Sevoflurane
Other / unclassified targets KCNK10, KCNK18, KCNK2, KCNK3, KCNK9 via activation
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | ULTANE | — | 2001-03-30 | fda.gov ↗ |
| Approved | US (FDA) | ULTANE | — | 1995-06-07 | fda.gov ↗ |
Trials 232 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 07 trials | ||||||
| Phase 0 | NCT06626711 | Oct 2024 → Nov 2025 overdue | cancer | Saint Petersburg State University, Russia | Active not recruiting | No outcome recorded |
| Phase 0 | NCT06044740 | Jan 2024 → Jan 2026 | amnestic disorder | Keith M Vogt | Completed | No outcome recorded |
| Phase 0 | NCT04950205 | Jun 2021 → Dec 2022 | arterial disorder, subjective cognitive decline | Second Affiliated Hospital, School of Medicine, Zhejiang University | Unknown | No outcome recorded |
| Phase 0 | NCT04998253 | Oct → Nov 2020 | COVID-19, acute respiratory distress syndrome | Unidad Temporal COVID-19 en Centro Citibanamex | Completed | No outcome recorded |
| Phase 0 | NCT03498235 | Mar 2018 → Jun 2020 | — | Obstetrics & Gynecology Hospital of Fudan University | Unknown | No outcome recorded |
| Phase 0 | NCT02149927 | Jun → Dec 2013 | drug-induced mental disorder | Technical University of Munich | Completed | No outcome recorded |
| Phase 0 | NCT01511991 | May 2009 → May 2014 | heart valve disorder | Konkuk University Medical Center | Completed | No outcome recorded |
| Phase 16 trials | ||||||
| Phase 1 | NCT05742789 | Nov 2021 → Jan 2023 | aortic valve insufficiency, mitral valve insufficiency | Astana Medical University | Completed | No outcome recorded |
| Phase 1 | NCT05695287 | Jan 2021 → Nov 2022 | aortic valve insufficiency, coronary artery disorder, mitral valve insufficiency | Astana Medical University | Completed | No outcome recorded |
| Phase 1 | NCT04162535 | Nov 2018 → Dec 2023 | colorectal cancer | Iuliu Hatieganu University of Medicine and Pharmacy | Unknown | No outcome recorded |
| Phase 1 | NCT03569085 | Jun → Dec 2018 | heart disorder | Kathirvel Subramaniam | Completed | No outcome recorded |
| Phase 1 | NCT03311581 | Sep 2017 → Jun 2021 | end stage renal failure | Kaohsiung Medical University Chung-Ho Memorial Hospital | Completed | No outcome recorded |
| Phase 1 | NCT02188407 | Jul 2008 → Sep 2013 | — | University Medical Centre Ljubljana | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT04771962 | Jan 2020 → Dec 2021 | — | Universiti Sains Malaysia | Completed | No outcome recorded |
| Phase 1/2 | NCT02918877 | Jun 2017 → Dec 2018 | acute lung injury | Beth Israel Deaconess Medical Center | Completed | No outcome recorded |
| Phase 1/2 | NCT00484575 | Jun 2007 → Oct 2008 | atrial fibrillation, myocardial disorder | Karolinska Institutet | Completed | No outcome recorded |
| Phase 213 trials | ||||||
| Phase 2 | NCT03643367 | Jan 2026 → Feb 2027 expected | — | University of Zurich | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT03503578 | May → Aug 2018 | — | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT02839668 | Aug 2016 → Sep 2019 | breast cancer | Iuliu Hatieganu University of Medicine and Pharmacy | Completed | No outcome recorded |
| Phase 2 | NCT02946437 | Nov 2015 → Dec 2019 | acquired aneurysmal subarachnoid hemorrhage | University of Zurich | Withdrawn | No outcome recorded |
| Phase 2 | NCT02202720 | Aug → Nov 2014 | — | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| Phase 2 | NCT02042599 | Jan 2014 → Feb 2016 | acute kidney injury | University Hospital, Clermont-Ferrand | Unknown | No outcome recorded |
| Phase 2 | NCT02048683 | Dec 2013 → Sep 2015 | — | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| Phase 2 | NCT02042612 | Oct 2013 → Jan 2014 | obesity disorder | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| Phase 2 | NCT02284204 | Jan 2012 → Aug 2014 | — | Federal University of Goiás | Completed | No outcome recorded |
| Phase 2 | NCT01374633 | Dec 2011 → Mar 2013 | brain injury | Assistance Publique - Hôpitaux de Paris | Terminated | No outcome recorded |
| Phase 2 | NCT00522587 | Apr 2008 → Jul 2009 | — | University Hospital, Ghent | Completed | No outcome recorded |
| Phase 2 | NCT00535808 | Oct 2007 → Mar 2011 | — | University Hospital, Ghent | Completed | No outcome recorded |
| Phase 2 | NCT00000261 | Nov 1997 → Oct 1998 | alcohol-related disorders | University of Chicago | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT00420693 | Aug 2006 → May 2008 | — | Assistance Publique Hopitaux De Marseille | Completed | No outcome recorded |
| Phase 323 trials | ||||||
| Phase 3 | NCT07166991 | Feb 2026 → Sep 2028 expected | — | University Hospital, Grenoble | Recruiting | No outcome recorded |
| Phase 3 | NCT05849779 | Jul 2023 → May 2026 overdue | acute respiratory distress syndrome | University Hospital, Clermont-Ferrand | Recruiting | No outcome recorded |
| Phase 3 | NCT05615025 | Jan → Jun 2023 | neuromuscular junction disease | Brugmann University Hospital | Completed | No outcome recorded |
| Phase 3 | NCT05259631 | Mar 2022 → Feb 2025 | adult acute respiratory distress syndrome | Negovsky Reanimatology Research Institute | Suspended | No outcome recorded |
| Phase 3 | NCT04530188 | Nov 2020 → May 2022 | acute respiratory distress syndrome | Bicetre Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04415060 | Jun 2020 → Mar 2026 overdue | COVID-19, respiratory failure | Sunnybrook Health Sciences Centre | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04235608 | May 2020 → Oct 2023 | acute respiratory distress syndrome | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| Phase 3 | NCT04355962 | Apr 2020 → Jun 2021 | COVID-19, acute respiratory distress syndrome | University of Zurich | Completed | No outcome recorded |
| Phase 3 | NCT03841812 | Jan → Jun 2020 | — | China International Neuroscience Institution | Completed | No outcome recorded |
| Phase 3 | NCT05696509 | Jan 2020 → Oct 2022 | aortic valve insufficiency, mitral valve insufficiency | Astana Medical University | Completed | No outcome recorded |
| Phase 3 | NCT03588429 | Jan → Aug 2020 | — | Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine | Completed | No outcome recorded |
| Phase 3 | NCT03089905 | Aug 2017 → Mar 2026 overdue | poisoning | Murdoch Childrens Research Institute | Active not recruiting | No outcome recorded |
| Phase 3 | NCT03022240 | Jan 2017 → Sep 2019 | — | University of Calgary | Completed | No outcome recorded |
| Phase 3 | NCT02872389 | Aug → Dec 2016 | — | Kangbuk Samsung Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02830243 | Jul → Oct 2016 | — | Kangbuk Samsung Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02698514 | Feb → Jul 2016 | — | Kangbuk Samsung Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02609802 | Nov 2015 → Jul 2016 | musculoskeletal system disorder | Kangbuk Samsung Hospital | Completed | No outcome recorded |
