Remifentanil

also known as Ultiva · Remifentanyl · Remifentanil Hydrochloride · Remifentanil: Ultiva · Extubation U · Fada Remifentanilo · GI 87084B · GI 87084X · +11 more

Small molecule targets OPRM1 via activation

Developed for: delirium · osteoarthritis · substance-related disorder · cardiac rhythm disease · cardiac valvular defect · chronic pain syndrome · hypertensive disorder · hypotensive disorder
+22 more
· respiratory distress syndrome in premature infants · respiratory failure · acquired aneurysmal subarachnoid hemorrhage · acute kidney injury · acute respiratory failure · crush syndrome · hyperglycemia · intracerebral hemorrhage · myocardial ischemia · neuropathy, painful · postherpetic neuralgia · thyroid gland disorder · traumatic brain injury · urolithiasis · leiomyoma · lung disorder · nose, anomalous shape of · outlet dysfunction constipation · pain agnosia · potassium deficiency · pulmonary immaturity · subacute delirium
Investigated by: Ajou University School of Medicine · Yonsei University · Seoul National University Hospital · GlaxoSmithKline · Changhai Hospital · Medical University of Vienna
+212 more
· Shanghai Zhongshan Hospital · Hopital Foch · Ruijin Hospital · Shanghai Pulmonary Hospital, Shanghai, China · Assistance Publique - Hôpitaux de Paris · Capital Medical University · Medical University of Silesia · Nîmes University Hospital · Oslo University Hospital · Region Skane · Severance Hospital · Tri-Service General Hospital (TSGH) · University Hospital, Clermont-Ferrand · Ankara City Hospital Bilkent · Baylor College of Medicine · Beijing Tiantan Hospital · Boston Children's Hospital · Brasilia University Hospital · CMC Ambroise Paré · Catholic University of the Sacred Heart · Children's Hospital of Philadelphia · Gangnam Severance Hospital · Hallym University Medical Center · Jeju National University School of Medicine · KK Women's and Children's Hospital · Kaohsiung Medical University Chung-Ho Memorial Hospital · Murdoch Childrens Research Institute · Region Örebro County · Royal Children's Hospital · Southeast University, China · Sydney Children's Hospitals Network · The Cleveland Clinic · The Hospital for Sick Children · University Hospital, Geneva · University Hospital, Ghent · University Hospital, Toulouse · University Medical Center Groningen · University of California, San Francisco · Yangzhou University · AZ Sint-Jan AV · Aalborg University Hospital · Alder Hey Children's NHS Foundation Trust · Anders Troelsen · Arthritis Research UK · Azienda Ospedaliera San Gerardo di Monza · Basque Health Service · Beth Israel Deaconess Medical Center · Bezmialem Vakif University · C. R. Bard · Central Hospital, Nancy, France · Central South University · Centre Hospitalier Sud Francilien · Centre Hospitalier Universitaire Vaudois · Centre Hospitalier Universitaire de Besancon · Charles University, Czech Republic · Children's Hospital Medical Center, Cincinnati · Chosun University Hospital · Chun Pan · Ciusss de L'Est de l'Île de Montréal · Columbia University · Cukurova University · Department of Biostatistics, Southern Medical University · Diskapi Teaching and Research Hospital · Diskapi Yildirim Beyazit Education and Research Hospital · Dr. Erfan and Bagedo General Hospital · Duke University · Erasme University Hospital · Fatih Sultan Mehmet Training and Research Hospital · Federal University of Minas Gerais · Fifth Affiliated Hospital, Sun Yat-Sen University · First Affiliated Hospital of Harbin Medical University · First Affiliated Hospital of Kunming Medical University · First Affiliated Hospital of Xinjiang Medical University · Flinders Medical Centre · all 218 on the full record

Regulatory milestones approvals, filings & regulatory actions · 4 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Label expansions (3)	US (FDA)	ULTIVA	—	1999-10-15 – 2004-03-08	fda.gov ↗
Approved	US (FDA)	ULTIVA	—	1996-07-12	fda.gov ↗

Trials 222 · started per year

today

US approved 1996

199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 02 trials
Phase 0	NCT06312657	Mar 2023 → Mar 2025	substance-related disorder	University of Kentucky	Terminated	No outcome recorded
Phase 0	NCT02898792	Sep 2016 → May 2018	sleep apnea syndrome	Washington University School of Medicine	Completed	No outcome recorded
Phase 15 trials
Phase 1	NCT07603596	May 2026 → Apr 2028 expected	delirium, digestive system neoplasm	Qianfoshan Hospital	Not yet recruiting	No outcome recorded
Phase 1	NCT04670471	Apr 2021 → Jan 2022	—	Paion UK Ltd.	Completed	No outcome recorded
Phase 1	NCT04301895	Apr → Sep 2019	acute opioid poisoning, respiratory underresponsiveness to hypoxia and hypercapnia	University of California, San Francisco	Completed	No outcome recorded
Phase 1	NCT02473354	Apr 2015 → Apr 2018	respiratory underresponsiveness to hypoxia and hypercapnia	Duke University	Completed	No outcome recorded
Phase 1	NCT02602002	Apr → Jun 2008	—	GlaxoSmithKline	Completed	No outcome recorded
Phase 1/24 trials
Phase 1/2	NCT03928366	Jun 2017 → Jan 2019	codeine toxicity	Parc de Salut Mar	Completed	No outcome recorded
Phase 1/2	NCT01477892	Dec 2011 → Apr 2012	—	Seoul National University Hospital	Completed	No outcome recorded
Phase 1/2	NCT00213239	Sep 2005 → Sep 2007	hematologic disorder, neoplasm	The Hospital for Sick Children	Completed	No outcome recorded
Phase 1/2	NCT00730054	Feb → May 2005	—	Oslo University Hospital	Completed	No outcome recorded
Phase 26 trials
Phase 2	NCT04204967	Feb 2021 → Apr 2024	respiratory failure	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Completed	No outcome recorded
Phase 2	NCT03443518	Feb → Nov 2018	—	Dr. Erfan and Bagedo General Hospital	Completed	No outcome recorded
Phase 2	NCT02432677	Jul 2014 → Dec 2015	—	Hospital de Clinicas de Porto Alegre	Unknown	No outcome recorded
Phase 2	NCT00522587	Apr 2008 → Jul 2009	—	University Hospital, Ghent	Completed	No outcome recorded
Phase 2	NCT00693160	Dec 2007 → Oct 2010	—	Wake Forest University	Terminated	No outcome recorded
Phase 2	NCT00315536	May 2006 → Apr 2009	—	University Hospital, Ghent	Completed	No outcome recorded
Phase 2/31 trial
Phase 2/3	NCT05391555	Oct 2022 → Jun 2023	abnormal pupillary function, poisoning, respiratory underresponsiveness to hypoxia and hypercapnia	University of California, San Francisco	Completed	No outcome recorded
Phase 320 trials
Phase 3	NCT05641909	Aug 2021 → Dec 2022	—	Southeast University, China	Unknown	No outcome recorded
Phase 3	NCT05003570	Jun 2021 → Dec 2022	—	Southeast University, China	Unknown	No outcome recorded
Phase 3	NCT03960801	Oct 2019 → Apr 2021	—	Nantes University Hospital	Completed	No outcome recorded
Phase 3	NCT03618082	Jun 2019 → May 2022	—	University Hospital, Clermont-Ferrand	Unknown	No outcome recorded
Phase 3	NCT03089905	Aug 2017 → Mar 2026 overdue	poisoning	Murdoch Childrens Research Institute	Active not recruiting	No outcome recorded
Phase 3	NCT03065309	Feb 2017	hypotensive disorder	Brasilia University Hospital	Completed	No outcome recorded
Phase 3	NCT02597699	Dec 2015 → Mar 2019	—	University Hospital, Montpellier	Completed	No outcome recorded
Phase 3	NCT02481791	Jul 2015 → Dec 2019	heart disorder	Alder Hey Children's NHS Foundation Trust	Unknown	No outcome recorded
Phase 3	NCT02033629	May 2014 → May 2019	cardiac valvular defect	Imam Abdulrahman Bin Faisal University	Completed	No outcome recorded
Phase 3	NCT01998165	Nov 2013 → Nov 2014	—	Janssen Pharmaceutical K.K.	Completed	No outcome recorded
Phase 3	NCT01735669	Jul 2012 → Apr 2013	neonatal compartment syndrome, pregnancy disorder	Hospital de Cruces	Completed	No outcome recorded
Phase 3	NCT01102101	Aug 2010 → Mar 2011	postherpetic neuralgia	Medical University of Vienna	Unknown	No outcome recorded
Phase 3	NCT01048398	Jun 2010 → Apr 2011	pregnancy disorder	Basque Health Service	Completed	No outcome recorded
Phase 3	NCT02093143	Jun 2009 → Feb 2013	upper aerodigestive tract neoplasm	Centre Hospitalier Universitaire de Besancon	Completed	No outcome recorded
Phase 3	NCT00741351	Dec 2007 → Mar 2009	—	Azienda Ospedaliera San Gerardo di Monza	Completed	No outcome recorded
Phase 3	NCT00436345	Nov 2007 → Aug 2008	—	GlaxoSmithKline	Terminated	No outcome recorded
Phase 3	NCT00474071	Mar 2007 → Apr 2008	—	University of British Columbia	Completed	No outcome recorded
Phase 3	NCT00419601	Nov 2006 → Apr 2010	—	University of Cologne	Completed	No outcome recorded
Phase 3	NCT00405522	Nov 2006 → Jun 2007	—	The Hospital for Sick Children	Completed	No outcome recorded
Phase 3	NCT00389883	Nov 2006 → Jan 2010	supratentorial cancer	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded

