04505644

NCT07632144

NCT02023684

NCT04706897

NCT05243940

NCT06090955

NCT07068243

NCT05714631

NCT02904915

NCT06328205

NCT05143489

NCT03140293

NCT00589979

NCT04868747

NCT06761547

NCT06304779

NCT05414305

NCT02238288

NCT05614609

NCT03009500

NCT07092046

NCT00110773

NCT04201249

NCT04707183

NCT02387567

NCT03399474

NCT07630155

NCT03971708

NCT07629713

NCT05563571

NCT01330459

NCT00382499

NCT03640468

NCT01759459

NCT03030560

NCT04614610

NCT01759524

NCT02601651

NCT02114021

NCT00864682

NCT03530488

NCT07067541

NCT06661902

NCT04732455

NCT03871478

NCT02172729

NCT03620591

NCT00110760

NCT05318560

NCT06661967

NCT03031808

NCT06662318

NCT07552766

NCT04640896

NCT03781843

NCT02769247

NCT03530033

NCT00835939

NCT01342510

NCT05412576

NCT02902770

NCT07533643

NCT06999057

NCT03587220

NCT06497296

NCT00786916

NCT06967064

NCT06457100

NCT05732532

NCT05034406

NCT04377204

NCT03620513

NCT00382083

NCT02158039

NCT00110747

NCT05854082

NCT05866653

NCT01939743

NCT02770690

NCT03211455

NCT01508832

NCT04378283

NCT05560035

NCT03177252

NCT02734940

NCT03924791

NCT06272461

NCT02288364

NCT05667987

NCT05906615

NCT04732104

NCT02462915

NCT04378959

NCT04467424

NCT05238506

NCT06966102

NCT06965933

NCT01060774

NCT01240148

NCT03978845

NCT07709390

NCT01450566

NCT00613834

NCT00975910

NCT02088866

NCT04203225

NCT05936190

NCT07627100

NCT03778008

NCT03304431

NCT04467125

NCT03865940

NCT00110734

NCT06546254

NCT05148637

NCT06304090

NCT02623803

NCT00863889

NCT06121141

NCT02334176

NCT04150536

NCT07283874

NCT00308841

NCT06864078

NCT00992108

NCT07590830

NCT03527836

NCT01344252

NCT04149938

NCT06121466

NCT05150756

NCT01790464

NCT07000058

NCT02287870

NCT02022059

NCT02597699

NCT05732181

NCT05235256

NCT02505633

NCT01612156

NCT02597257

NCT05058677

NCT01602692

NCT03007420

NCT07259772

NCT05031078

NCT00058357

NCT01541293

NCT03560349

NCT05032508

NCT04148599

NCT03982862

NCT01996384

NCT04584749

NCT01824758

NCT03526874

NCT01394250

NCT01204242

NCT06220643

NCT00676364

NCT00309673

NCT02372786

NCT02895022

NCT02894710

NCT00991848

NCT01307839

NCT06865469

NCT00256542

NCT02252926

NCT03984045

NCT02344589

NCT01496846

NCT02020551

NCT02647385

NCT04609865

NCT01463280

NCT07145879

NCT05343299

NCT05234619

NCT02597140

NCT02733471

NCT01330134

NCT03984656

NCT06643832

NCT01360749

NCT06423456

NCT03308136

NCT05151510

NCT03143452

NCT03704584

NCT07000760

NCT05291221

NCT01214161

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NCT00851513

Known as 1% Lidocaine 1% LidocaineNCT02822196
Known as 2-(diethylamino)-N-(2.6-dimethylphenyl) acetamide “Lidocaine (or 2-(diethylamino)-N-(2.6-dimethylphenyl) acetamide) is the main prototype of amino-amide local anesthetics.” NCT06431165
Known as 4% liposomal lidocaine (Brand name = LMX4) 4% liposomal lidocaine (Brand name = LMX4)NCT00676364
Known as 5% lidocaine-medicated plaster 5% lidocaine-medicated plaster (LMP), which can block the Na+ channels on Aδ and C fibres” PMID 34341037 Aug 2021
Known as 5LP “comparing 5% lidocaine medicated plaster (5LP) and placebo whether neuropathic pain symptoms” NCT02763592
Known as Akten “The three topical anesthetics being studied are 1) 0.5% proparacaine hydrochloride (generic, Akorn, Inc), 2) 0.5% proparacaine hydrochloride (generic, Akorn, Inc) PLUS 4%...” NCT01027611
Known as ALGRX 3268 ALGRX 3268 (previously known as PowderJect® Dermal Lidocaine) is a system for needle-free, pain-free epidermal injection of lidocaine powder that provides local anesthesia...” NCT00132405
3

