drugset / Trial / NCT00285051

Comparison of Delta-8-THC to Ondansetron in the Prevention of Acute Nausea From Moderately Emetogenic Chemotherapy

NCT00285051

RandomizedCrossoverTriple-blindTreatment

Summary

Patients will be treated for 2 consecutive chemo cycles with the study drug for one and placebo for the other. In addition, patients will receive an injection before the chemo, either ondansetron (if receiving placebo inhalation) or normal saline) if receiving active study drug. They will take study medication for 3 days, 4 times daily and fill out VAS scores before and after doses. Patients will be given rescue medication with each dose.

Timeline

Start
2005-11
Primary completion
2009-02
Completion
2009-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Delta-8-Tetrahydrocannabinol Other / unclassified 300 ug Inhaled
Subject Delta-8-Tetrahydrocannabinol Other / unclassified 600 ug Inhaled
Subject Ondansetron Other / unclassified Intravenous

Indications