The Effect of Dexmedetomidine for Emergence Cough

Completed 48 enrolled Ajou University School of Medicine

RandomizedParallel-groupDouble-blindPrevention

Summary

Dexmedetomidine or remifentanil are effective in attenuating cough during peri-extubation period after general anesthesia. The purpose of this study was to investigate the effect of dexmedetomidine on the remifentanil concentration for the cough suppression during anesthetic emergence.

Timeline

Start: 2018-08-16
Primary completion: 2019-03-22
Completion: 2019-03-27

Publications

Kim HY, Kwak HJ, Lee D, Lee JH, Min SK, Kim JY. Comparison of remifentanil concentrations with and without dexmedetomidine for the prevention of emergence cough after nasal surgery: a randomized double-blinded trial. BMC Anesthesiol. 2021 May 4;21(1):136. doi: 10.1186/s12871-021-01358-x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexmedetomidine	Other / unclassified	0.5 ug/kg	—
Subject	Remifentanil	Small molecule	2 ng/ml	—

Indications

No indication recorded.