Drugs / Sufentanil
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Sufentanil

Other / unclassified targets OPRM1 via activation

Developed for
chronic pain syndrome · delirium · neuropathy, painful · sickle cell disease · bowel dysfunction · cancer · cardiovascular disorder · disease of bone structure
+13 more · obstetric disorder · pain agnosia · paralytic ileus · pregnancy disorder · acute respiratory distress syndrome · anxiety · cardiac valvular defect · local anesthetic poisoning · pectus excavatum · postpartum depression · pulpitis · subacute delirium · traumatic brain injury
Investigated by
Talphera, Inc · Fudan University · Seoul National University Hospital · Yonsei University · Assistance Publique - Hôpitaux de Paris · Beijing Tiantan Hospital
+89 more · Cessatech A/S · Peking University First Hospital · Tongji Hospital · University Hospital, Montpellier · University Hospital, Toulouse · University of Minnesota · Affiliated Hospital of Jiaxing University · Ankara City Hospital Bilkent · Anqing Municipal Hospital · Beijing Friendship Hospital · Beijing Tongren Hospital · Bent Gymoese Jorgensen · Brigham and Women's Hospital · Brugmann University Hospital · C. R. Bard · Centre Hospitalier Sud Francilien · Centre Hospitalier Universitaire Dijon · Centre Hospitalier Universitaire Saint Pierre · Centre Hospitalier Universitaire de Nice · Centre Hospitalier Universitaire de Tivoli · China International Neuroscience Institution · China-Japan Friendship Hospital · Danish University of Pharmaceutical Sciences · Deng Dongrui · Dr Madeleine Wilwerth · Eye & ENT Hospital of Fudan University · Fondation Apicil · Fondation Lenval · Frank Guyette · Fujian Provincial Hospital · Fundación Pública Andaluza Progreso y Salud · German Federal Ministry of Education and Research · Gia Dinh People Hospital · GlaxoSmithKline · Guangzhou Institute of Respiratory Disease · Hopital Foch · Hospices Civils de Lyon · Hospital Central do Funchal · Huazhong University of Science and Technology · Indiana University · Jin Ni · Jun Wang · Kangbuk Samsung Hospital · Karolinska Institutet · Labtec GmbH · Ludwig-Maximilians - University of Munich · Makassed General Hospital · Montefiore Medical Center · Nanfang Hospital, Southern Medical University · Nanjing Maternity and Child Health Care Hospital · Northern Jiangsu People's Hospital · Peking University People's Hospital · Peking University Shenzhen Hospital · Qianfoshan Hospital · Reims University Hospital · RenJi Hospital · Rigshospitalet, Denmark · Rush University Medical Center · SFMU · Second Affiliated Hospital of Xi'an Jiaotong University · Second Hospital of Shanxi Medical University · Shanghai First Maternity and Infant Hospital · Shanghai Jiao Tong University School of Medicine · Shengjing Hospital · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · The Brooklyn Hospital Center · Tianjin First Central Hospital · U.S. Army Medical Research and Development Command · United States Department of Defense · University Hospital Hradec Kralove · University Hospital, Bordeaux · University Hospital, Clermont-Ferrand · University Hospital, Geneva · University Hospital, Ghent · all 95 on the full record

Regulatory milestones approvals, filings & regulatory actions · 3 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Zalviso 2015-09-18 europa.eu
Label expansion US (FDA) SUFENTA PRESERVATIVE FREE 1993-03-19 fda.gov
Approved US (FDA) SUFENTA PRESERVATIVE FREE 1984-05-04 fda.gov

