Intravenous Lidocaine for Treating Intrathecal Fentanyl Induced Pruritus

Phase 0 Unknown 54 enrolled Ain Shams University

RandomizedParallel-groupSingle-blindTreatment

Summary

The study will assess efficacy of intravenous lidocaine 1 mg/kg diluted with 0.9% sodium chloride to a volume of 100 ml to suppress intrathecal fentanyl induced pruritus. This will be compared to control group who will receive 100 ml normal saline as placebo. The main outcome is regression of initial VAS score with incidence of pruritus.

Timeline

Start: 2024-03-01
Primary completion: 2024-09-01
Completion: 2024-10-01

Publications

Background Wang J, Li J, Cao H, Zhou X, Tang Q. Intravenous lidocaine suppresses dexamethasone-induced perineal pruritus during anesthesia induction: a randomized controlled, double blind study. Pak J Pharm Sci. 2015 Mar;28(2):569-72.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lidocaine	Other / unclassified	1 mg/kg	Intravenous

Indications

No indication recorded.