| Phase 3 | NCT01802255 | Mar 2013 → Jan 2015 | poisoning | F Javier Belda | Withdrawn | No outcome recorded |
| Phase 3 | NCT01006668 | Nov 2009 → Nov 2014 | — | Assistance Publique Hopitaux De Marseille | Unknown | No outcome recorded |
| Phase 3 | NCT00741351 | Dec 2007 → Mar 2009 | — | Azienda Ospedaliera San Gerardo di Monza | Completed | No outcome recorded |
| Phase 3 | NCT00559468 | Dec 2006 → Mar 2007 | — | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 3 | NCT00389883 | Nov 2006 → Jan 2010 | supratentorial cancer | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT00337051 | Jun 2006 → Feb 2010 | acute kidney injury, end stage renal failure | University Hospital, Bordeaux | Completed | No outcome recorded |
| Phase 470 trials | ||||||
| Phase 4 | NCT07123870 | Jul → Oct 2025 overdue | — | Kocaeli City Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07673003 | Jun → Nov 2025 | — | Children's Hospital and Institute of Child Health, Multan | Completed | No outcome recorded |
| Phase 4 | NCT06779890 | May 2025 → Sep 2026 expected | brain edema | Georgia Tsaousi | Recruiting | No outcome recorded |
| Phase 4 | NCT06773351 | Feb → Dec 2025 overdue | — | Feng Gao | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06560268 | Nov 2024 → Jun 2025 overdue | delirium, strabismus | Cukurova University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07080528 | Jul 2024 → Aug 2025 overdue | curariform drugs toxicity | Tamas Vegh, MD | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT06371638 | Jan → Mar 2024 | — | Udayana University | Completed | No outcome recorded |
| Phase 4 | NCT05941494 | Oct 2023 → Dec 2025 | — | Jason Chui | Unknown | No outcome recorded |
| Phase 4 | NCT05926336 | May 2023 → Jul 2026 overdue | brain neoplasm, liver cancer, lung cancer, ovarian cancer | Kaohsiung Medical University Chung-Ho Memorial Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT05822817 | May 2023 → Apr 2024 | pituitary gland adenoma | Peking Union Medical College Hospital | Completed | No outcome recorded |
| Phase 4 | NCT05369949 | Jan 2023 → Dec 2025 | congenital heart disease | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Unknown | No outcome recorded |
| Phase 4 | NCT05663242 | Dec 2022 → Nov 2026 expected | lung cancer | Kaohsiung Medical University Chung-Ho Memorial Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT05303805 | May 2022 → Apr 2026 overdue | ulcer of lower limbs | Charles University, Czech Republic | Recruiting | No outcome recorded |
| Phase 4 | NCT05331911 | Apr 2022 → Dec 2026 expected | hepatocellular carcinoma | Kaohsiung Medical University Chung-Ho Memorial Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT05158998 | Mar 2022 → Nov 2024 | delirium | Qianfoshan Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT05141877 | Feb 2022 → Nov 2024 | primary brain neoplasm | Kaohsiung Medical University Chung-Ho Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT05996588 | Jan → Nov 2022 | — | Sindh Institute of Urology and Transplantation | Completed | No outcome recorded |
| Phase 4 | NCT04874545 | Jun → Dec 2021 | central hearing loss, cognitive disorder | Beni-Suef University | Completed | No outcome recorded |
| Phase 4 | NCT04802122 | May → Jul 2021 | — | Aristotle University Of Thessaloniki | Completed | No outcome recorded |
| Phase 4 | NCT04839536 | Apr 2021 → Mar 2022 | chronic kidney disease | University of Malaya | Unknown | No outcome recorded |
| Phase 4 | NCT04443946 | Jun → Aug 2020 | — | China International Neuroscience Institution | Completed | No outcome recorded |
| Phase 4 | NCT04435834 | Jun 2020 → Sep 2026 expected | — | Matthew Borzage | Recruiting | No outcome recorded |
| Phase 4 | NCT04346823 | May 2020 → Mar 2021 | uterine disorder | King Saud University | Unknown | No outcome recorded |
| Phase 4 | NCT04359862 | Apr 2020 → Mar 2021 | COVID-19, acute respiratory distress syndrome | Fundación para la Investigación del Hospital Clínico de Valencia | Terminated | No outcome recorded |
| Phase 4 | NCT04289090 | Jan 2020 → Jan 2022 | — | State University of New York - Downstate Medical Center | Unknown | No outcome recorded |
| Phase 4 | NCT04014218 | Jan → Sep 2019 | acute respiratory distress syndrome | Moscow Regional Research and Clinical Institute (MONIKI) | Unknown | No outcome recorded |
| Phase 4 | NCT03595319 | Jul → Oct 2018 | hypotensive disorder | Brasilia University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03209193 | Jul 2017 → Nov 2019 | — | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03772106 | Jun 2017 → Jan 2018 | — | University Hospital, Ghent | Completed | No outcome recorded |
| Phase 4 | NCT03149588 | Apr 2017 → Sep 2019 | — | Tao Zhang | Unknown | No outcome recorded |
| Phase 4 | NCT03034096 | Jan 2017 → Sep 2024 | — | Stony Brook University | Completed | No outcome recorded |
| Phase 4 | NCT02931877 | Oct 2016 → Apr 2018 | subjective cognitive decline | Xinqiao Hospital of Chongqing | Completed | No outcome recorded |
| Phase 4 | NCT03215446 | Jun 2016 → May 2018 | — | Centre Hospitalier Universitaire Dijon | Completed | No outcome recorded |
| Phase 4 | NCT02834845 | Jun → Aug 2016 | — | Ufuk University | Completed | No outcome recorded |
| Phase 4 | NCT02748265 | Mar 2016 → Jul 2017 | — | University Health Network, Toronto | Completed | No outcome recorded |
| Phase 4 | NCT02671084 | Feb 2016 → Apr 2020 | myocardial infarction | Instituto Dante Pazzanese de Cardiologia | Terminated | No outcome recorded |
| Phase 4 | NCT02624401 | Jan 2016 → Mar 2017 | — | University of Turku | Completed | No outcome recorded |
| Phase 4 | NCT02851433 | Oct 2015 → Aug 2017 | cardiac valvular defect | Centre Hospitalier Universitaire Dijon | Completed | No outcome recorded |
| Phase 4 | NCT02609087 | Aug 2015 → Dec 2016 | carotid stenosis | Chonnam National University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02146976 | Oct 2014 → Sep 2015 | — | China Medical University, China | Completed | No outcome recorded |
| Phase 4 | NCT03134677 | Jul 2014 → Jul 2016 | — | Trakya University | Completed | No outcome recorded |
| Phase 4 | NCT02105610 | Apr 2014 → Oct 2017 | — | Vita-Salute San Raffaele University | Completed | No outcome recorded |
| Phase 4 | NCT02166853 | Apr 2014 → Feb 2016 | acute respiratory distress syndrome | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| Phase 4 | NCT02110745 | Mar → Nov 2014 | cryptorchidism | Mustafa Kemal University | Completed | No outcome recorded |