Trials 112 · started per year

today
US approved 1984
EU approved 2015
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT07603596 May 2026 → Apr 2028 expected delirium, digestive system neoplasm Qianfoshan Hospital Not yet recruiting No outcome recorded
Phase 1 NCT02082236 May 2014 Talphera, Inc Completed No outcome recorded
Phase 1 NCT01761565 Jan → Feb 2013 Talphera, Inc Completed No outcome recorded
Phase 1 NCT01721070 Nov → Dec 2012 Talphera, Inc Completed No outcome recorded
Phase 1 NCT01639729 Jul 2012 Talphera, Inc Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT04959812 Mar 2022 → Sep 2023 University of Texas Southwestern Medical Center Completed No outcome recorded
Phase 1/2 NCT01012999 Nov 2009 → Mar 2011 University of Utah Terminated No outcome recorded
Phase 211 trials
Phase 2 NCT06968546 Feb 2026 → Mar 2028 expected disease of bone structure Fondation Lenval Not yet recruiting No outcome recorded
Phase 2 NCT04897750 Aug 2021 → May 2022 pain agnosia Cessatech A/S Completed No outcome recorded
Phase 2 NCT02962830 Apr 2017 → May 2024 University Hospital, Lille Completed No outcome recorded
Phase 2 NCT01710345 Oct 2012 → Feb 2013 Talphera, Inc Completed No outcome recorded
Phase 2 NCT01047241 Apr 2010 → Feb 2013 Danish University of Pharmaceutical Sciences Completed No outcome recorded
Phase 2 NCT00943566 Jan → Dec 2010 chronic pain syndrome Labtec GmbH Withdrawn No outcome recorded
Phase 2 NCT00833040 Apr 2009 → Mar 2010 cancer Talphera, Inc Completed No outcome recorded
Phase 2 NCT00859313 Apr → Aug 2009 neuropathy, painful Talphera, Inc Completed No outcome recorded
Phase 2 NCT00718081 Aug 2008 → Mar 2009 Talphera, Inc Completed No outcome recorded
Phase 2 NCT00612534 Mar → Oct 2008 Talphera, Inc Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT06364072 May 2024 → May 2025 Cessatech A/S Completed No outcome recorded
Phase 2/3 NCT02334150 Jun 2013 → Jun 2014 dystocia Nanjing Maternity and Child Health Care Hospital Completed No outcome recorded
Phase 321 trials
Phase 3 NCT06917651 Apr 2025 → Apr 2027 expected University Hospital, Clermont-Ferrand Recruiting No outcome recorded
Phase 3 NCT06181695 May 2024 → May 2026 overdue sickle cell disease Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 3 NCT05288348 Aug 2022 → Jan 2024 Frank Guyette Completed No outcome recorded
Phase 3 NCT05196256 Jun 2022 → Jun 2023 obstetric disorder Brugmann University Hospital Unknown No outcome recorded
Phase 3 NCT04076748 Jul 2021 → Jul 2024 sickle cell disease University Hospital, Bordeaux Terminated No outcome recorded
Phase 3 NCT03639389 Jan 2019 → Mar 2022 Karolinska Institutet Completed No outcome recorded
Phase 3 NCT05576675 May 2018 → Mar 2022 Xijing Hospital Completed No outcome recorded
Phase 3 NCT02662764 Sep 2016 → Apr 2017 Talphera, Inc Completed No outcome recorded
Phase 3 NCT02662556 Mar → Jun 2016 Talphera, Inc Completed No outcome recorded
Phase 3 NCT02447848 Oct 2015 → Jun 2016 Talphera, Inc Completed No outcome recorded
Phase 429 trials
Phase 4 NCT07624006 Jan 2027 → Feb 2030 expected University Hospital, Strasbourg, France Not yet recruiting No outcome recorded
Phase 4 NCT07597564 Jun 2026 → May 2027 expected Fujian Provincial Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07026162 Jul 2025 → Feb 2026 YanYing Xiao Completed No outcome recorded
Phase 4 NCT06784999 Jan 2025 → Nov 2027 expected Indiana University Recruiting No outcome recorded
Phase 4 NCT05957653 Oct 2023 → Sep 2025 prostate cancer RenJi Hospital Unknown No outcome recorded
Phase 4 NCT06439368 Jan 2023 → Dec 2024 Yangtze River Pharmaceutical Group Co., Ltd. Unknown No outcome recorded
Phase 4 NCT04716413 Sep 2021 → Nov 2022 Montefiore Medical Center Terminated No outcome recorded
Phase 4 NCT04263909 Dec 2020 → Apr 2022 substance-related disorder Brigham and Women's Hospital Completed No outcome recorded
Phase 4 NCT04387136 Oct 2020 → Feb 2021 University of Minnesota Completed No outcome recorded
Phase 4 NCT04226495 Oct 2020 → Oct 2021 University of Nebraska Completed No outcome recorded
Phase not applicable42 trials
NCT07650812 Jul 2026 → Dec 2027 expected bowel dysfunction Beijing Tiantan Hospital Not yet recruiting No outcome recorded
NCT07651722 Jun → Sep 2026 expected paralytic ileus Tianjin First Central Hospital Recruiting No outcome recorded
NCT07089173 Aug 2025 → Jul 2026 overdue Peking University Shenzhen Hospital Recruiting No outcome recorded
NCT07401641 Jun 2025 → Jun 2026 overdue oral cavity cancer Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Recruiting No outcome recorded