Phase 482 trials
Phase 4	NCT07334132	Apr 2026 → Dec 2029 expected	osteoarthritis	Region Örebro County	Not yet recruiting	No outcome recorded
Phase 4	NCT06564857	Nov 2025 → Apr 2027 expected	—	Nordsjaellands Hospital	Recruiting	No outcome recorded
Phase 4	NCT07105839	Aug 2025 → Jan 2026 overdue	obesity disorder	Siirt Training and Research Hospital	Not yet recruiting	No outcome recorded
Phase 4	NCT01003028	Nov 2024 → Dec 2025 overdue	—	Seoul National University Hospital	Not yet recruiting	No outcome recorded
Phase 4	NCT06454292	Jun 2024 → Dec 2025	—	Chun Pan	Unknown	No outcome recorded
Phase 4	NCT06331663	Apr → Jun 2024	—	Kaohsiung Medical University Chung-Ho Memorial Hospital	Unknown	No outcome recorded
Phase 4	NCT05876039	May 2023 → Aug 2024	—	Tri-Service General Hospital (TSGH)	Completed	No outcome recorded
Phase 4	NCT05825560	May 2023 → Jun 2026	—	Nîmes University Hospital	Completed	No outcome recorded
Phase 4	NCT05125328	Apr → Jun 2023	—	Kaohsiung Medical University Chung-Ho Memorial Hospital	Completed	No outcome recorded
Phase 4	NCT05706844	Mar 2023 → Apr 2025	osteoarthritis, hip, osteoarthritis, knee	Anders Troelsen	Completed	No outcome recorded
Phase 4	NCT04073173	Nov 2020 → Oct 2022	respiratory distress syndrome in premature infants	Virgilio Paolo Carnielli	Unknown	No outcome recorded
Phase 4	NCT03994146	Jan 2020 → Aug 2023	—	University Hospital, Akershus	Terminated	No outcome recorded
Phase 4	NCT05014711	Jan 2020 → Dec 2021	—	Capital Medical University	Unknown	No outcome recorded
Phase 4	NCT04117009	Nov 2019 → Jun 2020	diastolic heart failure	Yeditepe University	Unknown	No outcome recorded
Phase 4	NCT04026074	Jul → Oct 2019	arthropathy	Medical University of Graz	Completed	No outcome recorded
Phase 4	NCT03783676	Feb → Jun 2019	—	University of Vermont Medical Center	Unknown	No outcome recorded
Phase 4	NCT03901716	Jan → Mar 2019	—	Guangzhou Institute of Respiratory Disease	Completed	No outcome recorded
Phase 4	NCT03812003	Jan → Dec 2019	substance-related disorder	Tri-Service General Hospital (TSGH)	Completed	No outcome recorded
Phase 4	NCT03143972	Jun 2017 → Feb 2018	—	University Medical Center Groningen	Completed	No outcome recorded
Phase 4	NCT02655380	Jun 2017 → Apr 2018	—	Ajou University School of Medicine	Completed	No outcome recorded
Phase 4	NCT02733835	Dec 2016 → Dec 2017	—	KK Women's and Children's Hospital	Unknown	No outcome recorded
Phase 4	NCT02602743	Aug 2016 → Jan 2017	—	Cukurova University	Completed	No outcome recorded
Phase 4	NCT02999126	Aug 2016 → Dec 2020	—	Hospital Italiano de Buenos Aires	Unknown	No outcome recorded
Phase 4	NCT02454868	Jul 2016	—	Brasilia University Hospital	Completed	No outcome recorded
Phase 4	NCT02799589	Jul 2016 → Aug 2017	—	Mofya Diallo	Withdrawn	No outcome recorded
Phase 4	NCT02809378	Jun 2016 → Apr 2017	—	Ajou University School of Medicine	Completed	No outcome recorded
Phase 4	NCT02717780	Feb 2016 → Jun 2018	obstructive sleep apnea syndrome	Centre Hospitalier Universitaire Vaudois	Completed	No outcome recorded
Phase 4	NCT02349152	Jan → Dec 2016	heart disorder, hyperglycemia	Kathirvel Subramaniam	Completed	No outcome recorded
Phase 4	NCT02635802	Dec 2015 → Jun 2016	—	The First Affiliated Hospital of Zhengzhou University	Unknown	No outcome recorded
Phase 4	NCT02566733	Oct 2015 → Jun 2016	—	Seoul National University Hospital	Completed	No outcome recorded
Phase 4	NCT02353182	May 2015 → Sep 2016	—	Murdoch Childrens Research Institute	Completed	No outcome recorded
Phase 4	NCT02486328	May → Jun 2015	cognitive disorder, digestive system disorder	Ufuk University	Completed	No outcome recorded
Phase 4	NCT02382354	Mar → Sep 2015	—	Ajou University School of Medicine	Completed	No outcome recorded
Phase 4	NCT02334046	Feb → Nov 2015	substance abuse	Ajou University School of Medicine	Completed	No outcome recorded
Phase 4	NCT02593942	Jan → Sep 2015	supratentorial cancer	Yeditepe University Hospital	Completed	No outcome recorded
Phase 4	NCT02208778	Dec 2014 → Jun 2016	chronic pain syndrome, osteoarthritis	University of Nottingham	Completed	No outcome recorded
Phase 4	NCT02379715	Dec 2014 → May 2015	—	Ajou University School of Medicine	Completed	No outcome recorded
Phase 4	NCT02528825	Nov 2014 → Aug 2015	—	Ajou University School of Medicine	Completed	No outcome recorded
Phase 4	NCT02206022	Aug 2014 → Dec 2017	—	University Hospital, Toulouse	Completed	No outcome recorded
Phase 4	NCT02078583	Jul 2014 → Jun 2015	delirium	Peking University People's Hospital	Unknown	No outcome recorded
Phase 4	NCT02104297	Apr → Jun 2014	—	Diskapi Yildirim Beyazit Education and Research Hospital	Unknown	No outcome recorded
Phase 4	NCT03132519	Oct 2013 → Nov 2015	hypertensive disorder	Fundacion Clinica Valle del Lili	Completed	No outcome recorded
Phase 4	NCT01931683	Oct 2013 → Feb 2014	substance abuse	Ajou University School of Medicine	Completed	No outcome recorded
Phase 4	NCT01872754	Jul 2013 → Apr 2017	—	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded
Phase 4	NCT01910285	Jun 2013 → Sep 2015	—	University Hospital, Toulouse	Completed	No outcome recorded
Phase 4	NCT01930747	Apr 2013 → Dec 2015	—	AZ Sint-Jan AV	Completed	No outcome recorded
Phase 4	NCT02884310	Jan 2013 → Dec 2014	local anesthetic poisoning	Erasme University Hospital	Completed	No outcome recorded
Phase 4	NCT01761149	Dec 2012 → Mar 2013	nodular goiter	Central South University	Unknown	No outcome recorded
Phase 4	NCT01693185	Dec 2012 → Feb 2013	—	Konkuk University Medical Center	Completed	No outcome recorded
Phase 4	NCT01702389	Oct → Dec 2012	—	Oslo University Hospital	Completed	No outcome recorded
Phase 4	NCT01998217	Sep 2012 → Dec 2013	pancreas disorder	Changhai Hospital	Completed	No outcome recorded
Phase 4	NCT01634594	Jun 2012 → Feb 2013	autosomal dominant prognathism	Yonsei University	Completed	No outcome recorded
Phase 4	NCT01833819	Jun 2012 → Apr 2013	cholecystitis	Bezmialem Vakif University	Completed	No outcome recorded
Phase 4	NCT01628562	Jun 2012 → Sep 2014	cardiac rhythm disease, hypertensive disorder, myocardial ischemia	Diskapi Teaching and Research Hospital	Completed	No outcome recorded
Phase 4	NCT01974648	May 2012 → Jun 2013	—	Hospital General Universitario Gregorio Marañon	Completed	No outcome recorded
Phase 4	NCT02664922	May 2012 → Sep 2013	heart disorder	University of California, Los Angeles	Terminated	No outcome recorded
Phase 4	NCT01419405	Dec 2011 → Mar 2012	—	Oslo University Hospital	Completed	No outcome recorded
Phase 4	NCT01901575	Jul 2011 → Apr 2013	ventricular tachycardia	NYU Langone Health	Completed	No outcome recorded
Phase 4	NCT01259648	Mar 2011 → May 2014	cardiac rhythm disease	Nîmes University Hospital	Completed	No outcome recorded
Phase 4	NCT01191645	Oct → Nov 2010	dyskinesia of esophagus	Region Örebro County	Completed	No outcome recorded
Phase 4	NCT01139671	Jun 2010 → Jul 2011	—	University Hospital, Clermont-Ferrand	Completed	No outcome recorded
Phase 4	NCT01714388	May 2010 → Feb 2015	—	Medical University of Gdansk	Completed	No outcome recorded
Phase 4	NCT01052324	Mar → Nov 2010	cervical disk degenerative disorder, spinal stenosis	Yonsei University	Completed	No outcome recorded
Phase 4	NCT01291849	Mar → May 2010	—	Yonsei University	Completed	No outcome recorded
Phase 4	NCT01452880	Jan → Jul 2010	urolithiasis	University of Roma La Sapienza	Completed	No outcome recorded
Phase 4	NCT01025245	Nov 2009 → Jan 2010	—	Yonsei University	Completed	No outcome recorded
Phase 4	NCT01015482	Nov 2009 → Mar 2010	—	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT01627873	Aug 2009 → Jul 2011	—	Catholic University of the Sacred Heart	Completed	No outcome recorded
Phase 4	NCT00886106	Jun → Dec 2009	—	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT01229527	Apr 2009 → Dec 2010	—	Ospedale San Raffaele	Completed	No outcome recorded
Phase 4	NCT00811837	Jan → Jul 2009	—	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT00789386	Nov 2008 → Oct 2009	—	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT00778505	Oct 2008 → Dec 2012	—	Hopital Foch	Terminated	No outcome recorded
Phase 4	NCT00772616	Sep 2008 → Jan 2010	—	Hopital Foch	Completed	No outcome recorded
Phase 4	NCT00710086	Jul 2008 → Sep 2009	—	Nanjing Medical University	Completed	No outcome recorded
Phase 4	NCT00665119	Apr → Oct 2008	respiratory failure	Fondazione Poliambulanza Istituto Ospedaliero	Completed	No outcome recorded
Phase 4	NCT00611195	Jan 2008 → Oct 2012	respiratory tract infectious disorder	Thomas Erb	Completed	No outcome recorded
Phase 4	NCT00421720	Jan 2007 → ?	—	GlaxoSmithKline	Terminated	No outcome recorded
Phase 4	NCT00349245	Jun 2006 → Aug 2007	—	The University of Texas Health Science Center, Houston	Completed	No outcome recorded
Phase 4	NCT00326859	Aug 2005 → Sep 2006	—	Montreal Burn Centre	Terminated	No outcome recorded
Phase 4	NCT00158873	Sep 2004 → ?	—	GlaxoSmithKline	Completed	No outcome recorded
Phase 4	NCT00391105	Apr 2004 → Nov 2005	respiratory distress syndrome in premature infants	Federal University of Minas Gerais	Completed	No outcome recorded