| Phase 4 | NCT02005770 | Mar 2014 → Apr 2018 | female breast carcinoma | University of Zurich | Completed | No outcome recorded |
| Phase 4 | NCT02107170 | Feb 2014 → Oct 2017 | arteriosclerosis obliterans | Tao Zhang | Completed | No outcome recorded |
| Phase 4 | NCT01995214 | Jun → Dec 2013 | — | Huazhong University of Science and Technology | Unknown | No outcome recorded |
| Phase 4 | NCT01930747 | Apr 2013 → Dec 2015 | — | AZ Sint-Jan AV | Completed | No outcome recorded |
| Phase 4 | NCT01809041 | Mar 2013 → Apr 2019 | — | Sun Yat-sen University | Completed | No outcome recorded |
| Phase 4 | NCT02054143 | Nov 2012 → Apr 2013 | — | University of Debrecen | Completed | No outcome recorded |
| Phase 4 | NCT02168751 | Sep 2012 → Jun 2014 | — | Hospital General Universitario Gregorio Marañon | Completed | No outcome recorded |
| Phase 4 | NCT02664922 | May 2012 → Sep 2013 | heart disorder | University of California, Los Angeles | Terminated | No outcome recorded |
| Phase 4 | NCT01662622 | Mar → May 2012 | — | Huazhong University of Science and Technology | Completed | No outcome recorded |
| Phase 4 | NCT01477151 | Nov 2011 → Mar 2015 | coronary artery disorder, heart valve disorder | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Completed | No outcome recorded |
| Phase 4 | NCT01189721 | Aug 2010 → Jul 2011 | — | Gangnam Severance Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01092923 | Oct 2009 → Jul 2010 | — | Austin Health | Completed | No outcome recorded |
| Phase 4 | NCT01084200 | Sep 2009 → Jan 2010 | — | Huazhong University of Science and Technology | Completed | No outcome recorded |
| Phase 4 | NCT01437462 | Oct 2008 → Mar 2013 | female reproductive system disorder | Tampere University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01096212 | Sep 2008 → Sep 2009 | — | Asan Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00821262 | Sep 2008 → Jul 2011 | cardiac valvular defect | Vita-Salute San Raffaele University | Completed | No outcome recorded |
| Phase 4 | NCT00665418 | Feb → Aug 2008 | laryngeal disorder | University Hospital, Basel, Switzerland | Terminated | No outcome recorded |
| Phase 4 | NCT00541918 | Jun 2007 → Apr 2015 | cognitive disorder, heart disorder | Medical University of Gdansk | Withdrawn | No outcome recorded |
| Phase 4 | NCT00336401 | Oct 2006 → Feb 2008 | — | University Health Network, Toronto | Completed | No outcome recorded |
| Phase 4 | NCT00477737 | Aug → Dec 2006 | coronary artery disorder | University Hospital Dubrava | Completed | No outcome recorded |
| Phase 4 | NCT00244283 | Jan 2006 → Jan 2008 | — | Golden Jubilee National Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT00569816 | Jan 2005 → May 2007 | — | University Hospital Schleswig-Holstein | Completed | No outcome recorded |
| Phase 4 | NCT00364637 | Jan 2005 → Aug 2024 | — | Vita-Salute San Raffaele University | Completed | No outcome recorded |
| Phase 4 | NCT00526695 | Jan 2005 → Dec 2008 | ischemic disease | University of Zurich | Unknown | No outcome recorded |
| Phase 4 | NCT02785653 | Apr 2004 → Nov 2006 | — | Maharashtra University of Health Sciences | Completed | No outcome recorded |
| Phase 4 | NCT00144118 | Jan 2002 → Aug 2005 | kidney failure | Austin Health | Terminated | No outcome recorded |
| Phase not applicable109 trials | ||||||
| — | NCT07601256 | Aug 2026 → Dec 2030 expected | infectious disease with sepsis, lung disorder | Sixth Affiliated Hospital, Sun Yat-sen University | Not yet recruiting | No outcome recorded |
| — | NCT07608900 | Aug 2026 → Aug 2027 expected | — | TC Erciyes University | Not yet recruiting | No outcome recorded |
| — | NCT07620782 | May 2026 → Apr 2027 expected | — | Pusan National University Yangsan Hospital | Recruiting | No outcome recorded |
| — | NCT07295158 | Mar → Jul 2026 overdue | — | Konya City Hospital | Recruiting | No outcome recorded |
| — | NCT07325669 | Jan 2026 → Jan 2027 expected | — | dilara gocmen | Not yet recruiting | No outcome recorded |
| — | NCT07192549 | Sep 2025 → Sep 2030 expected | delirium | General Hospital of Ningxia Medical University | Not yet recruiting | No outcome recorded |
| — | NCT07152912 | Sep 2025 → Mar 2026 overdue | Halothane hepatitis, disorder of defective peroxisome oxidative status, gallbladder disorder | Ain Shams University | Recruiting | No outcome recorded |
| — | NCT06907823 | Jun → Dec 2025 overdue | — | Pusan National University Yangsan Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07611240 | Jun 2025 → Jun 2026 overdue | obesity disorder | Ataturk University | Recruiting | No outcome recorded |
| — | NCT07016308 | Jun → Nov 2025 | — | Harran University | Completed | No outcome recorded |
| — | NCT06788743 | Jun 2025 → Apr 2026 overdue | delirium, diabetes mellitus | Xijing Hospital | Recruiting | No outcome recorded |
| — | NCT07035782 | Jun 2025 → May 2026 overdue | cold-induced sweating syndrome - hyperthermia spectrum | Second Affiliated Hospital of Wenzhou Medical University | Not yet recruiting | No outcome recorded |
| — | NCT07450495 | Feb 2025 → Feb 2026 overdue | chalazion | Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong | Recruiting | No outcome recorded |
| — | NCT07062367 | Feb 2025 → Feb 2027 expected | — | Tanta University | Recruiting | No outcome recorded |
| — | NCT07378878 | Feb → May 2025 | — | Universitas Sumatera Utara | Completed | No outcome recorded |
| — | NCT06759623 | Jan 2025 → Apr 2026 overdue | obesity disorder | Medical University of Gdansk | Recruiting | No outcome recorded |
| — | NCT07248917 | Oct 2024 → Jun 2025 | Halothane hepatitis, urolithiasis | Dr. Lutfi Kirdar Kartal Training and Research Hospital | Completed | No outcome recorded |
| — | NCT06601036 | Sep 2024 → Feb 2025 overdue | — | Tanta University | Recruiting | No outcome recorded |
| — | NCT06390046 | Apr → Dec 2024 | — | Jagiellonian University | Completed | No outcome recorded |
| — | NCT06396468 | Mar → Jun 2024 | subacute delirium | Benha University | Unknown | No outcome recorded |
| — | NCT06423846 | Jan → May 2024 | — | Benha University | Completed | No outcome recorded |
| — | NCT06210061 | Jan 2024 → Mar 2025 | — | Ain Shams University | Completed | No outcome recorded |
| — | NCT05936671 | Jul 2023 → Jun 2025 overdue | — | Gangnam Severance Hospital | Recruiting | No outcome recorded |
| — | NCT07665645 | Jan → Jun 2023 | obesity disorder | Gaziantep City Hospital | Completed | No outcome recorded |
| — | NCT05639686 | Jan 2023 → Dec 2024 | cephalocele, chronic rhinosinusitis, paranasal sinus carcinoma, polyp | Our Lady of the Lake Hospital | Unknown | No outcome recorded |
