Drugs / Ondansetron
last change 3 days ago re-read 2 minutes ago

Ondansetron

Other / unclassified targets HTR3A via inhibition

Developed for
gastroenteritis · alcohol dependence · chemotherapy-induced toxicity · diarrheal disease · hypotensive disorder · irritable bowel syndrome · obsessive-compulsive disorder · schizophrenia
+43 more · substance-related disorder · alcohol abuse · alcohol-related disorders · benign shuddering attacks · cancer · cholecystitis · cocaine dependence · drug dependence · hyperemesis gravidarum · intracranial hypotension · neuropathy, painful · poisoning · substance withdrawal syndrome · AChR+ myasthenia gravis · acute lung injury · acute respiratory distress syndrome · atrial fibrillation · childhood neoplasm · diabetes mellitus · dyspepsia · gastritis · gastroesophageal reflux disease · gastroparesis · headache disorder · juvenile idiopathic arthritis · methamphetamine dependence · neonatal abstinence syndrome · nicotine dependence · pain agnosia · radiation-induced disorder · thyroid cancer · traumatic brain injury · benign paroxysmal positional vertigo · bipolar disorder · cannabis dependence · cyclic vomiting syndrome · heart failure · infectious disease with sepsis · pancreas disorder · schizoaffective disorder · schizophreniform disorder · syncope, familial vasovagal · Tourette syndrome
Investigated by
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · Tanta University · Merck Sharp & Dohme LLC · National Institute on Drug Abuse (NIDA) · University of Virginia · Algorithme Pharma Inc
+199 more · Par Pharmaceutical, Inc. · Stanford University · Bankole Johnson · Forest Laboratories · GlaxoSmithKline · Mylan Pharmaceuticals Inc · National Cancer Institute (NCI) · Peking Union Medical College Hospital · The Hospital for Sick Children · University of British Columbia · University of Colorado, Denver · Washington University School of Medicine · Aga Khan University · Ain Shams University · Assiut University · Bill and Melinda Gates Foundation · Dr. Stephen Freedman · Hamad Medical Corporation · Icahn School of Medicine at Mount Sinai · Institute of Neuroscience, Florence, Italy · Khon Kaen University · Mayo Clinic · Minia University · Mongi Slim Hospital · NHS Lothian · National Institute for Health Research, United Kingdom · RedHill Biopharma Limited · Sandoz · Sohag University · St. Justine's Hospital · Takeda · Teva Pharmaceuticals USA · Thrasher Research Fund · University of Calgary · University of Manitoba · University of Maryland, Baltimore · University of Montreal · University of Nottingham · University of Texas · Yonsei University · Aarhus University Hospital · Acacia Pharma Ltd · Adial Pharmaceuticals · Adwia Pharma, Egypt · Agenzia Italiana del Farmaco · Air Liquide · Alberta Children's Hospital · Alberta Children's Hospital Research Institute · Alliance for Clinical Trials in Oncology · American Heart Association · Amgen · Ann & Robert H Lurie Children's Hospital of Chicago · Aquestive Therapeutics · Asan Medical Center · Assistance Publique - Hôpitaux de Paris · Australasian Leukaemia and Lymphoma Group · Barnsley Hospital NHS Foundation Trust · Barts & The London NHS Trust · Bispebjerg Hospital · Blood and Marrow Transplant Group of Georgia · Bnai Zion Medical Center · Bonsucesso Federal Hospital · Brest, Norman A., M.D. · Brown University · CHU de Quebec-Universite Laval · Canadian Institutes of Health Research (CIHR) · Catholic University of the Sacred Heart · Centre Hospitalier Universitaire Dijon · Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal · Chief Scientist Office of the Scottish Government · Children's Hospital Research Institute of Manitoba · Chinese Academy of Medical Sciences · Chongqing University Cancer Hospital · Chugai Pharma UK Limited · all 205 on the full record

Regulatory milestones approvals, filings & regulatory actions · 10 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (9) US (FDA) ZOFRAN 1993-02-02 – 2005-03-25 fda.gov
Approved US (FDA) ZOFRAN 1991-01-04 fda.gov