Phase not applicable102 trials
—	NCT06727435	Aug 2026 → Apr 2028 expected	—	Beijing Tiantan Hospital	Not yet recruiting	No outcome recorded
—	NCT07695220	Jul 2026 → Oct 2028 expected	intracerebral hemorrhage	The Third Affiliated Hospital of Southern Medical University	Not yet recruiting	No outcome recorded
—	NCT07660861	Jun 2026 → Jun 2027 expected	intracranial berry aneurysm, intracranial hypertension	Fatih Sultan Mehmet Training and Research Hospital	Not yet recruiting	No outcome recorded
—	NCT07462949	Mar → Apr 2026	—	Guangzhou General Hospital of Guangzhou Military Command	Completed	No outcome recorded
—	NCT07640243	Feb → May 2026 overdue	cancer, cholangitis	Ankara City Hospital Bilkent	Recruiting	No outcome recorded
—	NCT07568405	Jan → Jun 2026 overdue	—	Université Libre de Bruxelles	Enrolling by invitation	No outcome recorded
—	NCT07328958	Jan → Dec 2026 expected	—	Sixth Affiliated Hospital, Sun Yat-sen University	Recruiting	No outcome recorded
—	NCT07325669	Jan 2026 → Jan 2027 expected	—	dilara gocmen	Not yet recruiting	No outcome recorded
—	NCT07310524	Sep → Nov 2025	—	Muhammad Rahman Efendi Nasution	Completed	No outcome recorded
—	NCT07092384	Jul → Nov 2025	—	Tongji Hospital	Completed	No outcome recorded
—	NCT07002801	Mar 2025 → Jun 2026 overdue	digestive system disorder	Harbin Medical University	Recruiting	No outcome recorded
—	NCT06658132	Oct 2024 → Feb 2025	Parkinson disease	RenJi Hospital	Completed	No outcome recorded
—	NCT06617039	Oct 2024 → Jul 2025 overdue	—	Northern Jiangsu People's Hospital	Active not recruiting	No outcome recorded
—	NCT06531837	Aug 2024 → Jan 2026 overdue	chronic pain syndrome	Beijing Tiantan Hospital	Not yet recruiting	No outcome recorded
—	NCT07094165	Jul 2024 → Mar 2025	acute kidney injury, crush syndrome, myopathy	Ankara City Hospital Bilkent	Completed	No outcome recorded
—	NCT06289829	Apr 2024 → Mar 2026	—	Yonsei University	Completed	No outcome recorded
—	NCT06237101	Mar 2024 → Aug 2026 overdue	—	University of Chile	Recruiting	No outcome recorded
—	NCT06162390	Nov 2023 → Mar 2024	thyroid gland disorder	Kyungpook National University Chilgok Hospital	Completed	No outcome recorded
—	NCT05936671	Jul 2023 → Jun 2025 overdue	—	Gangnam Severance Hospital	Recruiting	No outcome recorded
—	NCT05866315	May → Sep 2023	—	Wonkwang University Hospital	Completed	No outcome recorded
—	NCT05384665	May → Oct 2023	—	Centre Hospitalier Sud Francilien	Terminated	No outcome recorded
—	NCT05754762	Mar → Jul 2023	—	Yangzhou University	Unknown	No outcome recorded
—	NCT05279898	Feb 2023 → Jun 2024	delirium	Beth Israel Deaconess Medical Center	Completed	No outcome recorded
—	NCT07665645	Jan → Jun 2023	obesity disorder	Gaziantep City Hospital	Completed	No outcome recorded
—	NCT03763305	Jan → Dec 2023	—	Seoul National University Hospital	Withdrawn	No outcome recorded
—	NCT05551910	Jan 2023 → Jan 2025	—	The First Hospital of Jilin University	Unknown	No outcome recorded
—	NCT05548465	Sep 2022 → Oct 2023	—	West China Hospital	Completed	No outcome recorded
—	NCT05242081	Jul → Dec 2022	substance-related disorder	The First Affiliated Hospital with Nanjing Medical University	Unknown	No outcome recorded
—	NCT05217238	Dec 2021 → Mar 2022	—	Yangzhou University	Unknown	No outcome recorded
—	NCT05004519	Oct 2021 → Sep 2022	—	Matthieu Clanet	Completed	No outcome recorded
—	NCT06033729	Sep 2021 → Jul 2022	lung cancer	Scarlata, Simone, M.D.	Completed	No outcome recorded
—	NCT05076903	Sep 2021 → Nov 2022	—	Gangnam Severance Hospital	Completed	No outcome recorded
—	NCT03417206	Sep 2021 → Jan 2023	—	Medical University of Silesia	Unknown	No outcome recorded
—	NCT04940273	Jun → Dec 2021	acquired aneurysmal subarachnoid hemorrhage	Capital Medical University	Unknown	No outcome recorded
—	NCT04974060	Jun → Dec 2021	traumatic brain injury	Capital Medical University	Unknown	No outcome recorded
—	NCT04734418	Mar 2021 → Jan 2023	—	Shanghai Zhongshan Hospital	Unknown	No outcome recorded
—	NCT04553536	Nov 2020 → Jun 2023	poisoning	Second Hospital of Shanxi Medical University	Unknown	No outcome recorded
—	NCT04364945	Jun 2020 → May 2028 expected	toxic encephalopathy	Seoul National University Hospital	Active not recruiting	No outcome recorded
—	NCT04236323	Feb → Aug 2020	neuropathy, painful	Seoul National University Hospital	Completed	No outcome recorded
—	NCT03868111	Nov 2019 → Jan 2020	—	Kangbuk Samsung Hospital	Completed	No outcome recorded
—	NCT03983915	Jun → Nov 2019	—	Changhai Hospital	Unknown	No outcome recorded
—	NCT03983889	Jun → Nov 2019	—	Changhai Hospital	Unknown	No outcome recorded
—	NCT04492813	Dec 2018 → Jan 2021	obesity disorder	University Hospital, Clermont-Ferrand	Completed	No outcome recorded
—	NCT03517735	Dec 2018 → Mar 2019	—	CMC Ambroise Paré	Terminated	No outcome recorded
—	NCT03417180	Sep 2018 → Jul 2023	—	Medical University of Silesia	Unknown	No outcome recorded
—	NCT03622502	Aug 2018 → Mar 2019	—	Ajou University School of Medicine	Completed	No outcome recorded
—	NCT03817359	Aug → Dec 2018	—	Tri-Service General Hospital (TSGH)	Completed	No outcome recorded
—	NCT03540875	Jul 2018 → Feb 2019	—	CMC Ambroise Paré	Terminated	No outcome recorded
—	NCT03556696	Jun 2018 → Jun 2022	—	University Hospital, Lille	Completed	No outcome recorded
—	NCT03744949	Mar → Oct 2018	—	Ciusss de L'Est de l'Île de Montréal	Completed	No outcome recorded
—	NCT03406533	Feb → Mar 2018	—	Changhai Hospital	Terminated	No outcome recorded
—	NCT03406546	Feb → Jun 2018	—	Changhai Hospital	Terminated	No outcome recorded
—	NCT03207100	Dec 2017 → Feb 2021	—	Hong Yang	Completed	No outcome recorded
—	NCT03173339	Jun → Aug 2017	—	Keimyung University Dongsan Medical Center	Completed	No outcome recorded
—	NCT02973724	Nov 2016 → Jun 2017	substance abuse	Ajou University School of Medicine	Completed	No outcome recorded
—	NCT03389763	Jun 2016 → Jan 2018	—	Medical University of Silesia	Completed	No outcome recorded
—	NCT02683837	Apr → Nov 2016	—	University Hospital, Geneva	Withdrawn	No outcome recorded
—	NCT03508102	Aug 2015 → Sep 2016	—	West China Second University Hospital	Completed	No outcome recorded
—	NCT03037892	Jun 2015 → May 2018	—	King Hamad University Hospital, Bahrain	Completed	No outcome recorded
—	NCT02488486	May 2015 → May 2017	cardiac valvular defect	Hopital Foch	Terminated	No outcome recorded
—	NCT02455401	May 2015 → Nov 2017	strabismus	Inje University	Completed	No outcome recorded
—	NCT02429960	Apr → Sep 2015	—	University Medical Center Hamburg-Eppendorf	Completed	No outcome recorded
—	NCT02405988	Apr 2015 → Feb 2016	—	Norwegian University of Science and Technology	Completed	No outcome recorded
—	NCT02856087	Nov 2014 → Apr 2015	—	Seoul National University Hospital	Completed	No outcome recorded
—	NCT02264626	Oct 2014 → Oct 2017	acute respiratory failure	IRCCS Azienda Ospedaliero-Universitaria di Bologna	Unknown	No outcome recorded
—	NCT02245789	Sep 2014 → Feb 2015	—	Hopital Foch	Completed	No outcome recorded
—	NCT02108795	Apr 2014 → Apr 2016	delirium	Yeungnam University College of Medicine	Unknown	No outcome recorded
—	NCT02116868	Mar 2014 → Mar 2018	—	Central Hospital, Nancy, France	Completed	No outcome recorded
—	NCT02001285	Oct 2013 → Sep 2015	—	Jeju National University School of Medicine	Unknown	No outcome recorded
—	NCT02988050	Aug 2013 → Feb 2016	epilepsy	Menoufia University	Completed	No outcome recorded
—	NCT01919203	Aug 2013 → Jul 2015	respiratory system disorder	Sangjin Park	Completed	No outcome recorded
—	NCT01912118	Jul 2013 → Jun 2014	—	Leiden University Medical Center	Completed	No outcome recorded
—	NCT01880931	Jun 2013 → Nov 2014	—	Severance Hospital	Completed	No outcome recorded
—	NCT01851005	May 2013 → Feb 2014	—	Chosun University Hospital	Completed	No outcome recorded
—	NCT01733472	Jan 2013 → Feb 2014	osteoarthritis	Region Skane	Completed	No outcome recorded
—	NCT02486926	Nov 2012 → Jul 2013	—	Hallym University Medical Center	Completed	No outcome recorded
—	NCT01735019	Nov 2012 → Jul 2013	—	Yonsei University	Completed	No outcome recorded
—	NCT01720498	Oct 2012 → Jun 2013	—	Severance Hospital	Completed	No outcome recorded
—	NCT02476981	Aug 2012 → Jul 2014	—	Hallym University Medical Center	Completed	No outcome recorded
—	NCT02430389	Jul → Nov 2012	—	Northwestern University	Terminated	No outcome recorded
—	NCT02001298	Jun 2012 → Jul 2013	hypotensive disorder	Jeju National University School of Medicine	Completed	No outcome recorded
—	NCT01489137	Nov 2011 → Feb 2012	arteriovenous hemangioma/malformation, brain neoplasm	Seoul National University Hospital	Completed	No outcome recorded
—	NCT01303471	Nov 2011 → Jan 2012	—	University Hospital of Saint-Etienne	Completed	No outcome recorded
—	NCT01614535	Aug 2011 → Mar 2012	—	Yonsei University	Completed	No outcome recorded
—	NCT01351285	Apr → Oct 2011	—	Yonsei University	Completed	No outcome recorded
—	NCT01550640	Mar 2011 → Apr 2014	pregnancy disorder	Charles University, Czech Republic	Completed	No outcome recorded
—	NCT02576600	Oct 2010 → Dec 2012	—	Pr Isabelle CONSTANT	Completed	No outcome recorded
—	NCT01147757	Jun 2010 → Jun 2012	—	Yonsei University	Unknown	No outcome recorded
—	NCT01026129	Apr → Jun 2010	—	University of Montreal Hospital Centre (CHUM)	Completed	No outcome recorded
—	NCT01082458	Feb → Jul 2010	—	Yonsei University	Completed	No outcome recorded
—	NCT01043952	Jan 2010 → Mar 2012	—	Aalborg University Hospital	Terminated	No outcome recorded
—	NCT00926718	Jun 2009 → Jun 2010	laryngostenosis	St. Vincent's Medical Center	Unknown	No outcome recorded
—	NCT01604382	Sep 2008 → May 2009	osteoarthritis	Region Skane	Completed	No outcome recorded
—	NCT03378674	Jan 2008 → Jul 2012	—	Catholic University of the Sacred Heart	Completed	No outcome recorded
—	NCT00553553	Sep 2007 → May 2008	liver disorder	St Vincent's University Hospital, Ireland	Unknown	No outcome recorded
—	NCT00361686	Jan 2006 → Jan 2007	—	Rabin Medical Center	Completed	No outcome recorded
—	NCT01056224	May 2005 → Jan 2010	—	University Health Network, Toronto	Completed	No outcome recorded
—	NCT00162591	Oct 2004 → ?	—	Assistance Publique - Hôpitaux de Paris	Unknown	No outcome recorded
—	NCT00615472	Oct 2003 → Apr 2010	Parkinson disease	Columbia University	Terminated	No outcome recorded
—	NCT00326352	Jul 2003 → Jun 2005	—	University of Edinburgh	Terminated	No outcome recorded
—	NCT00434382	Oct 2002 → Dec 2003	—	Ludwig-Maximilians - University of Munich	Unknown	No outcome recorded
—	NCT00588926	—	movement disorder	Hadassah Medical Organization	Unknown	No outcome recorded