| — | NCT03763305 | Jan → Dec 2023 | — | Seoul National University Hospital | Withdrawn | No outcome recorded |
| — | NCT05505123 | Aug → Dec 2022 | cerebral palsy | Yeungnam University College of Medicine | Withdrawn | No outcome recorded |
| — | NCT05396690 | Jun 2022 → May 2023 | — | Ajou University School of Medicine | Unknown | No outcome recorded |
| — | NCT04800393 | Mar 2022 → Jul 2023 overdue | breast cancer | Moscow Clinical Scientific Center | Recruiting | No outcome recorded |
| — | NCT05693428 | Jan → Nov 2022 | coronary artery disorder | Astana Medical University | Completed | No outcome recorded |
| — | NCT05019222 | Sep 2021 → Aug 2022 | atlanto-axial fusion | Gangnam Severance Hospital | Completed | No outcome recorded |
| — | NCT04965532 | Sep 2021 → Feb 2022 | chemotherapy-induced toxicity | Second Affiliated Hospital, School of Medicine, Zhejiang University | Unknown | No outcome recorded |
| — | NCT05008939 | Aug 2021 → Mar 2022 | major depressive disorder | Shanghai First Maternity and Infant Hospital | Unknown | No outcome recorded |
| — | NCT04725032 | Jan 2021 → Dec 2025 | brain neoplasm | Beijing Tiantan Hospital | Unknown | No outcome recorded |
| — | NCT04364945 | Jun 2020 → May 2028 expected | toxic encephalopathy | Seoul National University Hospital | Active not recruiting | No outcome recorded |
| — | NCT04123249 | May → Nov 2020 | — | Yanchao Yang | Completed | No outcome recorded |
| — | NCT04680650 | Apr 2020 → Mar 2021 | nodular goiter | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | Unknown | No outcome recorded |
| — | NCT04292457 | Mar 2020 → Dec 2023 | delirium | Helse Nord-Trøndelag HF | Completed | No outcome recorded |
| — | NCT04292561 | Mar 2020 → Jan 2023 | delirium | The First Affiliated Hospital of Anhui Medical University | Completed | No outcome recorded |
| — | NCT04023305 | Feb 2020 → Dec 2021 | acute respiratory distress syndrome | University Hospital, Clermont-Ferrand | Terminated | No outcome recorded |
| — | NCT03830086 | Feb → Apr 2019 | — | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Completed | No outcome recorded |
| — | NCT03772054 | Dec 2018 → Dec 2019 | ischemic disease | University of Chile | Completed | No outcome recorded |
| — | NCT03701529 | Oct 2018 → Sep 2019 | leiomyoma, uterine cancer | Hallym University Kangnam Sacred Heart Hospital | Completed | No outcome recorded |
| — | NCT03553446 | Jul 2018 → Mar 2021 | — | Yeungnam University College of Medicine | Completed | No outcome recorded |
| — | NCT03587779 | Jul 2018 → Jan 2019 | — | Kangbuk Samsung Hospital | Completed | No outcome recorded |
| — | NCT03570164 | Jun → Nov 2018 | — | Kangbuk Samsung Hospital | Completed | No outcome recorded |
| — | NCT03539003 | May 2018 → Jan 2019 | — | Yonsei University | Completed | No outcome recorded |
| — | NCT05951842 | Apr 2018 → Feb 2020 | colorectal cancer | Gangnam Severance Hospital | Withdrawn | No outcome recorded |
| — | NCT03559920 | Apr 2018 → Mar 2019 | — | Yonsei University | Completed | No outcome recorded |
| — | NCT03510013 | Apr → May 2018 | — | Khon Kaen University | Completed | No outcome recorded |
| — | NCT03460015 | Mar 2018 → Sep 2020 | chronic obstructive pulmonary disease | University Hospital, Montpellier | Terminated | No outcome recorded |
| — | NCT03595163 | Jan → Apr 2018 | hearing loss disorder | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | Unknown | No outcome recorded |
| — | NCT03522402 | Jan 2018 | — | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | Unknown | No outcome recorded |
| — | NCT05004545 | Jun 2017 → Sep 2021 | — | Chaudhry Pervaiz Elahi Institute of Cardiology | Unknown | No outcome recorded |
| — | NCT03173339 | Jun → Aug 2017 | — | Keimyung University Dongsan Medical Center | Completed | No outcome recorded |
| — | NCT03129009 | Apr 2017 → Jun 2018 | intracerebral hemorrhage | Xuzhou Medical University | Unknown | No outcome recorded |
| — | NCT03024840 | Dec 2016 → May 2017 | — | Tianjin First Central Hospital | Unknown | No outcome recorded |
| — | NCT03165396 | Nov 2016 → Aug 2018 | cognitive disorder | The Third Central Clinical College of Tianjin Medical University | Unknown | No outcome recorded |
| — | NCT02916147 | Oct 2016 → Nov 2018 | non-small cell lung carcinoma | Tianjin Medical University Cancer Institute and Hospital | Unknown | No outcome recorded |
| — | NCT04284644 | May 2016 → Jan 2017 | — | University of Jordan | Completed | No outcome recorded |
| — | NCT02567942 | Feb 2016 → Apr 2018 | colon carcinoma | Konkuk University Medical Center | Completed | No outcome recorded |
| — | NCT03818048 | Jan → Oct 2016 | — | Centro Medico Docente la Trinidad | Completed | No outcome recorded |
| — | NCT03162861 | Jan 2016 → Jun 2017 | arthropathy | Qinghai University | Unknown | No outcome recorded |
| — | NCT02407626 | Sep 2015 → Mar 2018 | myocardial ischemia | Triemli Hospital | Terminated | No outcome recorded |
| — | NCT02711280 | Sep 2015 → Mar 2016 | — | First Affiliated Hospital, Sun Yat-Sen University | Completed | No outcome recorded |
| — | NCT02510586 | Aug 2015 → Aug 2018 | Moyamoya disease | Seoul National University Hospital | Unknown | No outcome recorded |
| — | NCT02489734 | Jul → Sep 2015 | delirium | Children's Hospital of Fudan University | Completed | No outcome recorded |
| — | NCT02711917 | Jul → Dec 2015 | — | Tianjin Medical University General Hospital | Completed | No outcome recorded |
| — | NCT02664142 | Jun 2015 → Sep 2017 | — | University Hospital Ostrava | Completed | No outcome recorded |
| — | NCT02470442 | Jun 2015 → Feb 2016 | — | Seoul National University Hospital | Completed | No outcome recorded |
| — | NCT03860129 | Dec 2014 → May 2017 | — | Ruhr University of Bochum | Completed | No outcome recorded |
| — | NCT02252445 | Nov 2014 → Jan 2015 | urinary bladder neoplasm | Seoul National University Hospital | Completed | No outcome recorded |
| — | NCT02342509 | Sep → Dec 2014 | — | Ruhr University of Bochum | Completed | No outcome recorded |
| — | NCT02920749 | Sep 2014 → Oct 2016 | — | University of Pecs | Completed | No outcome recorded |
| — | NCT02201134 | Jul 2014 → Dec 2017 | cardiac arrest | University Hospital, Clermont-Ferrand | Completed | No outcome recorded |
| — | NCT02419547 | Jul 2014 → Apr 2015 | ventricular tachycardia | Brigham and Women's Hospital | Completed | No outcome recorded |
| — | NCT02185118 | Jun 2014 → Jun 2018 | infectious disease with sepsis | Air Force Military Medical University, China | Unknown | No outcome recorded |
| — | NCT02096224 | May → Jul 2014 | urinary bladder neoplasm | Seoul National University Hospital | Completed | No outcome recorded |