NCT06990893 Jun 2025 → Oct 2026 expected Anqing Municipal Hospital Recruiting No outcome recorded
NCT06808841 Feb → May 2025 overdue Second Hospital of Shanxi Medical University Not yet recruiting No outcome recorded
NCT06015165 Sep 2024 → Jun 2025 overdue China-Japan Friendship Hospital Recruiting No outcome recorded
NCT06414018 May → Dec 2024 Tongji Hospital Completed No outcome recorded
NCT06260046 Mar 2024 → Jan 2025 overdue Seoul National University Hospital Not yet recruiting No outcome recorded
NCT06658990 Feb → Jun 2024 Northern Jiangsu People's Hospital Completed No outcome recorded
Also used as a comparator or background therapy in 191 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT06570538 Comparator Sep 2024 → May 2025 overdue Affiliated Cancer Hospital & Institute of Guangzhou Medical University Not yet recruiting No outcome recorded
Phase 0 NCT03763084 Comparator Feb 2019 → Feb 2020 delirium, paracetamol poisoning Xiangya Hospital of Central South University Unknown No outcome recorded
Phase 12 trials
Phase 1 NCT05742256 Comparator Mar 2023 → Jul 2024 Qianfoshan Hospital Unknown No outcome recorded
Phase 1 NCT04807335 Comparator Mar → Jun 2021 Cessatech A/S Completed No outcome recorded
Phase 210 trials
Phase 2 NCT07510217 Comparator Aug 2024 → Dec 2025 Tanta University Completed No outcome recorded
Phase 2 NCT06036797 Comparator Sep → Oct 2023 Maternal and Child Health Hospital of Hubei Province Unknown No outcome recorded
Phase 2 NCT05901441 Comparator Jun 2022 → May 2023 Maternal and Child Health Hospital of Hubei Province Completed No outcome recorded
Phase 2 NCT03433976 Background May 2018 → May 2020 University Hospital, Montpellier Unknown No outcome recorded
Phase 2 NCT02705872 Comparator Mar 2016 → Mar 2018 Brugmann University Hospital Withdrawn No outcome recorded
Phase 2/36 trials
Phase 2/3 NCT05508594 Comparator Sep 2022 → Oct 2023 Cessatech A/S Completed No outcome recorded
Phase 2/3 NCT05446623 Comparator Jan 2021 → Oct 2024 arthropathy Centre Hospitalier de Montauban Completed No outcome recorded
Phase 2/3 NCT04021264 Comparator Aug 2019 → Jan 2022 intestinal disorder, liver disorder, pancreas disorder University of Alberta Withdrawn No outcome recorded
Phase 2/3 NCT02700893 Comparator Mar → Aug 2016 cerebrovascular disorder Centre Hospitalier Intercommunal Creteil Completed No outcome recorded
Phase 2/3 NCT01490580 Comparator May 2012 → Aug 2016 Centre Hospitalier Intercommunal Creteil Completed No outcome recorded
Phase 315 trials
Phase 3 NCT07414706 Background Mar 2026 → Jun 2028 expected local anesthetic poisoning Centre Hospitalier Universitaire, Amiens Not yet recruiting No outcome recorded
Phase 3 NCT07166991 Comparator Feb 2026 → Sep 2028 expected University Hospital, Grenoble Recruiting No outcome recorded
Phase 3 NCT05831345 Comparator Feb 2023 → Dec 2025 overdue Brugmann University Hospital Recruiting No outcome recorded
Phase 3 NCT05072704 Comparator Feb 2022 → Feb 2023 CMC Ambroise Paré Completed No outcome recorded
Phase 3 NCT04797312 Comparator Jul 2021 → Nov 2022 local anesthetic poisoning University Hospital, Angers Unknown No outcome recorded
Phase 477 trials
Phase 4 NCT07659132 Background Jun → Sep 2026 expected urolithiasis Shiyou Wei Not yet recruiting No outcome recorded
Phase 4 NCT07660380 Comparator Jun → Jul 2026 overdue Shiyou Wei Not yet recruiting No outcome recorded
Phase 4 NCT07637968 Comparator Jun 2026 → Jan 2027 expected Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Not yet recruiting No outcome recorded
Phase 4 NCT07576517 Background Jun 2026 → Jun 2029 expected cognitive disorder Peking University First Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07334132 Background Apr 2026 → Dec 2029 expected osteoarthritis Region Örebro County Not yet recruiting No outcome recorded
Phase not applicable79 trials
NCT07702240 Comparator Jul 2026 → Mar 2028 expected biliary tract disorder Ren Da Not yet recruiting No outcome recorded
NCT07584902 Comparator Apr → Oct 2026 expected hepatobiliary disorder Gang Chen Not yet recruiting No outcome recorded
NCT07479446 Comparator Mar 2026 → Aug 2027 expected cerebellopontine angle tumor Xuanwu Hospital, Beijing Recruiting No outcome recorded
NCT07386626 Comparator Mar → Dec 2026 expected Tongji Hospital Recruiting No outcome recorded
NCT07323043 Comparator Jan → Aug 2026 overdue local anesthetic poisoning The First People's Hospital of Lianyungang Recruiting No outcome recorded