Trials 187 · started per year

today
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 04 trials
Phase 0 NCT05819619 Jul 2023 → Apr 2024 Hackensack Meridian Health Terminated No outcome recorded
Phase 0 NCT04891484 Apr 2021 → Apr 2022 nephrolithiasis Mansoura University Completed No outcome recorded
Phase 0 NCT03125811 Jul 2017 → Mar 2023 Texas Tech University Health Sciences Center, El Paso Completed No outcome recorded
Phase 0 NCT01851993 Jun 2013 → Sep 2014 McGill University Completed No outcome recorded
Phase 128 trials
Phase 1 NCT07310563 Dec 2024 → May 2025 obesity disorder Amgen Completed No outcome recorded
Phase 1 NCT06297499 Aug 2024 → Aug 2025 overdue Wayne State University Recruiting No outcome recorded
Phase 1 NCT05124067 Oct 2021 → Jan 2022 delirium Tanta University Completed No outcome recorded
Phase 1 NCT03809234 May 2019 → Nov 2020 neuropathy, painful Washington University School of Medicine Terminated No outcome recorded
Phase 1 NCT03583489 Jul → Aug 2018 Acacia Pharma Ltd Completed No outcome recorded
Phase 1 NCT02614586 Dec 2015 → Apr 2016 schizophrenia Takeda Terminated No outcome recorded
Phase 1 NCT02460341 Aug 2015 → Feb 2017 Icahn School of Medicine at Mount Sinai Completed No outcome recorded
Phase 1 NCT02473887 Sep 2014 → Jan 2015 gastroenteritis Hamad Medical Corporation Completed No outcome recorded
Phase 1 NCT01815125 Mar 2013 → Feb 2014 traumatic brain injury St. Justine's Hospital Completed No outcome recorded
Phase 1 NCT01572012 Feb 2012 → Nov 2013 Halozyme Therapeutics Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT04603066 Jan 2021 → Oct 2023 neuropathy, painful Washington University School of Medicine Completed No outcome recorded
Phase 1/2 NCT01217190 Sep 2008 chemotherapy-induced toxicity MonoSol Rx Completed No outcome recorded
Phase 233 trials
Phase 2 NCT07381634 Mar → Dec 2026 expected hepatocellular carcinoma First Affiliated Hospital of Wenzhou Medical University Not yet recruiting No outcome recorded
Phase 2 NCT04226170 Nov 2023 → Apr 2025 AChR+ myasthenia gravis DAS-MG, Inc Terminated No outcome recorded
Phase 2 NCT05378113 May → Aug 2023 Emory University Terminated No outcome recorded
Phase 2 NCT05342818 Apr → Jul 2022 gastroparesis Tanta University Completed No outcome recorded
Phase 2 NCT05202574 Sep 2021 → Feb 2022 intracranial hypotension Minia University Unknown No outcome recorded
Phase 2 NCT04557189 Oct 2020 → Mar 2022 Takeda Completed No outcome recorded
Phase 2 NCT06289335 Aug 2020 → Sep 2021 Hospital Central "Dr. Ignacio Morones Prieto" Completed No outcome recorded
Phase 2 NCT04468685 Jul → Dec 2020 cholecystitis National Hepatology & Tropical Medicine Research Institute Completed No outcome recorded
Phase 2 NCT03865290 Apr 2019 → Mar 2028 expected diabetes mellitus, dyspepsia Mayo Clinic Recruiting No outcome recorded
Phase 2 NCT03785691 Mar 2019 → Jul 2022 hyperemesis gravidarum Nordsjaellands Hospital Terminated No outcome recorded
Phase 2/34 trials
Phase 2/3 NCT07588217 Oct 2026 → Oct 2028 expected acute lung injury, acute respiratory distress syndrome Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal Not yet recruiting No outcome recorded
Phase 2/3 NCT03052361 Jul 2017 → Sep 2020 gastroenteritis St. Justine's Hospital Terminated No outcome recorded
Phase 2/3 NCT01591291 Jun 2012 → Dec 2017 alcohol dependence University of Virginia Withdrawn No outcome recorded
Phase 2/3 NCT01414777 Nov 2009 → Jun 2011 hypotensive disorder, pregnancy disorder University of Virginia Completed No outcome recorded
Phase 327 trials
Phase 3 NCT05876585 Jun 2025 overdue gastroenteritis Genuine Research Center, Egypt Not yet recruiting No outcome recorded
Phase 3 NCT06282211 Feb → Mar 2024 The First Affiliated Hospital of Xinxiang Medical College Unknown No outcome recorded
Phase 3 NCT06208917 Jul 2023 → Jul 2026 overdue childhood neoplasm Yizhuo Zhang Recruiting No outcome recorded
Phase 3 NCT05872893 Jun 2023 → Jan 2025 childhood malignant neoplasm Immune Oncology Research Institute Completed No outcome recorded
Phase 3 NCT05620641 Oct 2022 → Feb 2025 morbid obesity Tanta University Completed No outcome recorded