| — | NCT02382445 | Jan 2014 → May 2017 | delirium, dementia | Heidelberg University | Completed | No outcome recorded |
| — | NCT01872884 | Nov 2013 → Sep 2016 | ischemic stroke | Sahlgrenska University Hospital | Completed | No outcome recorded |
| — | NCT02410460 | Sep 2013 → Jun 2014 | — | Mercy Facial Plastic Surgery Center | Completed | No outcome recorded |
| — | NCT03100604 | Aug 2013 → Mar 2016 | ear malformation | Trakya University | Completed | No outcome recorded |
| — | NCT01866657 | Jun 2013 → Nov 2016 | brain hypoxia - ischemia | University Hospitals Cleveland Medical Center | Terminated | No outcome recorded |
| — | NCT01851005 | May 2013 → Feb 2014 | — | Chosun University Hospital | Completed | No outcome recorded |
| — | NCT03112564 | Mar 2013 → Nov 2014 | — | Puerta de Hierro University Hospital | Completed | No outcome recorded |
| — | NCT01905501 | Feb 2013 → Sep 2014 | — | Regina Elena Cancer Institute | Completed | No outcome recorded |
| — | NCT03727464 | Jan 2013 → Sep 2016 | — | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | Completed | No outcome recorded |
| — | NCT01972230 | Jan 2013 → Apr 2015 | — | Regina Elena Cancer Institute | Completed | No outcome recorded |
| — | NCT01461551 | Oct 2011 → Feb 2012 | — | Ruijin Hospital | Completed | No outcome recorded |
| — | NCT01450956 | Sep 2011 → Jan 2012 | congenital heart disease | Xijing Hospital | Unknown | No outcome recorded |
| — | NCT01379664 | Jul 2011 → Apr 2013 | — | The Cleveland Clinic | Completed | No outcome recorded |
| — | NCT02151305 | Aug 2010 → Apr 2012 | cataract, keratitis, pterygium, retinal detachment | Seoul National University Bundang Hospital | Completed | No outcome recorded |
| — | NCT01171833 | Jun → Oct 2010 | — | DongGuk University | Completed | No outcome recorded |
| — | NCT00995670 | Mar 2010 → Sep 2013 | hyperglycemia | US Department of Veterans Affairs | Completed | No outcome recorded |
| — | NCT02806596 | Jan 2010 → Jun 2013 | — | University of Liege | Completed | No outcome recorded |
| — | NCT01083953 | Nov 2009 → Jul 2010 | — | University of Malaya | Completed | No outcome recorded |
| — | NCT02794896 | Mar 2009 → Mar 2012 | — | Heidelberg University | Completed | No outcome recorded |
| — | NCT00913276 | Jan 2009 → Aug 2012 | liver failure | University of Zurich | Completed | No outcome recorded |
| — | NCT00815269 | Dec 2008 → Dec 2009 | — | Nanjing Medical University | Completed | No outcome recorded |
| — | NCT00792779 | Nov 2008 → May 2009 | hemolytic anemia | Centro Medico Campinas | Unknown | No outcome recorded |
| — | NCT00733564 | Aug 2008 → Mar 2009 | uterine disorder | Nanjing Medical University | Completed | No outcome recorded |
| — | NCT00518908 | Jan 2008 → Aug 2010 | — | University of Zurich | Completed | No outcome recorded |
| — | NCT00924222 | Oct 2007 → Nov 2009 | — | University of Zurich | Completed | No outcome recorded |
| — | NCT00521612 | Sep → Nov 2007 | — | General Hospital Dubrovnik | Completed | No outcome recorded |
| — | NCT01001585 | Sep 2006 → Sep 2011 | mitochondrial disease | d sessler | Terminated | No outcome recorded |
| — | NCT00516711 | Mar 2006 → Dec 2007 | — | University of Zurich | Completed | No outcome recorded |
| — | NCT00775879 | Mar 2006 → Jul 2008 | — | University Hospital, Bordeaux | Completed | No outcome recorded |
| — | NCT00515905 | Oct 2004 → Sep 2007 | — | University of Zurich | Completed | No outcome recorded |
| — | NCT00434382 | Oct 2002 → Dec 2003 | — | Ludwig-Maximilians - University of Munich | Unknown | No outcome recorded |
Also used as a comparator or background therapy in 352 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 03 trials | ||||||
| Phase 0 | NCT05993039 Comparator | Sep 2023 → Dec 2024 | auditory system disorder | Our Lady of the Lake Hospital | Unknown | No outcome recorded |
| Phase 0 | NCT04016740 Background | Aug 2019 → Feb 2020 | coronary artery disorder, delirium | Beth Israel Deaconess Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT02786329 Comparator | Jun 2016 → Aug 2022 | colorectal cancer | Regional Institute of Gastroenterology and Hepatology Prof. Dr. Octavian Fodor | Unknown | No outcome recorded |
| Phase 14 trials | ||||||
| Phase 1 | NCT05025397 Background | Sep 2021 → Mar 2022 | — | Takeda | Completed | No outcome recorded |
| Phase 1 | NCT02973958 Background | Feb 2017 → Jun 2018 | balanitis, neuropathy, painful, paraphimosis | Alberta Children's Hospital | Completed | No outcome recorded |
| Phase 1 | NCT02571426 Comparator | Oct 2015 → Mar 2018 | kidney failure | Uppsala University | Completed | No outcome recorded |
| Phase 1 | NCT02229201 Comparator | May 2010 → Dec 2013 | — | University Medical Centre Ljubljana | Completed | No outcome recorded |
| Phase 1/24 trials | ||||||
| Phase 1/2 | NCT02429076 Background | Jun 2017 → Jul 2019 | — | Massachusetts General Hospital | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT02065947 Comparator | Oct 2013 → Mar 2014 | — | Ramathibodi Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT01700907 Comparator | Aug 2012 → Feb 2013 | — | Sapporo Medical University | Completed | No outcome recorded |
| Phase 1/2 | NCT01216007 Comparator | Oct 2010 → Oct 2012 | — | University of British Columbia | Completed | No outcome recorded |
| Phase 215 trials | ||||||
| Phase 2 | NCT06017141 Comparator | May 2023 → May 2025 | colon adenocarcinoma | University of Kansas Medical Center | Unknown | No outcome recorded |
| Phase 2 | NCT04646967 Background | Nov 2022 → Jan 2024 | balanitis, neuropathy, painful, paraphimosis | Alberta Children's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT04426552 Comparator | Jun → Sep 2020 | craniofacial and skeletal defects | Alexandria University | Unknown | No outcome recorded |
| Phase 2 | NCT03448068 Background | Apr 2018 → Jan 2020 | — | Mayo Clinic | Completed | No outcome recorded |
| Phase 2 | NCT02971254 Comparator | Dec 2016 → Jan 2019 | Down syndrome | Asklepieion Voulas General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT02877238 Comparator | Aug 2016 → May 2017 | congenital heart disease | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT03373266 Comparator | Oct 2015 → Aug 2017 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT02559297 Comparator | Aug 2015 → Jun 2017 | — | Mahidol University | Completed | No outcome recorded |
| Phase 2 | NCT02416063 Comparator | Jan → Oct 2014 | — | University of Jordan | Completed | No outcome recorded |
| Phase 2 | NCT01937767 Comparator | Aug 2013 → Feb 2014 | — | Paion UK Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT01757106 Comparator | Dec 2012 → Jul 2013 | coronary artery disorder | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| Phase 2 | NCT01701778 Background | Oct 2012 → Jan 2014 | cryptorchidism | Yao Yusheng | Completed | No outcome recorded |