Evidence & citations 27 cited values

Every value below carries the sentence it was read from. 305 sources stand behind the page.

FieldValueCited text
Known as sufentanil “After surgery, patient-controlled intravenous analgesia will be established with dexmedetomidine (DEX 1.5 ug/ml), esketamine (ESK 0.5 mg/ml), and sufentanil (1.25 ug/ml),...” NCT07523321
288

“Postoperative patient-controlled analgesia will be established with a 100 mL mixture (containing 1.0 μg/mL sufentanil, 1.25 μg/mL dexmedetomidine, and 0.25 mg/mL esketamine in...” NCT07576517

“The parturients were randomly assigned to groups receiving either spinal sufentanil (5 µg), epidural sufentanil (20 µg), spinal fentanyl (20 µg) or epidural fentanyl (100 µg),...” PMID 31286476 Jul 2019

“Epidural block is widely used as an analgesic method during labor. During epidural anaesthesia, lipophilic opioids such as sufentanil, are often combined with local anesthetics...” NCT03395600

“The study solutions were either 0.568 mg x ml(-1) levobupivacaine (low concentration group) or 1.136 mg x ml(-1) levobupivacaine (high concentration group), with sufentanil...” PMID 20565392 Jun 2010

“The aim of this study was to compare the recovery of 2 Bispectral index (BIS)-guided anesthesia protocols combining sevoflurane-sufentanil (SS) or propofol-remifentanil (PR)...” PMID 23774117 Jan 2014

“Open-label, Prospective Study to Assess the Safety, Tolerability, Analgesic Effect and Feasibility of Intranasal Sufentanil/Ketamine in Pediatric Patients With Moderate or...” NCT06364072

Sufentanil, unlike morphine and hydromorphone, avoids the issue of active metabolites that can lead to prolonged, untoward effects, which can complicate postoperative care and...” NCT04263909

“This typically involves the intravenous (IV) administration of strong opioids such as Fentanyl or Sufentanil to manage the intense pain during the craniotomy (bone flap...” NCT07510217

“Remimazolam 6mg/kg/h was pumped intravenously for 2.5 min, Sufentanil 0.5 μg/kg and rocuronium 0.6mg/kg were injected intravenously, and endotracheal intubation was performed 3...” NCT06775366