Also used as a comparator or background therapy in 340 trials

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 06 trials
Phase 0	NCT06810336 Comparator	Mar 2025 → Sep 2027 expected	brain injury, brain neoplasm	University of Virginia	Recruiting	No outcome recorded
Phase 0	NCT06205719 Background	Jun 2024 → May 2025	—	Sichuan Provincial People's Hospital	Unknown	No outcome recorded
Phase 0	NCT06241131 Background	Mar → Dec 2024	—	Sichuan Provincial People's Hospital	Unknown	No outcome recorded
Phase 0	NCT05993039 Comparator	Sep 2023 → Dec 2024	auditory system disorder	Our Lady of the Lake Hospital	Unknown	No outcome recorded
Phase 0	NCT04016740 Background	Aug 2019 → Feb 2020	coronary artery disorder, delirium	Beth Israel Deaconess Medical Center	Completed	No outcome recorded
Phase 0	NCT03958396 Comparator	Sep 2015 → Oct 2017	obstructive sleep apnea syndrome	Washington University School of Medicine	Completed	No outcome recorded

Phase 12 trials
Phase 1	NCT00455026 Comparator	Mar 2006 → Oct 2007	—	Melbourne Health	Completed	No outcome recorded
Phase 1	NCT01013558 Comparator	Sep 2004 → Dec 2007	—	Leiden University Medical Center	Completed	No outcome recorded
Phase 1/24 trials
Phase 1/2	NCT07034963 Comparator	Jun 2025 → Jun 2028 expected	adhesions of uterus, uterine polyp	The First Affiliated Hospital of Xiamen University	Active not recruiting	No outcome recorded
Phase 1/2	NCT02307721 Background	Dec 2014 → Apr 2015	—	Norwegian University of Science and Technology	Completed	No outcome recorded
Phase 1/2	NCT02029898 Comparator	Feb 2014 → Jun 2018	—	University Hospital, Rouen	Completed	No outcome recorded
Phase 1/2	NCT01713127 Comparator	Aug 2012 → Feb 2013	pulmonary immaturity	Seoul National University Hospital	Terminated	No outcome recorded
Phase 218 trials
Phase 2	NCT07372924 Comparator	Feb → Jul 2026 overdue	—	Jiangsu HengRui Medicine Co., Ltd.	Recruiting	No outcome recorded
Phase 2	NCT06096181 Comparator	Dec 2023 → Dec 2024	adolescent idiopathic scoliosis	Cedars-Sinai Medical Center	Terminated	No outcome recorded
Phase 2	NCT03066739 Comparator	Feb 2023 → Dec 2024	—	University of California, Irvine	Terminated	No outcome recorded
Phase 2	NCT05491278 Background	Aug 2022 → Jun 2023	critical illness polyneuropathy	Xiaobo Yang, MD	Completed	No outcome recorded
Phase 2	NCT04867343 Comparator	Jun 2021 → Aug 2023	—	Jiangsu HengRui Medicine Co., Ltd.	Completed	No outcome recorded
Phase 2	NCT04149626 Comparator	Jan 2020 → Dec 2021	—	Asklepieion Voulas General Hospital	Unknown	No outcome recorded
Phase 2	NCT03925779 Comparator	Jun 2019 → Dec 2020	—	Menoufia University	Completed	No outcome recorded
Phase 2	NCT03908944 Comparator	Jan 2019 → Jan 2021	—	Steven Edelstein	Withdrawn	No outcome recorded
Phase 2	NCT03979469 Comparator	Aug 2018 → Aug 2019	—	Athens General Children's Hospital "Pan. & Aglaia Kyriakou"	Completed	No outcome recorded
Phase 2	NCT03219788 Comparator	Jul → Nov 2017	—	Assiut University	Unknown	No outcome recorded
Phase 2	NCT04541719 Comparator	Apr 2017 → May 2018	—	Mansoura University	Withdrawn	No outcome recorded
Phase 2	NCT02884440 Background	Nov 2016 → May 2019	spondylolisthesis	Rennes University Hospital	Completed	No outcome recorded
Phase 2	NCT03231683 Comparator	Mar 2014 → May 2016	—	KK Women's and Children's Hospital	Completed	No outcome recorded
Phase 2	NCT01795495 Comparator	Sep 2013 → Aug 2016	idiopathic scoliosis	Nationwide Children's Hospital	Completed	No outcome recorded
Phase 2	NCT01937767 Background	Aug 2013 → Feb 2014	—	Paion UK Ltd.	Completed	No outcome recorded
Phase 2	NCT01766089 Comparator	Jan 2013 → Dec 2016	severe pre-eclampsia	Mansoura University	Completed	No outcome recorded
Phase 2	NCT02571491 Background	Jan 2012 → Feb 2014	idiopathic scoliosis	Fundació Sant Joan de Déu	Completed	No outcome recorded
Phase 2	NCT01222091 Comparator	Feb 2009 → May 2011	—	Stanford University	Completed	No outcome recorded