| Phase 2 | NCT01691690 Background | Oct 2012 → Nov 2015 | tonsillitis | Nationwide Children's Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01199276 Comparator | Sep 2010 → Oct 2014 | delirium | Air Liquide | Completed | No outcome recorded |
| Phase 2 | NCT00971607 Comparator | May 2009 → Dec 2013 | acute myocardial infarction | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Completed | No outcome recorded |
| Phase 2/35 trials | ||||||
| Phase 2/3 | NCT05636566 Comparator | Feb → Sep 2022 | childhood malignant neoplasm, invasive carcinoma | Alexandria University | Completed | No outcome recorded |
| Phase 2/3 | NCT03367988 Background | Dec 2018 → Jan 2023 | drug dependence | University of South Florida | Unknown | No outcome recorded |
| Phase 2/3 | NCT02393664 Comparator | Mar 2015 → Oct 2016 | lung neoplasm | National Taiwan University Hospital | Unknown | No outcome recorded |
| Phase 2/3 | NCT01279499 Comparator | Apr 2010 → Jun 2011 | morbid obesity | University of Patras | Unknown | No outcome recorded |
| Phase 2/3 | NCT00762372 Comparator | Feb → Aug 2008 | — | Baxter Healthcare Corporation | Completed | No outcome recorded |
| Phase 322 trials | ||||||
| Phase 3 | NCT07299630 Background | Dec 2025 → May 2026 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT06624592 Comparator | Dec 2024 → Nov 2026 expected | delirium | Mayo Clinic | Recruiting | No outcome recorded |
| Phase 3 | NCT07289945 Comparator | Sep 2024 → Apr 2025 | cognitive disorder | Hopital Charles Nicolle | Completed | No outcome recorded |
| Phase 3 | NCT06271174 Background | Jun 2024 → Jun 2026 | — | Nantes University Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT05444751 Comparator | Mar 2022 → Sep 2026 expected | lumbar disk disease, radiculopathy | Hospital for Special Surgery, New York | Enrolling by invitation | No outcome recorded |
| Phase 3 | NCT04144933 Comparator | May 2021 → Jul 2024 | paralytic ileus | University of Saskatchewan | Unknown | No outcome recorded |
| Phase 3 | NCT04513808 Comparator | Aug 2020 → Dec 2025 overdue | esophageal cancer | The Cleveland Clinic | Recruiting | No outcome recorded |
| Phase 3 | NCT04316013 Comparator | Jul 2020 → Feb 2025 | colon carcinoma, non-small cell lung carcinoma, rectal carcinoma | Peter MacCallum Cancer Centre, Australia | Terminated | No outcome recorded |
| Phase 3 | NCT04081545 Background | Dec 2019 → Mar 2023 | substance-related disorder | Christine Oryhan | Completed | No outcome recorded |
| Phase 3 | NCT03825198 Comparator | Aug 2019 → Dec 2023 | neuropathy, painful, peripheral nerve lesion | Dr M. B. Breebaart | Unknown | No outcome recorded |
| Phase 3 | NCT02987985 Background | Oct 2017 → Sep 2019 | obstructive sleep apnea syndrome, respiratory underresponsiveness to hypoxia and hypercapnia | University of Saskatchewan | Completed | No outcome recorded |
| Phase 3 | NCT02559102 Comparator | Jul 2015 → Jul 2020 | hernia, double inguinal, neurodevelopmental disorder | KK Women's and Children's Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02322502 Comparator | Feb 2015 → Feb 2016 | — | RWTH Aachen University | Completed | No outcome recorded |
| Phase 3 | NCT02455440 Comparator | Mar 2014 → Jul 2015 | brain aneurysm | George Papanicolaou Hospital | Completed | No outcome recorded |
| Phase 3 | NCT01285271 Comparator | May → Sep 2011 | coronary artery disorder | RWTH Aachen University | Completed | No outcome recorded |
| Phase 3 | NCT01294163 Comparator | Apr 2011 → Apr 2014 | coronary artery disorder, drug allergy | Air Liquide | Completed | No outcome recorded |
| Phase 3 | NCT01219881 Comparator | Sep 2010 → Oct 2012 | — | Ohio State University | Completed | No outcome recorded |
| Phase 3 | NCT01120405 Comparator | May 2010 → Jul 2012 | coronary artery disorder | Air Liquide | Completed | No outcome recorded |
| Phase 3 | NCT00531349 Comparator | Nov 2007 | cancer | The Cleveland Clinic | Withdrawn | No outcome recorded |
| Phase 3 | NCT00418457 Comparator | Jan 2007 → Feb 2018 | breast neoplasm | The Cleveland Clinic | Completed | No outcome recorded |
| Phase 3 | NCT00984633 Background | Jun → Dec 2003 | — | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 3 | NCT00988520 Background | May → Sep 2003 | — | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 4121 trials | ||||||
| Phase 4 | NCT07663877 Comparator | Jun 2026 → Jun 2028 expected | — | Chung-Ang University Gwangmyeong Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06876870 Comparator | Oct 2025 → Dec 2026 expected | — | Uppsala University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06457958 Comparator | Jun → Aug 2025 | cholecystitis | Kocaeli City Hospital | Withdrawn | No outcome recorded |
| Phase 4 | NCT06330038 Comparator | Aug 2024 → Dec 2028 expected | non-small cell lung carcinoma | Samsung Medical Center | Recruiting | No outcome recorded |
| Phase 4 | NCT06378645 Comparator | Feb 2024 → Dec 2026 expected | — | Etienne Xavier Keller | Recruiting | No outcome recorded |
| Show all 121 trials opens the full record — a long page | ||||||
| Phase not applicable178 trials | ||||||
| — | NCT07665463 Background | Jul → Dec 2026 expected | — | Jagiellonian University | Not yet recruiting | No outcome recorded |
| — | NCT07680400 Background | Jul → Aug 2026 overdue | — | Bezmialem Vakif University | Not yet recruiting | No outcome recorded |
| — | NCT07653490 Background | Jun 2026 → May 2027 expected | — | Taksim Egitim ve Arastirma Hastanesi | Recruiting | No outcome recorded |
| — | NCT07485517 Comparator | Jun → Dec 2026 expected | — | Menoufia University | Not yet recruiting | No outcome recorded |
| — | NCT07558226 Comparator | May 2026 → Nov 2027 expected | — | Fundacio Puigvert | Recruiting | No outcome recorded |
| Show all 178 trials opens the full record — a long page | ||||||
Evidence & citations 29 cited values