Phase 3 NCT04703088 Jun → Aug 2021 hypotensive disorder Laval University Unknown No outcome recorded
Phase 3 NCT05087615 Mar → Aug 2021 Shahid Beheshti University of Medical Sciences Completed No outcome recorded
Phase 3 NCT04101227 Feb 2020 → Feb 2022 alcohol-related disorders Adial Pharmaceuticals Completed No outcome recorded
Phase 3 NCT03817970 Nov 2019 → Sep 2027 expected cisplatin toxicity University of Colorado, Denver Active not recruiting No outcome recorded
Phase 3 NCT03851835 Sep 2019 → Jun 2024 diarrheal disease, gastroenteritis, viral infectious disease University of Calgary Completed No outcome recorded
Phase 443 trials
Phase 4 NCT07681076 Aug → Nov 2026 expected Karuna Therapeutics, Inc. Not yet recruiting No outcome recorded
Phase 4 NCT07638527 Jul 2026 → Feb 2027 expected Faisalabad Medical University Not yet recruiting No outcome recorded
Phase 4 NCT07336680 Jan → May 2026 overdue Peking Union Medical College Hospital Not yet recruiting No outcome recorded
Phase 4 NCT06632184 Dec 2025 → Mar 2026 overdue Mexican Social Security Institute Active not recruiting No outcome recorded
Phase 4 NCT07264738 Jul → Sep 2025 overdue Peking Union Medical College Hospital Active not recruiting No outcome recorded
Phase 4 NCT05844501 Apr 2025 → Dec 2027 expected atrial fibrillation Indiana University Recruiting No outcome recorded
Phase 4 NCT07217600 Mar 2025 → Mar 2026 overdue childhood malignant neoplasm, radiation-induced disorder Chongqing University Cancer Hospital Recruiting No outcome recorded
Phase 4 NCT06747975 Jan 2025 → Jan 2026 overdue Assiut University Not yet recruiting No outcome recorded
Phase 4 NCT06729307 Jan 2025 → Jan 2026 overdue Peking Union Medical College Hospital Not yet recruiting No outcome recorded
Phase 4 NCT06704139 Dec 2024 → Dec 2026 expected Assiut University Not yet recruiting No outcome recorded
Phase not applicable46 trials
NCT07632144 Jun → Jul 2026 overdue Mongi Slim Hospital Not yet recruiting No outcome recorded
NCT07511491 Apr → Aug 2026 overdue Tanta University Recruiting No outcome recorded
NCT07489742 Mar → Sep 2026 expected Tanta University Recruiting No outcome recorded
NCT07377903 Feb → Jul 2026 overdue Sohag University Not yet recruiting No outcome recorded
NCT06898268 Jul → Dec 2024 gastroesophageal reflux disease Muhammad Aamir Latif Completed No outcome recorded
NCT06423820 May 2024 → Jan 2025 strabismus Tanta University Completed No outcome recorded
NCT06423807 May → Sep 2024 benign shuddering attacks Tanta University Completed No outcome recorded
NCT06371014 May → Dec 2024 Shanghai Children's Medical Center Unknown No outcome recorded
NCT06300346 Mar → Aug 2024 Sohag University Unknown No outcome recorded
NCT06254131 Feb → Oct 2024 Tanta University Completed No outcome recorded
Also used as a comparator or background therapy in 267 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 05 trials
Phase 0 NCT07662200 Comparator Aug 2026 → Aug 2027 expected malignant germ cell tumor Ottawa Hospital Research Institute Not yet recruiting No outcome recorded
Phase 0 NCT04682743 Comparator Jan 2021 → Jan 2022 Cairo University Completed No outcome recorded
Phase 0 NCT03593811 Comparator Aug 2018 → Apr 2021 Vanderbilt University Medical Center Completed No outcome recorded
Phase 0 NCT03475693 Background Sep 2017 → Nov 2019 traumatic encephalopathy Corewell Health South Completed No outcome recorded
Phase 0 NCT00314743 Background Oct 2005 → Dec 2008 Washington University School of Medicine Completed No outcome recorded
Phase 115 trials
Phase 1 NCT07697625 Background Jul → Sep 2026 expected Merck Sharp & Dohme LLC Not yet recruiting No outcome recorded
Phase 1 NCT07603596 Background May 2026 → Apr 2028 expected delirium, digestive system neoplasm Qianfoshan Hospital Not yet recruiting No outcome recorded
Phase 1 NCT07201883 Comparator Aug 2025 → Feb 2026 overdue Makassed General Hospital Active not recruiting No outcome recorded
Phase 1 NCT05742256 Background Mar 2023 → Jul 2024 Qianfoshan Hospital Unknown No outcome recorded
Phase 1 NCT05035407 Background Mar 2022 → Jul 2025 National Cancer Institute (NCI) Terminated No outcome recorded
Phase 1/25 trials
Phase 1/2 NCT07706348 Comparator Jun 2026 → Jul 2027 expected Assiut University Recruiting No outcome recorded
