drugset / Trial / NCT07310563

A Trial to Evaluate Interactions Between Antiemetic Medication and AMG 133 in Participants Living With Overweight or Obesity

NCT07310563

Phase 1 Completed 59 enrolled Amgen
RandomizedParallel-groupOpen-labelBasic science

Summary

The primary objective of this trial is to evaluate the pharmacokinetics (PK) of AMG 133 administered alone and in combination with an antiemetic medication, ondansetron, in participants living with overweight or obesity.

Timeline

Start
2024-12-10
Primary completion
2025-05-09
Completion
2025-05-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Maridebart Cafraglutide Unknown 70 mg Subcutaneous
Subject Maridebart Cafraglutide Unknown 350 mg Subcutaneous
Subject Ondansetron Other / unclassified 8 mg Oral

Indications