Every value below carries the sentence it was read from. 586 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Sevoflurane | “The general anesthesia group will receive sevoflurane (intervention drug) for induction and maintenance of general anesthesia, dose up to 8% inspired for duration of procedure...” NCT00756600 ↗581“In the inhalation anesthesia group, anesthesia is induced by pentothal sodium 4-6mg/kg and remifentanil 1 μg/kg, and then maintained with end-tidal sevoflurane concentration of...” NCT02813044 ↗ “Prospective clinical monocentric study in ICU with sedated ventilated obese patients with sevoflurane during 48 h with the AnaConda® system, establishing pharmacokinetic model...” NCT02042612 ↗ “This is a prospective, randomized controlled clinical trial evaluating the effects of ultra-low fresh gas flow (0.5 L/min) versus normal fresh gas flow (2.0 L/min) sevoflurane...” NCT07313969 ↗ “General anesthesia with intraoperative remifentanil infusion, sevoflurane maintenance, non-opioid co-analgesics, procedure-specific regional analgesia, and standardized...” NCT07665463 ↗ “The aim of this study was to compare the recovery of 2 Bispectral index (BIS)-guided anesthesia protocols combining sevoflurane-sufentanil (SS) or propofol-remifentanil (PR)...” PMID 23774117 ↗ Jan 2014 “Anesthesia maintenance: After endotracheal intubation, half of the patients will be randomized into Sevoflurane Group. The gas flow rate of Desflurane group is 2 L/min, 50％O2...” NCT02909413 ↗ “Anesthesia induction was performed using propofol and remifentanil, followed by maintenance with sevoflurane to ensure adequate anesthetic depth and hemodynamic stability...” NCT07097220 ↗ “Anesthesia will be maintained with Sevoflurane, Magnesium, Lidocaine, Ketamine, Decadron, Ondansetron, and Ketorolac at a concentration range/dose(s) based on the clinical need...” NCT03367988 ↗ “anesthesia was maintained by sevoflurane and remifentanil (0.1 μg kg-1 min-1), and primary anaesthetic namely sevoflurane was titrated to maintain intraoperative BIS values...” NCT01304953 ↗ “Aim of this trial is to compare propofol-based anaesthesia vs. sevoflurane-based anaesthesia induction in patients with cervical myelopathy receiving oral or nasal fiberoptic...” NCT01052337 ↗ “Balanced anesthesia induced with sufentanil,etomidate,cisatracurium and midazolam and maintained with cisatracurium and remifentanil target controlled infusion and sevoflurane...” NCT03129009 ↗ “Pediatric patients who are planned to undergo an MRI scan with generalized anesthesia will be randomized to either IV anesthesia with propofol or inhalation anesthesia with sevoflurane.” NCT06876870 ↗ “Maintenance of general anesthesia: propofol infusion (50-150 μg.kg.min-1); ketamine infusion (up to 50 mg total); and inhaled anesthetic agent (isoflurane or sevoflurane) up to 0.5 MAC.” NCT05444751 ↗ “In Group VA (volatile/inhalation anaesthesia group), maintenance anaesthesia will be administered with sevoflurane and remifentanil infusion following intravenous induction.” NCT07325669 ↗ “General anesthesia will be induced with fentanyl 1,5 mcg/kg, propofol 2 mg/kg, rocuronium 0,6 mg/kg; after intubation anesthesia will be mantained with sevoflurane (MAC 1).” NCT04294537 ↗ “The intervention was maintenance of anesthesia with sevoflurane (n = 231) or isoflurane (n = 233) administered at a dose of 0.5-2.0 MAC throughout the entire operation.” PMID 27465213 ↗ Jul 2016 “The GAS group will receive one or more volatile anesthetics (sevoflurane, desflurane, or isoflurane) for induction and maintenance of anesthesia during the surgery.” NCT06330038 ↗ “Propofol infusion according to body weight will be compared with sevoflurane acording to MAC % to see the lactate level and hemodynamic parameters of CABG patients” NCT05004545 ↗ “Anesthetic agents, including propofol, fentanyl, rocuronium, and sevoflurane, were used as part of standard anesthetic management during the procedure.” NCT07370779 ↗ “General anesthesia induction will be performed with fentanyl 1-2 μg/kg, propofol 2-3 mg/kg, and rocuronium 0.6 mg/kg and maintained with sevoflurane.” NCT06584695 ↗ “Standardized general anaesthesia with fentanyl 2 mcg/kg ABW at induction, propofol 1.5 mg/kg, rocuronium 0.6 mg/kg, sevoflurane 1 MAC for maintenance” NCT07299630 ↗ “patients for whom general anesthesia will be performed with sevoflurane and patients for whom general anesthesia will be performed with desflurane” NCT06759623 ↗ “The patients in the Sevoflurane Group (SG) will be induced with remifentanil TCI at target dose of 8.0 ηg.ml-1 and etomidate 0.5 mg.kg-1 in bolus.” NCT00792779 ↗ “if inhalational maintenance of anesthesia is used it will be achieved with sevoflurane 1% to 2% or desflurane 3% to 6% end-tidal concentration” NCT03263117 ↗ “General anesthesia will be maintained with inhalation (sevoflurane) and muscle relaxants will be administered when considered necessary.” NCT03245346 ↗ “all patients will receive inhalational anesthetic induction with 8% sevoflurane in 100% oxygen at a flow rate of 10 L/min via face mask” NCT07680400 ↗ “Experimental group: will receive sedation with sevoflurane with an infusion rate to maintain MAC of 0.7 and fentanyl 1mcg /kg/hour.” NCT04998253 ↗ “Inhalational isoflurane or sevoflurane will be administered as a general anesthetic at the induction of the surgical procedure.” NCT05639686 ↗ “Anesthesia is maintained by 1-1.5% sevoflurane, 0.5 µg/kg/h fentanyl, 0.05 mg/kg/h nimbex, 60% nitrous oxide and 40% oxygen.” NCT02534012 ↗ “As soon as mechanical ventilation started, sevoflurane was opened at a concentration of 2-3% with a MAK value of 1.1-1.3.” NCT04310748 ↗ “The inhalation group will be maintained with inhaled sevoflurane and a continuous intravenous infusion of remifentanil.” NCT07601256 ↗ “Patients will be randomized to Sevoflurane or Desflurane as the single volatile anesthetics for general anesthesia.” NCT04395248 ↗ “an inhalatory hypnotic, Sevoflurane, as anesthetic co-induction by these 2 agents is generally used in pediatrics.” NCT06271174 ↗ “combined general anesthesia (infusion of Ketamine, Lignocaine and Dexmedetomidine and inhalation of Sevoflurane)” NCT06390046 ↗ “Hemodynamic Stability During Carotid Endarterectomy.Comparison of LENOXe™ (Xenon 100% v/v) Versus Sevoflurane” NCT00937807 ↗ “The administered drugs, as outlined in the arms section, are midazolam, fentanyl, propofol, and sevoflurane.” NCT02058511 ↗ “Sevoflurane and propofol are widely used for the maintenance of general anesthesia during bariatric surgery.” NCT03946657 ↗ “In the volatile anesthetic group, sevoflurane will be administrated during the organ procurement procedure.” NCT07166991 ↗ “Anesthesia will be maintained by sevoflurane and remifentanil infusion in the balanced anesthesia group.” NCT05951842 ↗ “standard care which includes ketorolac, bupivacaine, fentanyl, ondansetron, dexamethasone, sevoflurane” NCT01868425 ↗ “General anesthesia is performed with propofol induction and propofol and/or sevoflurane maintenance.” NCT03012945 ↗ “Participants will receive a dexmedetomidine infusion in addition to low dose sevoflurane anesthesia.” NCT05369949 ↗ “Continuous infusion of remifentanil at 0.05 ~ 2 mcg/kg/min with sevoflurane concentration of 1 MAC” NCT01634594 ↗ “Maintenance of general anesthesia with