drugset / Trial / NCT05127876
Ephedrine Versus Ondansetron During Cesarean Delivery
RandomizedParallel-groupQuadruple-blindPrevention
Summary
More than 30% of the patients receiving spinal anesthesia develop hypotension. Hypotension developed during cesarean section (C/S) under spinal anesthesia may jeopardize uteroplacental circulation leading to fetal compromise and even fetal death. The effect of prophylactic ondansetron on blood pressure after spinal anesthesia has not been compared in a clinical trial with that of a vasoconstrictor. The investigators will compare ephedrine and ondansetron for the prevention of maternal hypotension after spinal anesthesia for elective cesarean delivery.
Timeline
- Start
- 2022-01-10
- Primary completion
- 2022-03-01
- Completion
- 2022-03-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ephedrine | Small molecule | 10 mg | Intravenous |
| Subject | Ondansetron | Other / unclassified | 4 mg | Intravenous |
| Subject | Ondansetron | Other / unclassified | 8 mg | Intravenous |
Indications
No indication recorded.