Phase 1/2 NCT05402553 Comparator Apr 2022 → Jun 2023 infectious disease with sepsis Noha Mansour Unknown No outcome recorded
Phase 1/2 NCT04209595 Background Apr 2020 → Aug 2021 small cell lung carcinoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 1/2 NCT02858310 Background Jan 2017 → Jul 2025 cervical intraepithelial neoplasia, human papilloma virus infection, in situ carcinoma, vulvar neoplasm National Cancer Institute (NCI) Completed No outcome recorded
Phase 1/2 NCT01801475 Comparator Jan → May 2013 Stanford University Completed No outcome recorded
Phase 248 trials
Phase 2 NCT07455955 Background Mar 2026 → Jun 2027 expected breast cancer Chinese University of Hong Kong Recruiting No outcome recorded
Phase 2 NCT07668700 Background Dec 2025 → Jun 2026 Hameed Latif Hospital, Lahore Completed No outcome recorded
Phase 2 NCT07246070 Background Dec 2025 → Aug 2026 overdue chemotherapy-induced toxicity Aiping Zhou Not yet recruiting No outcome recorded
Phase 2 NCT06904235 Comparator Jul 2025 → Oct 2027 expected chemotherapy-induced toxicity Helsinn Healthcare SA Recruiting No outcome recorded
Phase 2 NCT06475846 Comparator Jun → Oct 2024 Fujian Shengdi Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2/37 trials
Phase 2/3 NCT06727201 Comparator Jan 2025 → Dec 2026 expected Assiut University Not yet recruiting No outcome recorded
Phase 2/3 NCT06382012 Comparator Nov 2024 → Mar 2027 expected Montefiore Medical Center Recruiting No outcome recorded
Phase 2/3 NCT06390787 Comparator Jan → Apr 2024 University of Baghdad Completed No outcome recorded
Phase 2/3 NCT05418244 Comparator Apr 2022 → Jun 2026 overdue State University of New York at Buffalo Recruiting No outcome recorded
Phase 2/3 NCT03367988 Background Dec 2018 → Jan 2023 drug dependence University of South Florida Unknown No outcome recorded
Phase 354 trials
Phase 3 NCT07124195 Background Aug 2025 → Oct 2026 expected cancer, chemotherapy-induced toxicity The First Affiliated Hospital of Xinxiang Medical College Not yet recruiting No outcome recorded
Phase 3 NCT06861010 Comparator Mar 2025 → Dec 2026 expected pancreas disorder Tanta University Recruiting No outcome recorded
Phase 3 NCT05657925 Comparator Dec 2024 → Dec 2026 expected syncope, familial vasovagal University of Calgary Not yet recruiting No outcome recorded
Phase 3 NCT06007586 Background May 2024 → Jun 2025 cervical cancer, endometrial cancer, fallopian tube cancer, ovarian cancer Sichuan Cancer Hospital and Research Institute Completed No outcome recorded
Phase 3 NCT04606264 Comparator May 2023 → Mar 2025 Jennifer Holder-Murray Completed No outcome recorded
Phase 471 trials
Phase 4 NCT07639723 Background Jul 2026 → Jul 2027 expected Endeavor Health Not yet recruiting No outcome recorded
Phase 4 NCT07088601 Comparator Aug → Dec 2025 overdue benign shuddering attacks Cairo University Not yet recruiting No outcome recorded
Phase 4 NCT06886230 Comparator Mar → Jun 2025 Hafiz Muhammad Hamza Completed No outcome recorded
Phase 4 NCT05956899 Comparator Jun 2023 → Mar 2024 idiopathic scoliosis University of Malaya Completed No outcome recorded
Phase 4 NCT05692245 Comparator Mar 2023 → Apr 2024 Beth Israel Deaconess Medical Center Completed No outcome recorded
Phase not applicable62 trials
NCT07558226 Comparator May 2026 → Nov 2027 expected Fundacio Puigvert Recruiting No outcome recorded
NCT05784350 Comparator Aug 2025 → May 2028 expected Meir Medical Center Not yet recruiting No outcome recorded
NCT07084753 Comparator Jul → Sep 2025 overdue obesity disorder IVO JURISIC Not yet recruiting No outcome recorded
NCT07037654 Comparator Jun 2025 → Jul 2026 overdue Suez Canal University Active not recruiting No outcome recorded
NCT06850740 Comparator Mar → Jun 2025 overdue Suez Canal University Enrolling by invitation No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2007-06-26 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Approval Of Ondansetron Hcl Tablets And Ondansetron Orally Disintegrating Tablets USP tevapharm.com
2006-02-26 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Tentative Approval of Ondansetron Injection USP tevapharm.com

