drugset / Trial / NCT03833999
Mode of Action of Ondansetron, a 5-HT Receptor 3 Antagonist, in Lactulose Induced Diarrhoea
RandomizedCrossoverDouble-blindBasic science
Summary
This is a double-blind, two period, two treatment crossover trial of ondansetron verses placebo studying the effects of ondansetron in the small and large bowel, specifically its effects on the amount of water in the gut, measured by MRI.
Timeline
- Start
- 2018-10-16
- Primary completion
- 2019-06-27
- Completion
- 2019-06-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ondansetron | Other / unclassified | 8 mg | Oral |
| Background | Lactulose | Other / unclassified | 20 ml | — |