drugset / Trial / NCT05242081
Study on Opioid-free Anesthesia Protocol With S-ketamine and Propofol
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study was to observe the effects of opioid-free anesthesia with S-ketamine on postoperative analgesia and perioperative hemodynamics in short surgical operations, and to explore the effects of S-ketamine on postoperative awakening time and extubation time, nausea and vomiting, hypoxemia, and delirium.
Timeline
- Start
- 2022-07
- Primary completion
- 2022-12
- Completion
- 2023-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esketamine | Other / unclassified | 0.2 mg/kg | — |
| Subject | Remifentanil | Small molecule | 0.05 ug/kg | — |
| Subject | Remifentanil | Small molecule | 0.15 ug/kg | — |
| Comparator | Sufentanil | Other / unclassified | 0.2 ug/kg | — |
| Comparator | Sufentanil | Other / unclassified | 0.3 ug/kg | — |