Evidence & citations 43 cited values

Every value below carries the sentence it was read from. 456 sources stand behind the page.

FieldValueCited text
Known as ondansetron “METHODS: Women scheduled for elective cesarean delivery were randomized to one of three groups: placebo (placebo plus placebo); metoclopramide (metoclopramide 10 mg plus...” PMID 23635626 Mar 2013
437

“5HT3 (5-Hydroxytryptamine 3) antagonists (ondansetron, granisetron or tropisetron) used as the local institutional standard of care will be permitted, although the preferential...” NCT01843868

“Comparing the Effects of Ondansetron Versus Dexamethasone on the Incidence of Post-dural Puncture Headache (PDPH) , Nausea and Vomiting After Spinal Anaesthesia of Parturients...” NCT05202574

“Placebo, given orally Ranitide 50 mg, IV, before chemotherapy (D1) Ondansetron 8 mg, IV, before chemotherapy (D1) Dexamethasone 10 mg, IV, before chemotherapy (D1)...” NCT01052844

“30 minutes prior to emergence 0.2 μg/kg total body weight Sufentanil IV and 1 gram of paracetamol IV (if 6hrs since preoperative medicine) and 4 mg ondansetron IV (PONV...” NCT04248179

“Anesthesia will be maintained with Sevoflurane, Magnesium, Lidocaine, Ketamine, Decadron, Ondansetron, and Ketorolac at a concentration range/dose(s) based on the clinical need...” NCT03367988

“Day 1: Aprepitant 125mg QD (once daily); Ondansetron 8mg BD (twice daily); Dexamethasone 12mg QD (Aprepitant, Ondansetron and Dexamethasone to be take 60 minutes before...” NCT07455955

“Granisetron Transdermal Delivery System (GTDS) efficacy compared with the ondansetron efficacy with regard to Complete Response (CR) of Chemotherapy Induced Nausea and Vomiting (CINV).” NCT01659775

“Pramipexole group: Consenting individuals meeting accession criteria will start pramipexole 2.0mg daily dose (1.0mg twice a day) with ondansetron 16mg daily dose (8mg twice a day).” NCT03642964

“Patients will receive ondansetron (0.1 mg / kg dose of 4mg cap) associated with dexamethasone (0.15 mg / kg dose of 5mg ceiling) or dexamethasone (0.15 mg / kg) or placebo” NCT01297010

“Comparison Between Propofol, Ondansetron and Pregabalin for Control of Emetic Attacks During Caesarean Delivery With Spinal Anesthesia: Randomized Clinical Trial” NCT06300346

“To prevent postoperative nausea and vomiting (PONV), patients receive dexamethasone (8 mg), ondansetron (4 mg), and metoclopramide (10 mg) intraoperatively.” NCT07084753

“Hydration is reduced to 1 hour and 40 minutes and Akynzeo is administered as an oral drug instead of Ondansetron being given as an IV before chemotherapy.” NCT04362449

Ondansetron (Ondansetron Accord 2mg/ml, 2 ml solution, Accord Healthcare Limited, Great Britain) in a dose of 4 mg will be administered intravenously” NCT06609993

“In attempt to prevent hypotension after spinal anesthesia induction, Ondansetron, a serotonin receptor antagonist, has been used effectively” NCT05784350

“5-HT3-antagonists, including ondansetron, are commonly used as anti-emetics to prevent and treat chemotherapy-induced vomiting and nausea” NCT07706348

“With Intravenous Antiemetic Drugs Dexamethasone and Ondansetron and Incidence of Post-operative Nausea Vomiting for Inner Ear Surgery” NCT02724033

“An anti-emetic (e.g., IV ondansetron \[0.25 mg/kg, 16 mg maximum\] or equivalent) will be given as premedication for 131I-omburtamab” NCT04743661

“Randomized to either the control (pyridostigmine+ placebo) or the test group (pyridostigmine + ondansetron) and treated for 6 weeks.” NCT04226170

“The pump is established with S-ketamine 1mg/kg, sufentanil 2microgram/kg, andondansetron16mg, diluted with normal saline to 100 ml.” NCT05299866

“dexamethasone 12 mg iv, ondansetron 8 mg iv before chemotherapy aprepitant 80 mg orally D2-4, dexamethasone 8 mg/day orally D2-4” NCT03876938

