drugset / Trial / NCT05342818
Evaluating Neostigmine Effect on Reducing Gastric Residual Volume as Compared With Metoclopramide and Ondansetron
RandomizedParallel-groupTriple-blindPrevention
Summary
One big problem in mechanically ventilated ICU patients is delayed gastric emptying. Delayed gastric emptying in these patients, causes intolerance and high gastric residual volume (GRV) that can lead to abdominal distention, vomiting, increased aspiration risk and consequently increased the length of hospital stay. In this study, investigators will evaluate Neostigmine's effect in reducing GRV in mechanically ventilated patients and compare its effect with metoclopramide and Ondansetron .
Timeline
- Start
- 2022-04-15
- Primary completion
- 2022-07-30
- Completion
- 2022-10-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metoclopramide | Small molecule | 10 mg | — |
| Subject | Neostigmine | Other / unclassified | 2.5 mg | Intravenous |
| Subject | Ondansetron | Other / unclassified | 8 mg | Intravenous |