volatile agent (sevoflurane, desflurane, or isoflurane)” NCT03034096 ↗ “Then maintained using Sevoflurane based anesthesia aiming to maintain Bispectral index 40-60..” NCT02768376 ↗ “During the operation, sevoflurane (MAC1.0 - 1.4) was used to maintain the depth of anesthesia” NCT05577962 ↗ “Maintenance with sevoflurane 1-3%, fentanyl (1-2 µg kg-1), nitrous oxide 70% and oxygen 30%.” NCT02355678 ↗ “preconditioning with sevoflurane is a protective factor against ischemia-reperfusion injury” PMID 27549313 ↗ Aug 2016 “maintenance anesthetic consisting of remifentanil and sevoflurane (Sevoflurane Group)” PMID 24500661 ↗ Feb 2014 “All patients will undergo inhalational induction with nitrous oxide and sevoflurane.” NCT03467750 ↗ “Patients were randomized to maintenance of anesthesia with sevoflurane or propofol.” PMID 23136158 ↗ Nov 2012 “sevoflurane in 1 MAC (Minimal Alveolar Concentration) - anesthesia maintenance” NCT02840526 ↗ “supplemental sedation with the remedial drug sevoflurane or propofol is used” NCT06775366 ↗ “Pharmacologic preconditionig will be attained by sevoflurane anesthesia” NCT03097692 ↗ “Anesthesia maintenance - Sevoflurane/rocuronium, fentanyl 0.5-1mcg/kg” NCT03448068 ↗ “Sevoflurane or desflurane for induction and maintenance of anesthesia” NCT04503148 ↗ “To maintain a target of sevoflurane inhalation concentration 0.8 MAC.” NCT04292561 ↗ “Anesthesia is maintained with 1.0-2.5% sevoflurane and remifentanil.” NCT04063046 ↗ “a potent inhalation agent (sevoflurane 1.5%-2.5%) during procedures” NCT01566838 ↗ “General anesthesia, usually with sevoflurane, and opioid analgesia” NCT00418457 ↗ “Drug: High dose propofol, fentanyl and sevoflurane Deep Anesthesia” NCT05380778 ↗ “sevoflurane general anesthesia and postoperative opioid analgesia” NCT00684229 ↗ “Investigation of the effect of Sevoflurane on muscle relaxation” NCT07080528 ↗ “volatile induction and maintenance anesthesia with sevoflurane” NCT03094533 ↗ “Group "INH/100" was induced with 8% sevoflurane in 100% oxygen” PMID 31694576 ↗ Nov 2019 “Dexmedetomidine 0.5 ug/kg + Propofol + Sevoflurane+ Vecuronium” NCT01584570 ↗ “Sevoflurane will be administered as an inhalation anesthetic.” NCT07534956 ↗ “or sevoflurane with 1 microgram/kilogram (mcg/kg) of fentanyl” NCT03408340 ↗ “Using inhalational induction with sevoflurane as tolerated” NCT04614259 ↗ “Maintenance of anesthesia with sevoflurane, oxygen and air” NCT01511627 ↗ “Sevoflurane 0.5\~1.5MAC（minimum alveolar concentration）” NCT02727712 ↗ “Anesthesia was induced and maintained with sevoflurane” NCT02416063 ↗ “Inhalation Sedation by Administration of Sevoflurane” NCT04014218 ↗ “an end-tidal concentration of 2-3% sevoflurane” NCT07485517 ↗ “sevorane Quick fill (sevoflurane) : inhalation” NCT03772106 ↗ “Sevoflurane at a concentration of 2-2.5%” NCT03778723 ↗ “Sevoflurane 0.7-1.5 MAC in 40% oxygen” NCT04541732 ↗ “sevoflurane, propofol” NCT01866657 ↗ “0.5 MAC Sevoflurane” NCT02711917 ↗ “Sevoflurane group” NCT03311581 ↗ “* Sevoflurane” NCT04081545 ↗ “sevoflurane” NCT03094533 ↗ “sevoflurane” NCT02567929 ↗ “Sevoflurane” NCT04874545 ↗ |
| Known as | Fluoromethyl hexafluoroisopropyl ether | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03005860 ↗ |
| Known as | inhalation anesthesia | “inhalation anesthesia” NCT05926336 ↗ |
| Known as | Inhalational anesthetic | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03946657 ↗ |
| Known as | Kaiteli | “Anesthesia was maintained with sevoflurane (Inhalation Sevoflurane, Brand: Kaiteli” NCT07192549 ↗ |
| Known as | MR-6S4 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200694 ↗ |
| Known as | NSC-760367 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200694 ↗ |
| Known as | SEVO | “Microdialysis probes were implanted in three groups of 10 patients each receiving either sevoflurane (SEVO), propofol (PRO), or spinal (SA) anaesthesia (for induction and maintenance).” PMID 18029344 ↗ Nov 20071“While sevoflurane (SEVO) has been associated with potential renal risks” NCT06835010 ↗ |
| Known as | Sevocalm | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200694 ↗ |
| Known as | Sevoflo | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200694 ↗ |
| Known as | Sevofluorane | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07123870 ↗ |
| Known as | Sevoflurane (sevorane) | “Sevoflurane (sevorane)” NCT02267980 ↗ |
| Known as | Sevoflurane, Sevocris (Cristalia Lab, Sao Paulo, Brazil) | “Sevoflurane, Sevocris ® (Cristalia Lab, Sao Paulo, Brazil)” NCT02284204 ↗ |
| Known as | Sevoflurane/ Ultane 250mL/Bot | “Sevoflurane/ Ultane 250mL/Bot” NCT05606692 ↗ |
| Known as | Sevoflurano | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200694 ↗ |
| Known as | sevofran | “adjust the end-tidal sevoflurane (sevofran inhaler, Hana pharmacy, Korea) concentration maintaining the 40 \~ 50 BIS” NCT02609087 ↗ |
| Known as | Sevohale (previously known as sevocalm) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200694 ↗ |
| Known as | sevorane | “Administration of sevoflurane (SEVORANE) by inhalation until a maximal concentration of 4% of inspired gas.” NCT01006668 ↗6“inhalation introduction (Sevorane, 02,AIR (flow 2:2 l/min))” NCT02664142 ↗ “sevorane Quick fill (sevoflurane) : inhalation” NCT03772106 ↗ “Sevorane (sevoflurane, Abbott)” NCT00541918 ↗ “Propofol/sevorane” NCT07558226 ↗ |
| Known as | Sojourn | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200694 ↗ |
| Known as | Ultane | “1-3% sevoflurane (ULTANE®, AbbVie Inc., USA) in the Sevoflurane group.” NCT03263078 ↗1“Sevoflurane/Ultane” NCT05606692 ↗ |
| Action | Activate | “Potassium channel subfamily K member 18 opener” CHEMBL1200694 ↗4“Potassium channel subfamily K member 10 opener” CHEMBL1200694 ↗ “Potassium channel subfamily K member 3 opener” CHEMBL1200694 ↗ “Potassium channel subfamily K member 2 opener” CHEMBL1200694 ↗ “Potassium channel subfamily K member 9 opener” CHEMBL1200694 ↗ |
| Action | Inhibit | “The volatile anesthetics such as sevoflurane and desflurane are known to block the muscarinic receptor in different ways.” NCT02096224 ↗ |
| Modality | Other / unclassified | “Sevoflurane (a volatile-inhaled anesthetic)” NCT00337051 ↗ |
| Route | Inhaled | “combined sevoflurane and nitrous oxide inhalation” NCT00000262 ↗ |
| Target | KCNK10 | “Potassium channel subfamily K member 10 opener” CHEMBL1200694 ↗ |
| Target | KCNK18 | “Potassium channel subfamily K member 18 opener” CHEMBL1200694 ↗ |
| Target | KCNK2 | “Potassium channel subfamily K member 2 opener” CHEMBL1200694 ↗ |
| Target | KCNK3 | “Potassium channel subfamily K member 3 opener” CHEMBL1200694 ↗ |
| Target | KCNK9 | “Potassium channel subfamily K member 9 opener” CHEMBL1200694 ↗ |