“Local infiltration with bupivacaine and Piritramide and Paracetamol as postoperative analgesic, and ondansetron as required” NCT00547989

“Test group 1 (OCA group):oxycodone 1mg/kg + flurbiprofen 50mg + ondansetron 16mg + 0.9% normal saline diluted to 100ml” NCT05742256

“The patient will receive oral placebo 2 h before surgery and ondansetron 8mg intravenous at the end of the surgery” NCT03202459

“Pre-operatively, all patients will receive Ondansetron 4 mg IV, and metoclopramide 10 mg intravenously (IV).” NCT06343753

“rescue intravenous antiemetic medication using 4 mg of ondansetron will be administered by anaesthesiologist” NCT04500249

“standard care which includes ketorolac, bupivacaine, fentanyl, ondansetron, dexamethasone, sevoflurane” NCT01868425

“Participants received droperidol (0.625 or 1.25 mg) or ondansetron 4 mg during general anaesthesia.” PMID 29746373 Dec 2018

“Patients receive concurrent aprepitant 125mg, dexamethasone 12mg, and ondansetron 8mg p.o. on day1.” NCT03572829

“intravenous premedication (midazolam 2 mg and 4mg ondansetron) was administered to all patients” NCT04365686

“During surgery, 0.5mcg/kg of dexmedetomidine and 0.1mg/kg ondansetron will be given.” NCT03467750

ondansetron (Zofran) tablets combined with a medicine called dexamethasone given IV” NCT00781768

“Pre-treatment analgesia (combination of ondansetron, ketorolac, and hydromorphone)” NCT01993238

“Single oral dose of 8 mg of ondansetron pulsatile-release formulation 1 (Ond-PR1)” NCT01290276

ondansetron 4mg IV, sugammadex 2mg/kg or 4 mg/kg dose depending on twitch” NCT03448068

“the patients will be given 4mg dexamethasone and or 4mg ondansetron IV.” NCT02288923

“either ondansetron (if receiving placebo inhalation) or normal saline)” NCT00285051