Phase 2/32 trials
Phase 2/3	NCT03167905 Comparator	Jun 2017 → Jul 2021 overdue	postpartum depression	KK Women's and Children's Hospital	Active not recruiting	No outcome recorded
Phase 2/3	NCT01279499 Comparator	Apr 2010 → Jun 2011	morbid obesity	University of Patras	Unknown	No outcome recorded
Phase 311 trials
Phase 3	NCT05839366 Comparator	May 2023 → Oct 2024	infectious disease with sepsis	Nanfang Hospital, Southern Medical University	Unknown	No outcome recorded
Phase 3	NCT05782894 Background	Feb → Nov 2023	—	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Completed	No outcome recorded
Phase 3	NCT05887258 Comparator	May 2022 → May 2024	—	Unai Ortega Mera	Completed	No outcome recorded
Phase 3	NCT04940689 Comparator	Jul 2021 → Aug 2024	—	University Hospital, Rouen	Completed	No outcome recorded
Phase 3	NCT04797312 Comparator	Jul 2021 → Nov 2022	local anesthetic poisoning	University Hospital, Angers	Unknown	No outcome recorded
Phase 3	NCT03883347 Comparator	Mar 2019 → Mar 2022	—	University of Athens	Unknown	No outcome recorded
Phase 3	NCT03316339 Comparator	Nov 2017 → Jan 2019	substance-related disorder	Rennes University Hospital	Terminated	No outcome recorded
Phase 3	NCT02822144 Background	Sep 2016 → Aug 2020	stroke disorder	Rennes University Hospital	Completed	No outcome recorded
Phase 3	NCT02752477 Comparator	Aug 2016 → Sep 2020	chronic pain syndrome	Ben Lim	Unknown	No outcome recorded
Phase 3	NCT03764267 Comparator	Jan 2014 → Jan 2017	breast disorder	Ain Shams University	Completed	No outcome recorded
Phase 3	NCT01375348 Comparator	Jun 2011 → Feb 2012	CGF1	University of Aarhus	Completed	No outcome recorded

Phase 4114 trials
Phase 4	NCT07479719 Comparator	Apr 2026 → Jan 2027 expected	—	Peking University First Hospital	Not yet recruiting	No outcome recorded
Phase 4	NCT07123870 Background	Jul → Oct 2025 overdue	—	Kocaeli City Hospital	Recruiting	No outcome recorded
Phase 4	NCT06958393 Comparator	May 2025 → Jan 2026 overdue	subacute delirium	Qianfoshan Hospital	Not yet recruiting	No outcome recorded
Phase 4	NCT06897696 Comparator	Apr → Oct 2025	endotheliitis	Firat University	Completed	No outcome recorded
Phase 4	NCT06816173 Background	Feb 2025 → Jan 2026 overdue	respiratory underresponsiveness to hypoxia and hypercapnia	Second Affiliated Hospital of Wenzhou Medical University	Not yet recruiting	No outcome recorded
Show all 114 trials opens the full record — a long page
Phase not applicable183 trials
—	NCT07486336 Comparator	Sep 2026 → Sep 2028 expected	cognitive disorder	Ente Ospedaliero Ospedali Galliera	Not yet recruiting	No outcome recorded
—	NCT07601256 Background	Aug 2026 → Dec 2030 expected	infectious disease with sepsis, lung disorder	Sixth Affiliated Hospital, Sun Yat-sen University	Not yet recruiting	No outcome recorded
—	NCT07665463 Comparator	Jul → Dec 2026 expected	—	Jagiellonian University	Not yet recruiting	No outcome recorded
—	NCT07659496 Background	Jun → Aug 2026 overdue	otorhinolaryngologic disease	Dicle University	Not yet recruiting	No outcome recorded
—	NCT07699523 Background	Jun 2026 → Jun 2027 expected	electroencephalographic peculiarity: fronto-precentral beta wave groups	China-Japan Friendship Hospital	Not yet recruiting	No outcome recorded
Show all 183 trials opens the full record — a long page

Press releases naming this drug 1 release

Date	Issuer	Release
2016-12-09	Daiichi Sankyo	Daiichi Sankyo and Maruishi Pharmaceutical Launch Analgesic for General Anaesthesia Remifentanil Intravenous Injection 2mg and 5mg “Daiichi Sankyo” daiichisankyo.com ↗

Evidence & citations 24 cited values

Every value below carries the sentence it was read from. 566 sources stand behind the page.

