drugset / Trial / NCT04162535
Elucidation of the Mechanisms and Effects of Certain Anesthetic Interventions on Digestive Cancer Patients Subjected to Surgery
Phase 1
Unknown
40 enrolled
Iuliu Hatieganu University of Medicine and Pharmacy
Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor · collabProf. Dr. I. Chiricuta Institute of Oncology · collab
RandomizedParallel-groupSingle-blindBasic science
Summary
Digestive cancers (liver, colonic, pancreatic) have a high incidence and high mortality, their population prevalence is also increasing. Given that the anesthesia techniques and the agents used act directly and indirectly on the immune system during the perioperative period, influencing both the treatment and the prognosis of patients with colorectal cancer who undergo elective interventions, a series of perianesthetic interventions have been proposed in order to reduce morbidity-mortality perioperative.
Timeline
- Start
- 2018-11-26
- Primary completion
- 2023-12-31
- Completion
- 2023-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lidocaine | Other / unclassified | 2 mg/kg | Intravenous |
| Subject | Propofol | Small molecule | — | Intravenous |
| Subject | Sevoflurane | Other / unclassified | — | — |