Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer

Phase 1 Unknown 159 enrolled Qianfoshan Hospital

RandomizedParallel-groupSingle-blindTreatment

Summary

In this study, the effect of oxycodone combined with ultrasound-guided paravertebral nerve block on the postoperative analgesic effect of thoracoscopic lung cancer was investigated, and the effect and reasonable dose of oxycodone were explored, which provided a reference for the clinical multimodal analgesia after thoracoscopic lung cancer surgery.

Timeline

Start: 2023-03-01
Primary completion: 2024-07-31
Completion: 2024-12-31

Publications

Wang Y, Wu G, Liu Z, Wei X, Feng H, Su J, Shi P. Effect of oxycodone combined with ultrasound-guided thoracic paravertebral nerve block on postoperative analgesia in patients with lung cancer undergoing thoracoscopic surgery: protocol for a randomised controlled study. BMJ Open. 2023 Oct 16;13(10):e074416. doi: 10.1136/bmjopen-2023-074416.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oxycodone	Other / unclassified	1 mg/kg	Intravenous
Subject	Oxycodone	Other / unclassified	1.5 mg/kg	Intravenous
Comparator	Sufentanil	Other / unclassified	2 ug/kg	Intravenous
Background	Flurbiprofen	Small molecule	50 mg	—
Background	Ondansetron	Other / unclassified	16 mg	—

Indications

No indication recorded.