Evaluation of the Potentiating Effect of tDCS on Opioid Analgesia of Pain Threshold in Humans

Phase 2 Unknown 48 enrolled Hospital de Clinicas de Porto Alegre

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to evaluate the potential additive effect of tDCS compared to placebo-sham in opioid analgesia on pain thresholds in nociceptive experimental model in healthy volunteers .

Timeline

Start: 2014-07
Primary completion: 2015-12
Completion: 2016-04

Publications

Braulio G, Passos SC, Leite F, Schwertner A, Stefani LC, Palmer ACS, Torres ILS, Fregni F, Caumo W. Effects of Transcranial Direct Current Stimulation Block Remifentanil-Induced Hyperalgesia: A Randomized, Double-Blind Clinical Trial. Front Pharmacol. 2018 Feb 19;9:94. doi: 10.3389/fphar.2018.00094. eCollection 2018.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Remifentanil	Small molecule	0.06 ug/kg	Intravenous

Indications

No indication recorded.