“Postoperative analgesia was provided by patient-controlled intravenous sufentanil, supplemented by randomly assigned dexmedetomidine (1.25 μg/mL) or placebo, for up to three days.” PMID 34517840 Sep 2021

“Total intravenous anesthesia induced with sufentanil,etomidate,cisatracurium and midazolam and maintained with propofol,cisatracurium and remifentanil target controlled infusion” NCT03129009

“Patients were randomized to receive an epidural infusion of levobupivacaine 0.125% + sufentanil 0.75 μg/mL or of ropivacaine 0.2% + sufentanil 0.75 μg/mL at 5 mL/h for 48 hours.” PMID 25977992 Aug 2015

“After surgery, patient-controlled intravenous analgesia will be established with dexmedetomidine (DEX 1.5 ug/ml), esketamine (ESK 0.5 mg/ml), and sufentanil (1.25 ug/ml)” NCT07525999

“General anesthesia will be maintained with inhalation (sevoflurane) and sufentanil infusion, and muscle relaxants will be administered when considered necessary.” NCT03245346

“Patients were randomized to receive sufentanil 0.05ug/kh/h + dexmedetomidine 0.1ug/kg/h (DEX group) or sufentanil 0.05ug/kg/h + saline (control group) for 48h.” NCT03117023

“Patient-controlled analgesia is established with dexmedetomidine (1 μg/ml), esketamine (1 mg/ml), and sufentanil (1 μg/ml) in a total volume of 100 ml.” NCT06566482

“general anesthesia induction: midazolam 0.1mg/Kg, sufentanil 1ug/Kg, cisatracurium 0.15mg/Kg, and then immediatly administrate etomidate 0.2 mg/Kg” NCT02154074

“Effect of Dezocine Combined With Sufentanil on the Quality of Postoperative Recovery and Analgesic Effect in Patients Undergoing Thoracic Surgery” NCT06439368

“Optional intrathecal opioid adjuncts, with fentanyl or sufentanil, may be used to enhance analgesia according to routine clinical practice.” NCT07334132

“Patients used the Zalviso™ (sufentanil sublingual tablet system) 15 mcg to self-administer a tablet of study drug as needed for pain.” NCT02662764

“The pump is established with S-ketamine 1mg/kg, sufentanil 2microgram/kg, andondansetron16mg, diluted with normal saline to 100 ml.” NCT05299866

“Intravenous injection of 0.1ug/kg sufentanil and 0.03mg/kg midazolam for sedation and analgesia before radial artery cannulation” NCT05863455

“Remimazolam, sufentanil and rocuronium were used during induction, and remimazolam and refentanil were used during maintenance” NCT06990763

“were given sufentanil citrate 0.1-0.2 µg/kg, cisatracurium 0.2 mg/kg and propofol 1.5-2.0 mg/kg during anesthesia induction.” NCT05550714

“Patient-controlled intravenous analgesia is established with 100 μg dexmedetomidine, 50 mg esketamine, and 100 μg sufentanilNCT06859892

“all patients receive spinal anesthesia with a solution of 2 ml hyper-baric bupivacaine 0.5% (10 mg) and 3 μg of sufentanilNCT07377630

“It will consist of the following local anesthetics and adjuvants: Hypobaric Bupivacaine 0.5% 7.5 mg and Sufentanil 5 µg.” NCT06155903

Sufentanil 0.5 mg/L is used as solution for injection for epidural analgesia and used in combination with ropivacaine.” NCT02857465

“Single- and Multiple-Dose Pharmacokinetics of Sublingual Sufentanil NanoTab® PCA System (Zalviso™) in Healthy Subjects” NCT01761565

“Postoperative intravenous analgesia pump formula:Esketamine 0.2mg/kg + Sufentanil 1ug/kg+ Flurbiprofen Axetil 200mg.” NCT05229913

“In the opioid anesthetic group, intravenous sufentanil will be administrated during the organ procurement procedure.” NCT07166991

“Effect of Equivalent Dose of Alfentanil and Sufentanil Combined With Remimazolam in Complex Bronchoscopic Treatment” NCT06414018