“intravenous ondansetron 8 mg, and intravenous dexamethasone 12 mg” NCT06007586

Ondansetron is a medication used to prevent nausea or vomiting.” NCT07697625

Ondansetron Injection (administered on Day 1, 8 mg, once daily)” NCT07124195

“RHB-102 (BEKINDA) (Ondansetron 24 mg Bimodal Release Tablets)” NCT02246439

Ondansetron 8mg IV, D1-5 30 minutes before chemotherapy” NCT05244577

“BEKINDA (Ondansetron 12 mg Bimodal Release Tablets)” NCT02757105

“Dexketoprofen trometamol, Ondansetron or Droperidol” NCT05172739

“Dexamethasone 4mg and Ondansetron 4mg intravenously” NCT01511627

“Ketamine 0.3 mg/kg along with ondansetron 4 mg IV” NCT02735343

Ondansetron 16mg orally pre-chemotherapy on day 1” NCT04075955

ondansetron hydrochloride(8mg, i.v. day 1-day 3)” NCT04536558

“along with Ondansetron 4mg or Droperidol 0.625mg” NCT04894864

“then ondansetron 8 mg IV + esketamine 0.2 mg/kg” NCT07603596

“intravenous administration of 8 mg ondansetronNCT01819857

Ondansetron: 8-16 mg d1 intravenous or oral” NCT04437017

“and ondansetron 4mg. Fentanyl will be given” NCT01566838

ondansetron 8 mg IV x1. Post-operatively” NCT03330119

“we will give them 4 mg of ondansetronNCT03862391

“8 mg ondansetron IV in 20 mL saline” NCT06289335

“IV ondansetron 8 mg on Day 1” NCT03831633

Ondansetron: 4-8mg IV” NCT07558226

“4 mg OndansetronNCT07568938

Ondansetron 4 mg” NCT06625632

OndansetronNCT02648490

NCT02460341

NCT02460055

NCT00108095

NCT04654429

NCT00905190

NCT00711555

NCT03134612

NCT02803788

NCT00818259

NCT05872893

NCT04576390

NCT07632144

NCT06208917

NCT05956899

NCT06810882

NCT03851835

NCT00654277

NCT02601027

NCT05087615

NCT00080444

NCT00027079

NCT01121042

NCT06175806

NCT01594749

NCT01395901

NCT03262038

NCT00659685

NCT06475846

NCT01393288

NCT05755737

NCT01640340

NCT03023462

NCT04294992

NCT00699894

NCT00659945

NCT04891484

NCT03555188

NCT02862873

NCT00001337

NCT00199329

NCT00793663

NCT05006638

NCT07511491

NCT01851993

NCT01691690

NCT07668700

NCT01165866

NCT02760069

NCT01477242

NCT00946387

NCT07246070

NCT07681076

NCT02382146

NCT00653458

NCT05076461

NCT02354703

NCT06254131

NCT01536392

NCT00382642

NCT01572012

NCT05342818

NCT00018850

NCT02006056

NCT01111851

NCT03152955

NCT01661335

NCT01536691

NCT00619359

NCT01591291

NCT06371014

NCT04191694

NCT01414777

NCT00655642

NCT01275248

NCT07201883

NCT02928601

NCT05657925

NCT06282211

NCT06444737

NCT01449188

NCT01636947

NCT00343863

NCT03435692

NCT02953210

NCT02386059

NCT03973411

NCT01913990

NCT06795594

NCT04209595

NCT01837394

NCT03583489

NCT05844501

NCT00005994

NCT06390787

NCT04144933

NCT04870541

NCT03435003

NCT01912807

NCT02194192

NCT05317611

NCT04557189

NCT06904235

NCT07638527

NCT00169572

NCT01450826

NCT03653520

NCT00324467

NCT06428084

NCT03530007

NCT02901054

NCT00104403

NCT04785118

NCT00871910

NCT00651755

NCT01007500

NCT02106494

NCT04603066

NCT00437229

NCT05402553

NCT02296333

NCT07377903

NCT03833999

NCT00981487

NCT03478605

NCT06080880

NCT02830906

NCT00954941

NCT01006707

NCT00006205

NCT04606264

NCT05137288

NCT00033085

NCT05265507

NCT03931863

NCT00757822

NCT00090155

NCT07264738

NCT00599573

NCT01352130

NCT01668069

NCT03125811

NCT00795769

NCT01031498

NCT02959840

NCT00090207

NCT05819619

NCT05124067

NCT03297021

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NCT00090246

NCT01669213

NCT03022240

NCT05881486

NCT01474915

NCT00003817

NCT00934180

NCT07310563

NCT01220167

NCT02991456

NCT03182179

NCT00971399

NCT05583214

NCT01870635

NCT01870648

NCT03056482

NCT07381634

NCT00588835

NCT00768508

NCT02473887

NCT00429832

NCT00006348

NCT04140058

NCT03035942

NCT01841606

NCT01543945

NCT07588217

NCT06729307

NCT00387556

NCT00248547

NCT06927817

NCT04150614

NCT00796497

NCT04169828

NCT02541019

NCT04613726

NCT02327923

NCT03865290

NCT03239210

NCT00970905

NCT00678457

NCT05514483

NCT07639723

NCT00624208

NCT02987985

NCT03075163

NCT05418244

NCT06423820

NCT03859102

NCT04167813

NCT00601172

NCT06423807

NCT00609765

NCT05065567

NCT02793843

NCT06632184

NCT04682743

NCT03606369

NCT03237611

NCT02985840

NCT07334223

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NCT04703088

NCT02456662

NCT06898268

NCT01169805

NCT02116530

NCT00738621

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NCT03052361

NCT00659074

NCT03629522

NCT01815125

NCT00649532

NCT00929955

NCT02468323

NCT04745273

NCT00695864

NCT00825071

NCT01859715

NCT00649363

NCT07489742

NCT05221151

NCT00967499

NCT03079219

NCT00000443

NCT01113164

NCT03141645

NCT04508400

NCT03603119

NCT02021851

NCT06382012

NCT03421860

NCT01965704

NCT02519842

NCT00092183

NCT00648804

NCT00745004

NCT06930456

NCT06861010

NCT02441894

NCT04318847

NCT00641797

NCT02618343

NCT06747975

NCT02858310

NCT00137202

NCT04983498

