drugset / Trial / NCT05019222

Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam

NCT05019222

Completed 72 enrolled Gangnam Severance Hospital
RandomizedParallel-groupTriple-blindOther

Summary

The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperative nausea/vomiting and malignant hyperthermia. However, it is still not enough to explain which is better between TIVA or inhalation anesthesia. In particular, there is no study to investigate overall postoperative functional recovery via QoR-15 in patients receiving TIVA with remimazolam. The hypothesis of the investigators study is that, in patients with cervical spine surgery, total intravenous anesthesia based on remimazolam can improve the the quality of recovery compared to inhalation anesthesia based on sevoflurane.

Timeline

Start
2021-09-26
Primary completion
2022-08-14
Completion
2022-08-14

Drugs

EvaluationDrugModalityDoseRoute
Comparator Remimazolam Small molecule Intravenous
Subject Sevoflurane Other / unclassified Inhaled
Background Propofol Small molecule
Comparator Remifentanil Small molecule

Indications