“Rescue opioids will be given as sufentanil 5μg/hr, depending on the time of the last intraoperative administration.” NCT06015165

“Intraoperative analgesia will be administered with conventional opioid drugs such as sufentanil and remifentanil.” NCT06607029

“For all patients, the induction protocol is midazolam 0.1 mg/kg, sufentanil 0.3 μg/kg, cisatracurium 0.15 mg/kg.” NCT02147678

“Another PCIA device contained sufentanil 2 ug/kg, granisetron 12 mg diluted to 200 mL in 0.9 % normal saline.” NCT06778460

“Intra-operatively: Bupivacaine 0.5% with adrenaline Post-operatively: Ropivacaine 0.2% + sufentanil 1 ug” NCT01367418

“a formulation consisting of esketamine 50mg and sufentanil 200 μg, diluted to a total volume of 200 ml.” NCT06817239

“Anesthesia was induced by sequential intravenous injection of remimazolam, sufentanil, and rocuronium.” NCT07192549

“During the operation, both the induction and maintenance of anesthesia were achieved using sufentanil.” NCT07650812

“Both 2.5 µg sufentanil and 100 µg morphine were added to the local anaesthetic agent in both groups.” PMID 33428221 Jan 2021

Sufentanil intravenous (0.1 in 0.2 µg / kg) and propofol (5 in 10 mg / kg on 3 mn) administration” NCT02505880

“Anesthesia was induced by intravenous injection of Sufentanil 0.1 µg/kg and propofol 2 mg /kg.” NCT06367218

“All patients received 5 μ g of sufentanil 1 minute before intravenous infusion of ciprofol” NCT06172140

“Traditional general anesthetic technique utilizing sufentanil, fentanyl or remifentanil” NCT02752477

“Induction use Sufentanil 0.5\~1ug/kg, Vecuronium for Injection 0.15mg/kg and Etomidate” NCT02727712

“General anesthesia induction will be induced performed with sufentanil (0.5 μg kg-1)” NCT06199011

“Drug: Sufentanil will be injected in the subarachnoid space with a dose of 2,5μg” NCT03849508

“Patient-controlled intravenous analgesia regimen is conducted with sufentanil.” NCT03682354

“Epidural analgesia is performed with a mixture of ropivacaine and sufentanil.” NCT03012945

“sublingual sufentanil (Dsuvia) will improve postoperative pain management” NCT04716413

“5, 7 mcg of Sufentanil (Sufenta, Janssen-Pharmaceutica, amp. 5 mcg/ml)” NCT02385539

sufentanil was administered for analgesia in primary cesarean section” NCT02595333