NCT02966041

NCT00000289

NCT06656299

NCT03785691

NCT00648583

NCT04509258

NCT02913768

NCT04101227

NCT06886230

NCT01801475

NCT01759706

NCT01432977

NCT00891761

NCT06297499

NCT00366834

NCT01434017

NCT03117894

NCT01896440

NCT05035407

NCT01679093

NCT05378113

NCT03817970

NCT00642512

NCT02883192

NCT02234466

NCT02657031

NCT01549652

NCT02625181

NCT00918190

NCT04764344

NCT04503668

NCT01952626

NCT01050270

NCT07088601

NCT00314743

NCT02143531

NCT00016380

NCT00819039

NCT01303536

NCT02732015

NCT01602029

NCT05475873

NCT00947128

NCT06704139

NCT00020657

NCT01952886

NCT05692245

NCT07087925

NCT00778011

NCT05346731

NCT01370408

NCT01507194

NCT00499668

NCT02658721

NCT01876290

NCT01254877

NCT00674713

NCT05098067

NCT06437236

NCT06241547

NCT05590936

NCT04499274

NCT00539721

NCT00689572

NCT01857232

NCT00120744

NCT00734929

NCT03593811

NCT01217190

NCT03041948

NCT00149734

NCT01510379

NCT05876585

NCT03041935

NCT03685032

NCT07662200

NCT00934921

NCT07068230

NCT01067677

NCT02619201

NCT04817189

NCT02026778

NCT01697579

NCT03578081

NCT06697782

NCT01362530

NCT03017222

NCT06017167

NCT04468685

NCT03747341

NCT00231777

NCT07037654

NCT00183222

NCT07336680

NCT05620641

NCT03503292

NCT00691275

NCT00878228

NCT00040053

NCT03809234

NCT01257672

NCT02614586

NCT06727201

NCT00337727

NCT03219710

NCT00147355

NCT06153602

NCT02408146

NCT01739985

NCT02082678

NCT06850740

NCT05127876

NCT01442376

NCT02085577

NCT07217600

NCT00590317

NCT02979548

NCT02028910

NCT05439798

NCT05439772

Known as A04AA01 ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as AD04 AD04 (ondansetron)” NCT04101227
Known as BEKINDA “Randomized, Placebo-Controlled, Phase 3 Trial of RHB-102 (BEKINDA) (Ondansetron 24 mg Bimodal Release Tablets) for Acute Gastroenteritis.” NCT02246439
1

BEKINDA (Ondansetron 12 mg Bimodal Release Tablets)” NCT02757105

Known as Demorem ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as Desmethylondansetron ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as EUR-1025 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01036854
Known as GR 38032F ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as GR-38032 ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as GR-C507/75 ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as NSC-665799 ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as NSC-757870 ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as Odansetron hydrochloride ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as OND “The combination of dexamethasone (DEX), ondansetron (OND) and droperidol (DRO) is efficacious in preventing postoperative nausea and vomiting in adults, but has not been well...” PMID 28505233 Jun 2017
Known as Ond-PR1 “Single oral dose of 8 mg of ondansetron pulsatile-release formulation 1 (Ond-PR1)” NCT01290276
Known as Ond-PR2 “Single oral dose of 8 mg ondansetron pulsatile-release formulation 2 (Ond-PR2)” NCT01290276
Known as Ondalenz “oral ondansetron in the form of an oral soluble film 4 mg strip (Ondalenz, 4 mg orodispersible films of Nerhadou International Co.)” NCT07088601
5

“Pediatric patients will receive ondansetron lozenge 4 mg (Ondalenz ©), 2 hours before surgery as a study group.” NCT06423820

“Patients will receive ondansetron lozenge 4 mg (Ondalenz ©), 2 hours before surgery.” NCT07489742

“Patients will receive ondansetron lozenge 4 mg (Ondalenz ©), 2 hours before surgery.” NCT06423807

“Patients will receive ondansetron lozenge 4 mg (Ondalenz ©), 2 hours before surgery.” NCT06254131

“Patients will receive ondansetron lozenge 4 mg (Ondalenz ©), 2 hours before surgery.” NCT07511491

Known as Ondansetron (as hydrochloride) ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as Ondansetron (Zofran) Ondansetron (Zofran)NCT00781768
1

ondansetron (Zofran)NCT02724033

Known as Ondansetron Accord “Ondansetron (Ondansetron Accord 2mg/ml, 2 ml solution, Accord Healthcare Limited, Great Britain) in a dose of 4 mg will be administered intravenously” NCT06609993
Known as Ondansetron HCl Ondansetron HCl 8 mg OD Tablet (test) dosed in first period followed by Zofran® 8 mg ODT (reference) dosed in second period” NCT00934180
2

Ondansetron HCl 24 mg Tablets (Sandoz, Inc.)” NCT00947128

Ondansetron HCl 24 mg Tablets (Sandoz, Inc.)” NCT00946387

Known as ondansetron hydrochloride ondansetron hydrochloride(8mg, i.v. day 1-day 3)” NCT04536558
3

“Drug: Ondansetron HydrochlorideNCT02953210

“IV ondansetron hydrochlorideNCT00431236

NCT00429702

Known as Ondansetron hydrochloride dihydrate ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as Ondansetron hydrochloride hydrate ChEMBL registry synonym — accepted as the source's own label CHEMBL46
Known as Ondansetron hydrochloride preservative free ChEMBL registry synonym — accepted as the source's own label CHEMBL46