drugset / Trial / NCT03572829
Aprepitant for Nause and Vomiting Induced by Chemoradiotherapy in HNSCC
NaSingle-groupOpen-labelTreatment
Summary
To evaluate the safety and efficacy of aprepitant combined with ondansetron and dexamethasone to prevent nausea and vomiting induced by Intensity-modulated Radiotherapy (IMRT) cisplatin-chemotherapy regimen in locally advanced squamous cell carcinoma of head and neck
Timeline
- Start
- 2018-03-01
- Primary completion
- 2020-01-09
- Completion
- 2020-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aprepitant | Other / unclassified | 80 mg | Oral |
| Subject | Dexamethasone | Small molecule | 8 mg | Oral |
| Subject | Ondansetron | Other / unclassified | 8 mg | Oral |