drugset / Trial / NCT03503292

Pharmacogenomics and Post-Operative Nausea and Vomiting

NCT03503292

Phase 4 Completed 92 enrolled Mayo Clinic
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The Researchers overall goal is to evaluate the benefit and utility of preemptive genotypic data to guide post-operative nausea and vomiting treatment in the bariatric surgical population. The hypothesis is that using genotypic variation in CYP2D6 to select the appropriate 5HT3 serotonin receptor antagonist to treat PONV will decrease rates of PONV in the bariatric surgical population.

Timeline

Start
2018-05-02
Primary completion
2019-12-30
Completion
2019-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Granisetron Other / unclassified 1 mg Intravenous
Subject Ondansetron Other / unclassified 4 mg Intravenous

Indications

No indication recorded.