“Anesthesia is induced and maintained with desflurane and sufentanilNCT03864276

“the PCIA pump equipped with sufentanil injection will be connected” NCT06145165

“Spinal anesthesia with bupivacaine 12.5 mg+sufentanil 5 ug” NCT03639389

Sufentanil 0.5 mcg/kg + ketamine 0.5 mg/kg as nasal spray” NCT04897750

“Individualized analgesia with sufentanil and ropivacaine” NCT02920489

Sufentanil: Fentatienil®, Angelini, Rome, Italy.” NCT01860521

Sufentanil (0.15 mg / kg intravenously (IV))” NCT02036736

“0.5 μ g / ml sufentanil+ 0.1 % ropivacaine” NCT03622047

sufentanil 0.3μg/kg (intravenous bolus)” NCT04507165

“Propofol 2 mg/kg; Sufentanil 0.2 µg/kg” NCT07414706

“mixture of bupivacaine and sufentanilNCT04755712

Sufentanil is used after surgery” NCT06658990

“0.3-0.5 μg/kg sufentanilNCT07603596

sufentanil 0.3μg/kg iv” NCT06120439

NCT02597699

NCT01721070

NCT02563821

NCT03185403

NCT02490540

NCT01490580

NCT06530563

NCT02503826

NCT01858090

NCT00859313

NCT03135795

NCT04807335

NCT02544282

NCT02868944

NCT04561375

NCT05384665

NCT02700893

NCT02794584

NCT02095366

NCT06305221

NCT04387136

NCT01261689

NCT05497492

NCT06091904

NCT07323043

NCT02085577

NCT02082236

NCT02910206

NCT07386626

NCT01505283

NCT04144933

NCT04448457

NCT00772616

NCT03598192

NCT01954368

NCT07624006

NCT02873091

NCT01086956

NCT07092384

NCT01082744

NCT03096730

NCT07651722

NCT03171610

NCT02043366

NCT03007121

NCT03901716

NCT01639729

NCT01489631

NCT02430090

NCT01248871

NCT03726268

NCT04248179

NCT02356588

NCT05670561

NCT03825198

NCT06968546

NCT01356732

NCT05307341

NCT04432428

NCT07204106

NCT02152514

NCT05901441

NCT05624424

NCT02134093

NCT03868111

NCT03152955

NCT06795594

NCT02447848

NCT06041425

NCT02334150

NCT02400879

NCT07597564

NCT02604797

NCT02705872

NCT01777100

NCT07145775

NCT03386630

NCT05742256

NCT05242081

NCT03763084

NCT02741219

NCT03036384

NCT02712528

NCT01320475

NCT02499445

NCT06990893

NCT05718544

NCT01660763

NCT07026162

NCT04048070

NCT02989597

NCT03381495

NCT05957653

NCT04446715

NCT07187765

NCT06037330

NCT05785234

NCT04797312

NCT07089173

NCT04137198

NCT03018171

NCT01608334

NCT02264834

NCT02111265

NCT07244822

NCT02213718

NCT07401641

NCT05596071

NCT06570538

NCT04177862

NCT05960942

NCT07376577

NCT06382961

NCT06260046

NCT05423951

NCT04121416

NCT04111328

NCT06784999

NCT02962830

NCT02036242

NCT00943566

NCT03470363

NCT06082856

NCT00833040

NCT07713134

NCT01235637

NCT03830086

NCT05259098

NCT03344042

NCT07018375

NCT05826327

NCT03224039

NCT02677532

NCT02053818

NCT05042817

NCT02625181

NCT05249153

NCT02205580

NCT07584902

NCT02488291

NCT01910285

NCT04443946

NCT05672212

NCT02662556

NCT00894699

NCT01025102

NCT04791059

NCT01856166

NCT01871935

NCT02831101

NCT06958393

NCT02756598

NCT04226495

NCT04396587

NCT02232347

NCT01785446

NCT02816567

NCT01490268

NCT00612534

NCT00421720

NCT06000137

NCT06036797

NCT06917651

NCT02647047

NCT05072704

NCT02710877

NCT01406678

NCT00718081

NCT06232785

NCT07702240

NCT05698407

NCT07235995

NCT01917045

NCT03685188

NCT06900205

NCT06181695

NCT07083440

NCT01710345

NCT01525537

NCT06310785

NCT00656773

NCT01012999

NCT05288348

NCT02552459

NCT05548465

NCT01759706

NCT02666794

NCT00987441

NCT05416073

NCT05576675

NCT04067648

NCT07372209

NCT05446623

NCT05750056

NCT04213781

NCT01572116

NCT02573597

NCT07660380

NCT00738192

NCT03738137

NCT04924621

NCT07637968

NCT07084753

NCT01047241

NCT05508594

NCT00437996

NCT07307495

NCT07659132

NCT01539642

NCT06808841

NCT07064408

NCT04959812

NCT04076748

NCT04464512

NCT04021264

NCT07019818

NCT00434382

NCT01539538

NCT07479446

NCT00577200

NCT03864016

Known as ARX-F01 “A Multicenter, Randomized, Placebo-Controlled Phase 2 Study to Evaluate the Clinical Efficacy, Safety, and Tolerability of ARX-F01 Sublingual Sufentanil in Patients Undergoing...” NCT00718081
1

“the ARX-F01 pain medication (Sufentanil NanoTab 15 mcg) for the treatment of post-operative pain” NCT00859313

Known as Brand name:Sufenta Brand name:SufentaNCT01572116
Known as DSUVIA “Randomized, interventional trial of Emergency Department (ED) administration of DSUVIA (sufentanil) versus standard care pain management comparing pain treatment outcomes in...” NCT05288348
1

