Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA
Summary
The goal of this randomized clinical trial is to investigate the postoperative recovery following hip and knee arthroplasty procedures depending on the use of either spinal anaesthesia (SA) or general anaesthesia (GA). The main questions are: * Are more patients able to be safely mobilized within 6 hours postoperatively when using GA compared to SA? * Does postoperative pain, nausea and vomiting, dizzyness, occurence of delirium and urinary retention differ between the anaesthetic methods? Participants, scheduled for total hip, total knee and unicomartmental knee arthroplasty, will be randomized to recieve spinal anaesthesia or general anaesthesia in relation to surgery. At 6 hours postoperatively a physiotherapist will conduct a 5-meter walking test to evaluate whether the participant can be safely mobilized.
Timeline
- Start
- 2023-03-06
- Primary completion
- 2025-04-06
- Completion
- 2025-04-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 10 mg | Intrathecal |
| Subject | Propofol | Small molecule | 3 mg/kg | Intravenous |
| Subject | Propofol | Small molecule | 5 mg/kg | Intravenous |
| Subject | Remifentanil | Small molecule | 0.5 ug/kg | Intravenous |