Field	Value	Cited text
Known as	Remifentanil	“When participants reach the titration endpoint (OAAS score 1 point) during the titration of propofol in the induction, the investigators stop the dosing and switch to a...” NCT04595591 ↗ 547 “The aim of this study was to investigate the pharmacodynamic profile of the innovative molecule of remifentanil (group O = Ultiva®) and two unbranded molecules (group A =...” NCT02048293 ↗ “Anesthesia was maintained with sevoflurane (Inhalation Sevoflurane, Brand: Kaiteli, Specification: 120 mL, Approval Number: National Drug Approval H20070172, Manufacturer:...” NCT07192549 ↗ “group BAL included patients who received balanced anesthesia with sevoflurane for 30 min before removal of the flap and throughout the surgery. The TCI group included patients...” PMID 27549313 ↗ Aug 2016 “Maintenance of anesthesia is with target-controlled infusion (Marsh and Minto algorithm) with propofol (Braun Medical, Germany) and remifentanil (GlaxoSmithKline, Great...” NCT01604382 ↗ “In the TIVA group (total intravenous anaesthesia group), induction and maintenance of anaesthesia will be performed using target-controlled infusion (TCI) with propofol...” NCT07325669 ↗ “Propofol and remifentanil will be infused during night-time (8 pm to 6:30 am) for ICU patients with mechanical ventilation or high-flow nasal cannula oxygen therapy (if...” NCT05718024 ↗ “Remifentanil will be administered by IV infusion and maintained at a dose of 0.025 μg/kg/min in non-mechanically ventilated patients and a dose of 0.05 μg/kg/min in...” NCT03207100 ↗ “Recently, remifentanil is commonly used short-acting opioid, and several studies have demonstrated the antitussive effect of remifentanil via effect-site target-controlled...” NCT01291849 ↗ “In the TIVA (Total Intra Venous Anesthesia) group, a combination of propofol (50-150 μg/kg/min) and remifentanil (0.02-0.2 μg/kg/min) was used for general anesthesia instead of...” NCT06558695 ↗ “Anesthesia induction was performed using propofol and remifentanil, followed by maintenance with sevoflurane to ensure adequate anesthetic depth and hemodynamic stability...” NCT07097220 ↗ “General anesthesia is induced and maintained with remimazolam (initial infusion approximately 6 mg/kg/hr for induction, then 1-2 mg/kg/hr for maintenance), along with...” NCT07265050 ↗ “initially receiving nefopam and tramadol, implementing with ketamine if patients remain painful, and then implementing with remifentanil with escalating doses in case of...” PMID 39832962 ↗ Jan 2025 “We evaluated the effects of adjunctive administration of Remifentanil, a short-acting drug, in deeply sedated patient on variation of Bispectral Index (BIS) during a fiberoptic...” PMID 22800647 ↗ Jul 2012 “Propofol group will be inducted and maintained total intravenous anesthesia with propofol 2% and remifentanil under Shinider and Minto target controlled infusion (TCI) model,...” NCT04968054 ↗ “Remifentanil, a short-acting opioid-receptor agonist with a context-sensitive half-time of 3 to 5 minutes allowing rapid emergence from anesthesia, even after an infusion of...” NCT02033629 ↗ “anaesthesia was maintained with propofol and remifentanil (0.1 μg kg-1 min-1), and primary anaesthetic namely propofol was titrated to maintain intraoperative BIS values...” NCT01304953 ↗ “After endotracheal intubation, anesthesia was maintained with 1.5-3% sevoflurane, 0.3-0.5 μg/kg/h dexmedetomidine and 2-4 μg/mL target-controlled infusion of remifentanil in...” NCT04680650 ↗ “In addition to propofol as a hypnotic and rocuronium as a muscle relaxant, patients in the conventional opioid-based group will receive the following drugs: Remifentanil and Fentanyl” NCT05485480 ↗ “target-controlled infusion (TCI) of propofol (Diprifusor, AstraZeneca) and remifentanil (Asena PK, Cardinal Health) at the target dose of 6.0 µg.ml-1 and 8.0 ηg.ml-1, respectively” NCT00792779 ↗ “Fentanyl 2mcg/kg only at induction and infusion of propofol and remifentanil for maintenance, with doses adjusted according to bispectral index indication ( BIS maintained 40-60).” NCT04976842 ↗ “Total intravenous anesthesia induced with sufentanil,etomidate,cisatracurium and midazolam and maintained with propofol,cisatracurium and remifentanil target controlled infusion” NCT03129009 ↗ “Desflurane balanced anesthesia induced with thiopental sodium, remifentanil and atracurium and maintained with remifentanil target controlled infusion and desflurane inhalation” NCT01870011 ↗ “Desflurane balanced anesthesia induced with thiopental sodium, remifentanil and atracurium and maintained with remifentanil target controlled infusion and desflurane inhalation” NCT02504138 ↗ “Use of a hypnotic("propofol 2.5mg/kg"), morphine("remifentanil1yg/kg") and curare("atracurium0.5mg/kg"), with the support of orotracheal intubation and mechanical ventilation” NCT03666949 ↗ “General anaesthesia is provided using total intravenous anaesthesia with short-acting agents, primarily propofol and remifentanil, administered by trained anaesthesiologists.” NCT07334132 ↗ “Sevoflurane group will be inducted with bolus of propofol 1% and maintained with sevofulrane as inhalation and TCI Minto model of remifentanil for general anesthesia.” NCT05019222 ↗ “Along with induction, propofol at a dose of 6-10 mg/kg/hour and remifentanil infusion at a dose of 0.3-0.4 mcg/kg/min were started for the maintenance of anesthesia.” NCT04310748 ↗ “For induction and maintenance of anesthesia, total intravenous anesthesia is performed using continuous intravenous infusion of remimazolam and remifentanil.” NCT05375747 ↗ “TCI propofol 3-3.5μg/ml, TCI remifentanil 1-2ng/ml, sufentanil 0.3μg/kg iv, midazolam 0.05mg/kg iv, and rocuronium 0.6mg/kg iv after loss of consciousness.” NCT06120439 ↗ “During the operation, patients are treated with remifentanil, cisatracurium, and desflurane inhalation at 0.5-1.0 minimum alveolar concentration (MAC).” NCT05550714 ↗ “Propfol group will be started and maintained total intravenous anesthesia with propofol and remifentanil under target controlled infusion (TCI) model.” NCT04994704 ↗ “Anesthesia was maintained with propofol (5 mg/kg/h) and remifentanil (0.01 µg/kg/min) first, and then adjusted according to the depth of anesthesia.” NCT06367218 ↗ “The remifentanil administration will be piloted by the ANI, as well as the prophylactic administration of morphine at the end of the intervention.” NCT03618082 ↗ “Propofol (induction: 1.0-2.0 mg/kg. infusion: 3-5 mg/kg/hour) + Remifentanil (induction: 3-5 mcg/kg, infusion: 0.5 mcg/kg/min) given intravenously” NCT05706844 ↗ “Remifentanil will be administered via effect-site target-controlled infusion (TCI), with a concentration effect (Ce) ranging from 2 to 8 ng/ml.” NCT07614607 ↗ “TIVA: General anesthesia will be based on Remifentanil and Propofol (TIVA-TCI), titrated to achieve bispectral index (BIS) between 40 and 60.” NCT01833715 ↗ “Standard of Care patients will be given an infusion of remifentanil 0.15-0.25 mcg/kg/min as part of their intraoperative anesthetic regimen.” NCT03908944 ↗ “Remifentanil is a short-acting opioid with rapid onset and offset because it is metabolized by non-specific blood and tissue esterases.” NCT06727435 ↗ “The Desflurane was inhaled at a starting concentration of 1 MAC, and remifentanil 0.1 μg/kg/min was continuously pumped intravenously.” NCT06241131 ↗ “maintenance anesthetic consisting of remifentanil and sevoflurane (Sevoflurane Group) or remifentanil and propofol (Propofol Group).” PMID 24500661 ↗ Feb 2014 “Anesthesia based on inhalation of 1-1.5 Minimal Alveolar Concentration of Isoflurane with the addition of infusion of remifentanil” NCT01397331 ↗ “Anaesthesia is induced (1-2 mg/kg) and maintained (5-7 mg/kg/h) with propofol and remifentanil (1 µg/kg and 0,2-0,4 µg/kg/min).” NCT02217319 ↗ “In the TIVA group,anesthesia is induced and maintained by effect-site target controlled infusion of propofol and remifentanil.” NCT02813044 ↗ “Remimazolam group receive total intravenous anesthesia using remimazolam besylate and remifentanil during rigid bronchoscopy.” NCT05835713 ↗ “Four measurements will be obtained at different target plasma concentrations of remifentanil(Ultiva®): 0, 1, 2, and 3 ng/mL.” NCT07568405 ↗ “Anesthesia induction will include 2 mg midazolam, 2-2.5 mg/kg propofol, 0.6-0.9 mg/kg rocuronium, and 1 μg/kg remifentanil.” NCT07271472 ↗ “Remifentanil is infused during anesthesia, and target-controlled infusion (TCI) is performed according to the Minto model.” NCT05076903 ↗ “Propofol, sufentanil and rocuronium were used during induction, and propofol and remifentanil were used during maintenance” NCT06990763 ↗ “followed by continuous infusion of propofol at 4-12 mg/kg/h and remifentanil at 3-6 µg/kg/h until the end of the surgery” NCT07062601 ↗ “This study tries to find the best drug concentration of Remifentanil, ALVOGEN® (2 mg/vial) in Uterine Fibroid Ablation.” NCT06640738 ↗ “The inhalation group will be maintained with inhaled sevoflurane and a continuous intravenous infusion of remifentanil.” NCT07601256 ↗ “In TIVA group, anesthesia will be maintained by propofol and remifentanil infusion under target controlled infusion.” NCT05951842 ↗ “Intraoperative analgesia will be administered with conventional opioid drugs such as sufentanil and remifentanil.” NCT06607029 ↗ “using intraoperative opioids such as fentanyl or remifentanil, administered according to institutional protocols” NCT07310524 ↗ “After induction, anesthesia will be maintained with 0.7-1.0 MAC desflurane and 0.05-0.3 μg/kg/min remifentanil.” NCT05088252 ↗ “Intubation is performed 3 minutes after administration of remifentanil 1-2 mcg / kg and rocuronium 0.6 mg / kg.” NCT03447691 ↗ “Maintenance will be achieved using remifentanil (Ultiva®) infusion at 0.1-0.3 µg/kg/min and 1 MAC sevoflurane.” NCT07105839 ↗ “After induction, anesthesia will be maintained with 0.7-1.0 MAC desflurane and remifentanil 0.05-0.2 μg/kg/min” NCT05465330 ↗ “Minto Model in Effect Site Mode for Target-Controlled Infusion of Remifentanil During Cardiopulmonary Bypass” NCT02566733 ↗ “Propfol group will be started and maintained total intravenous anesthesia with propofol and remifentanil .” NCT05016518 ↗ “Patients will receive propofol-based TIVA with propofol and remifentanil TCI (target controlled infusion)” NCT05280236 ↗ “This arm is composed of Remifentanil hydrochloride and postoperative rescue analgesia will be morphine.” NCT05887258 ↗ “Sevoflurane 0.7-1.3MAC + Remifentanil 0.1-0.2ug/kg/min + Propofol 2mg/kg/h for anesthesia maintenance” NCT01084200 ↗ “Continuous infusion of remifentanil at 0.05 ~ 2 mcg/kg/min with sevoflurane concentration of 1 MAC” NCT01634594 ↗ “General anesthesia using classical GABAergic-drugs such as propofol, remifentanil and rocuronium.” NCT07486336 ↗ “General anesthesia was maintained with a continuous infusion of remifentanil (5-15 μg kg-1 h-1)” NCT06199011 ↗ “Sufentanil 0.2-0.3μg/kg for induction and remifentanil 0.05-0.15μg/kg/min for maintenance” NCT05242081 ↗ “both groups received a constant infusion of remifentanil at a rate of 0.05-0.4 μg/kg/min” NCT06816173 ↗ “Short-acting anesthetics, such as propofol and remifentanil might favor this objective.” PMID 23774117 ↗ Jan 2014 “Traditional general anesthetic technique utilizing sufentanil, fentanyl or remifentanil” NCT02752477 ↗ “propofol 5-8 mg/kg/h and remifentanil 5-10 µg/kg/h will be administered to all patients” NCT06897696 ↗ “Anesthesia induction and maintenance will be performed with ciprofol and remifentanil.” NCT07328958 ↗ “3 µg/kg of remifentanil and 10 ml of isotonic sodium chloride for the double blind” NCT01910285 ↗ “Induction PROPOFOL 10mg/ml REMIFENTANIL 50 μg/ml CISATRACURIUM 2mg/ml if necessary” NCT02884440 ↗ “General anaesthesia with Propofol (2mg/kgKG) and Remifentanil (0,1-0,4 µg/kg/min)” NCT03081897 ↗ “ICU stay sedation: Remifentanil infusion, until removal of the endotracheal tube.” NCT04894864 ↗ “anesthesia is maintained with desflurane and remifentanil (Desflurane group)” NCT01760018 ↗ “Maintenance of anesthesia: Continuous infusion of propofol and remifentanil” NCT04507165 ↗ “In this group, participants are sedated with remimazolam and remifentanil.” NCT06187896 ↗ “continuous intravenous infusion of propofol and remifentanil was started” NCT06493396 ↗ “Remifentanil is the first ultra-short acting opioid with a rapid onset.” NCT01030510 ↗ “During surgery, 2-6 mg/kg/h propofol, 0.2-1.0 μg/kg/min remifentanil” NCT07603596 ↗ “Remifentanil continuous infusion of 4 to 9 ug/kg/h for analgesia.” NCT05491278 ↗ “Patients undergo anesthesia with xenon (remifentanil with xenon).” NCT01404819 ↗ “Remifentanil will be infused intraoperatively at 0.2 ㎍/㎏/min.” NCT01189721 ↗ “Continuous intravenous remifentanil O.2μg/(kg•h) and propofol” NCT02289391 ↗ “remifentanil 2 ng/ml TCI end-organ concentration” NCT00244517 ↗ “Light anesthesia with propofol and remifentanil” NCT07479719 ↗ “intravenous anesthesia (propofol-remifentanil)” NCT04077827 ↗ “utilizing a propofol-remifentanil combination” NCT07123870 ↗ “Remifentanil (0.5-2 micrograms/kg/dose)” NCT04073173 ↗ “0.2 mL/kg/h remifentanil infusion” NCT05752799 ↗ “Remifentanil: 0.05-0.2 mcg/Kg/h” NCT07558226 ↗ “remifentanil (4-8㎍ / kg / hr)” NCT04063046 ↗ “Rémifentanil + Kétamine” NCT01560390 ↗ NCT01901575 ↗ NCT02104297 ↗ NCT06581731 ↗ NCT01240109 ↗ NCT02484859 ↗ NCT07363681 ↗ NCT06583811 ↗ NCT02967029 ↗ NCT00158873 ↗ NCT00202722 ↗ NCT00213239 ↗ NCT02486926 ↗ NCT01052324 ↗ NCT02488486 ↗ NCT07307625 ↗ NCT03124082 ↗ NCT02486328 ↗ NCT03868111 ↗ NCT04301895 ↗ NCT07181564 ↗ NCT07695220 ↗ NCT04529135 ↗ NCT01275911 ↗ NCT00681174 ↗ NCT07182097 ↗ NCT05391555 ↗ NCT02655380 ↗ NCT01563939 ↗ NCT02107170 ↗ NCT04287426 ↗ NCT02683837 ↗ NCT02973724 ↗ NCT06138574 ↗ NCT00405522 ↗ NCT05789992 ↗ NCT01412632 ↗ NCT01013558 ↗ NCT01079312 ↗ NCT03883347 ↗ NCT02093143 ↗ NCT07699523 ↗ NCT05384665 ↗ NCT07035301 ↗ NCT02428283 ↗ NCT07034963 ↗ NCT07033442 ↗ NCT02108795 ↗ NCT04734418 ↗ NCT02089178 ↗ NCT03864094 ↗ NCT00801047 ↗ NCT02481791 ↗ NCT04260659 ↗ NCT01795495 ↗ NCT07337135 ↗ NCT01269918 ↗ NCT04753515 ↗ NCT01082458 ↗ NCT02703090 ↗ NCT07304206 ↗ NCT06331663 ↗ NCT06096181 ↗ NCT02709473 ↗ NCT03517735 ↗ NCT02179294 ↗ NCT02111265 ↗ NCT04541719 ↗ NCT01147757 ↗ NCT02637726 ↗ NCT07336628 ↗ NCT02712528 ↗ NCT04236323 ↗ NCT05279898 ↗ NCT02635802 ↗ NCT02429960 ↗ NCT06289829 ↗ NCT02430389 ↗ NCT03643796 ↗ NCT03066739 ↗ NCT01809041 ↗ NCT03705728 ↗ NCT05876039 ↗ NCT00391105 ↗ NCT01998217 ↗ NCT06793150 ↗ NCT02717780 ↗ NCT03065309 ↗ NCT02631135 ↗ NCT02113150 ↗ NCT02078583 ↗ NCT04226443 ↗ NCT00693160 ↗ NCT01451840 ↗ NCT01452880 ↗ NCT00555984 ↗ NCT02432677 ↗ NCT07665645 ↗ NCT01026129 ↗ NCT07665463 ↗ NCT05993039 ↗ NCT01419405 ↗ NCT07002801 ↗ NCT04465773 ↗ NCT01025245 ↗ NCT07660861 ↗ NCT07660562 ↗ NCT04553536 ↗ NCT07659496 ↗ NCT01569048 ↗ NCT02625181 ↗ NCT02733835 ↗ NCT02400879 ↗ NCT02334046 ↗ NCT01766089 ↗ NCT01998165 ↗ NCT03231683 ↗ NCT06305221 ↗ NCT05654064 ↗ NCT04204967 ↗ NCT01652586 ↗ NCT02116868 ↗ NCT01175746 ↗ NCT06403670 ↗ NCT05866315 ↗ NCT07649746 ↗ NCT06658132 ↗ NCT03539003 ↗ NCT04670471 ↗ NCT00665119 ↗ NCT06162390 ↗ NCT02619578 ↗ NCT02117401 ↗ NCT04940689 ↗ NCT00811837 ↗ NCT01830296 ↗ NCT02619032 ↗ NCT06033729 ↗ NCT03247998 ↗ NCT05641909 ↗ NCT01474213 ↗ NCT06283836 ↗ NCT05754762 ↗ NCT05864404 ↗ NCT01693185 ↗ NCT05125328 ↗ NCT00436345 ↗ NCT01833819 ↗ NCT02067936 ↗ NCT05639686 ↗ NCT04455711 ↗ NCT04940273 ↗ NCT01139671 ↗ NCT03219788 ↗ NCT06788743 ↗ NCT04178785 ↗ NCT02664922 ↗ NCT07640243 ↗ NCT02309879 ↗ NCT02307721 ↗ NCT01702389 ↗ NCT03117894 ↗ NCT00706277 ↗ NCT00815048 ↗ NCT04935541 ↗ NCT01572454 ↗ NCT00455026 ↗ NCT02602002 ↗ NCT03861377 ↗ NCT03283020 ↗ NCT00553553 ↗ NCT03283150 ↗ NCT06810336 ↗ NCT01762332 ↗ NCT01381627 ↗ NCT05624424 ↗ NCT01477892 ↗ NCT03622502 ↗ NCT03540875 ↗ NCT02123355 ↗ NCT01714388 ↗ NCT05003570 ↗ NCT01043952 ↗ NCT01851005 ↗ NCT05717361 ↗ NCT01592162 ↗ NCT02597699 ↗ NCT01761149 ↗ NCT04149626 ↗ NCT02593942 ↗ NCT06962085 ↗ NCT06312657 ↗ NCT02595476 ↗ NCT01732666 ↗ NCT00710086 ↗ NCT06958393 ↗ NCT00886106 ↗ NCT00615472 ↗ NCT03744949 ↗ NCT01234194 ↗ NCT03089905 ↗ NCT02291094 ↗ NCT02349152 ↗ NCT02289586 ↗ NCT04333992 ↗ NCT03613792 ↗ NCT04797312 ↗ NCT01550640 ↗ NCT02287181 ↗ NCT00588926 ↗ NCT01191645 ↗ NCT00567957 ↗ NCT05785234 ↗ NCT02001285 ↗ NCT02001298 ↗ NCT02164734 ↗ NCT06444997 ↗ NCT01759589 ↗ NCT03756233 ↗ NCT03901716 ↗ NCT03316339 ↗ NCT03756961 ↗ NCT06785987 ↗ NCT02353182 ↗ NCT04364945 ↗ NCT01375348 ↗ NCT05004519 ↗ NCT00534586 ↗ NCT01733472 ↗ NCT03325335 ↗ NCT00421720 ↗ NCT02054468 ↗ NCT06454292 ↗ NCT04117009 ↗ NCT03330782 ↗ NCT02799589 ↗ NCT04104334 ↗ NCT02053818 ↗ NCT03905837 ↗ NCT01871935 ↗ NCT00349245 ↗ NCT02271555 ↗ NCT02440204 ↗ NCT01259648 ↗ NCT04105946 ↗ NCT01872754 ↗ NCT01872884 ↗ NCT05594407 ↗ NCT03763305 ↗ NCT07462949 ↗ NCT02576600 ↗ NCT03764267 ↗ NCT01735669 ↗ NCT02809378 ↗ NCT01880931 ↗ NCT03912740 ↗ NCT03096730 ↗ NCT05345574 ↗ NCT00434382 ↗ NCT05839366 ↗ NCT01735019 ↗ NCT02264626 ↗ NCT02818387 ↗ NCT03041948 ↗ NCT02571491 ↗ NCT05782894 ↗ NCT03041935 ↗ NCT02134093 ↗ NCT02819375 ↗ NCT00789386 ↗ NCT03508102 ↗ NCT05344911 ↗ NCT00627081 ↗ NCT01885364 ↗ NCT02822144 ↗ NCT00474071 ↗ NCT04081909 ↗ NCT02476981 ↗ NCT01365923 ↗ NCT02826902 ↗ NCT01201499 ↗ NCT03037892 ↗ NCT01974648 ↗ NCT05951686 ↗ NCT03098875 ↗ NCT02499445 ↗ NCT02364765 ↗ NCT00335972 ↗ NCT01628562 ↗ NCT01895348 ↗ NCT01627873 ↗ NCT05026125 ↗ NCT06564857 ↗ NCT04059978 ↗ NCT04435925 ↗ NCT03378674 ↗ NCT06003218 ↗ NCT02989597 ↗ NCT02043366 ↗ NCT03132519 ↗ NCT00641563 ↗ NCT04492813 ↗ NCT01456299 ↗ NCT03173339 ↗ NCT02412150 ↗ NCT01752959 ↗ NCT01102101 ↗ NCT05572723 ↗ NCT00326859 ↗ NCT03783676 ↗ NCT00785863 ↗ NCT01972230 ↗ NCT00730054 ↗ NCT02929095 ↗ NCT03029715 ↗ NCT07094165 ↗ NCT06205719 ↗ NCT00326352 ↗ NCT03389763 ↗ NCT04974060 ↗ NCT02856087 ↗ NCT02243254 ↗ NCT01545297 ↗ NCT01912118 ↗ NCT02245789 ↗ NCT01915108 ↗ NCT01103193 ↗ NCT01713127 ↗ NCT04026074 ↗ NCT05936671 ↗ NCT01048398 ↗ NCT06237101 ↗ NCT03401606 ↗ NCT05215834 ↗ NCT07571473 ↗ NCT02143362 ↗ NCT03406533 ↗ NCT01056224 ↗ NCT03406546 ↗ NCT00772616 ↗ NCT01919203 ↗ NCT01489072 ↗ NCT05217238 ↗ NCT01920113 ↗ NCT05686863 ↗ NCT04016740 ↗ NCT02988050 ↗ NCT02454868 ↗ NCT04906889 ↗ NCT03417180 ↗ NCT05551910 ↗ NCT03417206 ↗ NCT06617039 ↗ NCT02455401 ↗ NCT01351285 ↗ NCT03498820 ↗ NCT01303627 ↗ NCT01489137 ↗ NCT05548465 ↗ NCT07532733 ↗ NCT00667043 ↗ NCT02031016 ↗ NCT02147678 ↗ NCT03925779 ↗ NCT02224443 ↗ NCT01924234 ↗ NCT03135795 ↗ NCT01924871 ↗ NCT00757198 ↗ NCT01304342 ↗ NCT02029898 ↗ NCT04867343 ↗ NCT04005599 ↗ NCT01350037 ↗ NCT00522587 ↗ NCT00315536 ↗ NCT02536690 ↗ NCT03443518 ↗ NCT03805568 ↗ NCT01720615 ↗ NCT03928366 ↗ NCT02473354 ↗ NCT01614535 ↗ NCT01003028 ↗ NCT02884310 ↗ NCT03807011 ↗ NCT02151305 ↗ NCT06091904 ↗ NCT03812003 ↗ NCT02457442 ↗ NCT03996148 ↗ NCT06524596 ↗ NCT02405988 ↗ NCT07372924 ↗ NCT03556696 ↗ NCT02405689 ↗ NCT02379715 ↗ NCT01931683 ↗ NCT03994146 ↗ NCT01222091 ↗ NCT03110653 ↗ NCT03451227 ↗ NCT01491009 ↗ NCT03152981 ↗ NCT02212340 ↗ NCT07556172 ↗ NCT03983915 ↗ NCT06260046 ↗ NCT03983889 ↗ NCT01937104 ↗ NCT01495377 ↗ NCT02528825 ↗ NCT02898792 ↗ NCT02382354 ↗ NCT01542099 ↗ NCT03979469 ↗ NCT01937767 ↗ NCT07092046 ↗ NCT02208778 ↗ NCT02208505 ↗ NCT05527314 ↗ NCT03817359 ↗ NCT02527083 ↗ NCT00778505 ↗ NCT01248871 ↗ NCT02464722 ↗ NCT04372342 ↗ NCT06531837 ↗ NCT01053611 ↗ NCT01746641 ↗ NCT01229527 ↗ NCT05243940 ↗ NCT01015651 ↗ NCT04409964 ↗ NCT05014711 ↗ NCT05244538 ↗ NCT02206022 ↗ NCT07092384 ↗ NCT05468671 ↗ NCT01152476 ↗ NCT01015482 ↗ NCT01152515 ↗ NCT02922660 ↗ NCT00611195 ↗ NCT06539013 ↗ NCT00926718 ↗ NCT03960801 ↗ NCT03958396 ↗ NCT03143972 ↗ NCT01947114 ↗ NCT02202239 ↗ NCT02518789 ↗ NCT01720498 ↗
Known as	Extubation U	ClinicalTrials.gov intervention name — accepted as the source's own label NCT02711904 ↗
Known as	Fada Remifentanilo	“The aim of this study was to investigate the pharmacodynamic profile of the innovative molecule of remifentanil (group O = Ultiva®) and two unbranded molecules (group A =...” NCT02048293 ↗
Known as	GI 87084B	ChEMBL registry synonym — accepted as the source's own label CHEMBL1005 ↗
Known as	GI 87084X	ChEMBL registry synonym — accepted as the source's own label CHEMBL1005 ↗
Known as	IDS-NR-005	ChEMBL registry synonym — accepted as the source's own label CHEMBL1005 ↗
Known as	Ramifentanyl	ChEMBL registry synonym — accepted as the source's own label CHEMBL1005 ↗
Known as	REM	“The aim of this study was to evaluate the efficacy of remifentanil (REM) versus dexmedetomidine (DEX) for treatment of cardiac surgery (CS) patients with moderate to severe NIV...” PMID 33209418 ↗ Oct 2020
Known as	remi	“Dexmedetomidine/remifentanil (dex/remi group) and midazolam/remifentanil (mida/remi group) were infused 7 days apart.” PMID 17056949 ↗ Nov 2006
Known as	Remifentanil ALVOGEN	“Remifentanil ALVOGEN®” NCT06640738 ↗
Known as	remifentanil HCl	“Intra-operative intravenous remifentanil HCl at titratable dose range 0.1-0.25 micrograms/kilogram/minute until start of wound closure” NCT00553553 ↗
Known as	Remifentanil Hydrochloride	“Morphine hydrochloride, remifentanil hydrochloride” NCT00553553 ↗ 6 “Remifentanil Hydrochloride for Injection” NCT07372924 ↗ “Drug: Remifentanil Hydrochloride” NCT05391555 ↗ “Drug: Remifentanil Hydrochloride” NCT04409964 ↗ “Drug: Remifentanil Hydrochloride” NCT02967029 ↗ “Drug: Remifentanil Hydrochloride” NCT04906889 ↗ NCT02999126 ↗
Known as	remifentanil hydrochloride (JNJ-268229)	“remifentanil hydrochloride (JNJ-268229)” NCT01998165 ↗
Known as	remifentanil hydrochloride for injection	“remifentanil hydrochloride for injection” NCT04974060 ↗
Known as	Remifentanil Laboratorios Chalver de Colombia S.A.	“The aim of this study was to investigate the pharmacodynamic profile of the innovative molecule of remifentanil (group O = Ultiva®) and two unbranded molecules (group A =...” NCT02048293 ↗
Known as	Remifentanil: Ultiva	“remifentanil (ultiva)” NCT01915108 ↗ 3 “remifentanil (ultiva)” NCT02108795 ↗ “remifentanil (ultiva)” NCT01919203 ↗ “Remifentanil: Ultiva” NCT00627081 ↗
Known as	Remifentanilo	ChEMBL registry synonym — accepted as the source's own label CHEMBL1005 ↗
Known as	Remifentanyl	“Compare the opioid based anesthesia with Fentanyl and Remifentanyl to opioid free anesthesia with dexmedetomidine and lidocaine and their effect on postoperative pain.” NCT03417193 ↗ 10 NCT01279499 ↗ NCT02602743 ↗ NCT01998685 ↗ NCT00361686 ↗ NCT00419601 ↗ NCT03507634 ↗ NCT01303471 ↗ NCT03434691 ↗ NCT00741351 ↗ NCT01930747 ↗
Known as	Ultiva	“Remifentanil (Ultiva®; Glaxo-Smith-Kline; Vienna, Austria) will be applied intravenously during 60 minutes through a dedicated infusion pump (TCI Alaris PK Syringe Pump,...” NCT00886106 ↗ 14 “Remifentanil (Ultiva; Glaxo-Smith-Kline; Vienna, Austria) will be applied intravenously during 60 minutes through a dedicated infusion pump (TCI Alaris PK Syringe Pump,...” NCT01102101 ↗ “The aim of this study was to investigate the pharmacodynamic profile of the innovative molecule of remifentanil (group O = Ultiva®) and two unbranded molecules (group A =...” NCT02048293 ↗ “Remifentanil (Ultiva, Glaxo SmithKline, Turkey) infusion was started at a dose of 0.05 µg/kg/min-1, 10 minutes before the start of the surgery as baseline infusion and...” NCT04935541 ↗ “Remifentanil (Ultiva), a 4-anilidopiperidine derivative of fentanyl, is an ultra-short-acting micro-opioid receptor agonist indicated to provide analgesia and sedation in...” PMID 16526829 ↗ 2006 “For patients randomized to arm 2, we will inject 30 μg of intravenous Remifentanil (Ultiva®) followed by Xylocaine 1% in a 10 ml bolus (10 mg / ml).” NCT02597699 ↗ “Remifentanil (Ultiva ®; Glaxo-Smith-Kline; Vienna, Austria) at an initial dose of 0.24 µg kg-1 min-1 will be applied iv during 60 minutes.” NCT00789386 ↗ “Four measurements will be obtained at different target plasma concentrations of remifentanil(Ultiva®): 0, 1, 2, and 3 ng/mL.” NCT07568405 ↗ “Drug: Remifentanil (Ultiva). Intraoperative intravenous infusion of remifentanil 0.5-1 μg/kg/min for up to 1 h.” NCT02619032 ↗ “Maintenance will be achieved using remifentanil (Ultiva®) infusion at 0.1-0.3 µg/kg/min and 1 MAC sevoflurane.” NCT07105839 ↗ “High dose remifentanil (Ultiva,Glaxosmithkline, UK)” NCT02455401 ↗ “Remifentanyl, Ultiva, GlaxoSmithKline” NCT01279499 ↗ “Drug: Remifentanil Injection [Ultiva]” NCT04940273 ↗ “Remifentanil, Ultiva®” NCT04465773 ↗ NCT03167905 ↗
Known as	Ultiva (remifentanil)	“Ultiva (remifentanil)” NCT01375348 ↗
Action	Activate	“Remifentanil is a μ-opioid receptor agonist” NCT00567957 ↗ 1 “Mu opioid receptor agonist” CHEMBL1005 ↗
Modality	Small molecule	“Remifentanil is an amidopiperidine derivative with unique pharmacokinetic properties.” NCT00335972 ↗
Route	Other	“intravenius use” NCT00315536 ↗
Target	OPRM1	“Mu opioid receptor agonist” CHEMBL1005 ↗