“sublingual sufentanil (Dsuvia) will improve postoperative pain management” NCT04716413

Known as Dzuveo “including sublingual sufentanil (Dzuveo®, 30 µg), which combines opioid-like effects with a faster onset of action due to its lipophilicity.” NCT07624006
Known as IDS-NS-001 ChEMBL registry synonym — accepted as the source's own label CHEMBL658
Known as R 33800 ChEMBL registry synonym — accepted as the source's own label CHEMBL658
Known as R30730 “Sufentanil (R30730, brand name Sufenta)” NCT01917045
Known as Sufenta Sufentanil (R30730, brand name Sufenta)” NCT01917045
Known as Sufenta preservative free ChEMBL registry synonym — accepted as the source's own label CHEMBL658
Known as Sufental ChEMBL registry synonym — accepted as the source's own label CHEMBL658
Known as sufentanil (DSUVIA) sufentanil (DSUVIA)NCT05307341
Known as Sufentanil = Sufenta Sufentanil = SufentaNCT01367418
Known as Sufentanil Citrate Sufentanil Citrate injection, specification: 50 ug/ml, 1 ml; Avoid light seal; Yichang humanwell pharmaceutical co., LTD.” NCT06530563
3

“Drug: Sufentanil CitrateNCT03685188

“Drug: Sufentanil citrateNCT07651722

NCT05831345

Known as Sufentanil citrate cii ChEMBL registry synonym — accepted as the source's own label CHEMBL658
Known as sufentanil injection “Drug: Sufentanil InjectionNCT04067648
1

sufentanil injectionNCT06530563

Known as Sufentanil NanoTab “the ARX-F01 pain medication (Sufentanil NanoTab 15 mcg) for the treatment of post-operative pain” NCT00859313
1

Sufentanil NanoTab 20 mcg as needed every 60 minutes for 12 hours” NCT01710345

Known as Sufentanil, Sufenta, (R-30730) Sufentanil, Sufenta, (R-30730)NCT01406678
Known as Sufentanil: Fentatienil, Angelini, Rome, Italy. “Sufentanil: Fentatienil®, Angelini, Rome, Italy.” NCT01860521
Known as Sufentanilo ChEMBL registry synonym — accepted as the source's own label CHEMBL658
Known as sufentanyl “Midazolam 0.03 mg/kg injection vein,Sufentanyl 0.5\~1 μg/kg, target controlled infusion of etomidate or propofol,after the consciousness of patients is lost, rocuronium...” NCT02644980
12

“A combined spinal epidural anesthesia with spinal administration of 50 mg hyperbaric prilocaine 2% (Tachipri, Nordic Pharma) + 2,5mcg sufentanyl (5 mcg/ml) (Janssens-cilag)” NCT03219086

“Midazolam 0.05 mg/kg、Propofol 1.0 mg/kg、Sufentanyl 3μg/kg、Victracurium 0.1 mg/kg sequential intravenous injection” NCT02123355

“The patient will receive the intravenous opioid analgesic sufentanyl 0.2 mcg/kg over a period of 30 seconds.” NCT07456111

“spinal anesthesia with 10 mg hyperbaric Bupivacaïne 0,5% + 2,5 µ Sufentanyl + 100 µ of intrathecal Morphine” NCT02711072

“propofol 2mg kg-1, sufentanyl 0.3-0.5 μ g kg-1, rocuronium” NCT06493396

“using sufentanyl 5mg intravenously during the surgery” NCT05815056

NCT07406555

NCT01516268

NCT05196256

NCT02923128

NCT05731973

NCT03677323

Known as Zalviso “Patients used the Zalviso™ (sufentanil sublingual tablet system) 15 mcg to self-administer a tablet of study drug as needed for pain.” NCT02662764
Known as Zalviso (sufentanil sublingual tablet system) 15 mcg “Zalviso™ (sufentanil sublingual tablet system) 15 mcg” NCT02662764
Action Activate “Mu opioid receptor agonist” CHEMBL658
1

“a pure μ receptor agonist” NCT03685188

Modality Other / unclassified “Sufentanil (medium/long acting opioid)” NCT02053818