ALGRX 3268 (Previously known as PowderJect(R) Dermal Lidocaine) is used for local anesthesia within 3 minutes to provide painless needle or cathether insertion for blood drawing.” NCT00146185

NCT00140088

NCT00146185

Known as Alkalinized lidocaine Alkalinized lidocaine in the endotracheal tube (ETT) cuff decreases the incidence of cough and throat pain on emergence after surgery lasting more than 2 hours.” PMID 29189279 Feb 2018
Known as Anestol pomade(lidocaine) Anestol pomade(lidocaine)NCT05125796
Known as Aritmal “1 mL of triamcinolone acetonide 40 mg (KENACORT-A IM/Intra-articular Retard 40 mg ampoule) and 1 mL of 2% lidocaine (Aritmal 2% ampoule) will be injected over the plantar fascia.” NCT07120204
1

“a total of 4 mL of local anesthetic solution consisting of 2 mL of 0.5% bupivacaine and 2 mL of 2% lidocaine (Aritmal) will be injected on each side.” NCT07608861

Known as AritmalR “Retrobulbar block was performed with 5 ml of 2% lidocaine hydrochloride (AritmalR, Osel, Istanbul, Turkey) in Group L patients.” NCT03189329
Known as Aspercreme Aspercreme (Lidocaine Patch 4%)” NCT05106400
Known as Autologous PRP ClinicalTrials.gov intervention name — accepted as the source's own label NCT03026855
Known as Buffered Lidocaine “1% Buffered Lidocaine for injection, 0.50 mL administered one time intradermally in peripheral forearm” NCT01759459
3

Buffered Lidocaine (1% Lidocaine + 8.4% Sodium Bicarbonate, in a 3:1 ratio)” NCT06661902

“Drug: Buffered LidocaineNCT06974019

NCT02209272

Known as CNTX-2022 CNTX-2022 (lidocaine gel, 40%)” NCT02679339
Known as DEBOCAINE “This arm will receive lidocaine injection (Debocaine®, 2%, Sigma-Tec, Egypt) with a dose of 80-200 mg equivalent to 10 ml lidocaine (20 mg/ml) is injected at four and eight...” NCT03362905
2

“The lidocaine group will be administered a 1,000 ml distention medium containing 5 ml lidocaine per 250 ml (DEBOCAINE (LIDOCAINE) 2% 1 VIAL 50 ML, Sigma-Tec pharmaceutical...” NCT03701984

“Local infiltration with Lidocaine HCL 1%'Debocaine'” NCT05850455

Known as depocaine “5 mL of 2% lidocaine anhydrous solution (Depocaine) will be injected slowly along the lines of the edges of the perineal tears after delivery, with frequent aspirations to...” NCT02883179
Known as Diprophos ClinicalTrials.gov intervention name — accepted as the source's own label NCT02916940
Known as Drug: lidocaine hydrochloride Drug: lidocaine hydrochlorideNCT00693043
Known as Esracaine “Pad soaked with lidocaine gel (Esracaine) left on the introitus for 5 minutes” NCT03210038
Known as Experimental Group 1 triamcinolone and lidocaine ClinicalTrials.gov intervention name — accepted as the source's own label NCT03127137
Known as Hospira brand 1% Lidocaine in 20 mL vial Hospira brand 1% Lidocaine in 20 mL vialNCT01759459
Known as IV lidocaine IV lidocaineNCT01319682
Known as IVL “Intravenous lidocaine (IVL), an alternative to epidural analgesia (EA) for laparotomies, has demonstrated anti-inflammatory and anti-hyperalgesic effects.” PMID 41790838 Mar 2026
2

“Randomisation will be into group Control (C) and Lidocaine (IVL).” NCT03410836

“perioperative intravenous lidocaine (IVL)” NCT05541640