drugset / Trial / NCT05590936
Dimenydrinate vs Ondansetron for PONV (DONV)
RandomizedParallel-groupTriple-blindPrevention
Summary
This study will investigate the impact of dimenydrinate (H1-receptor antagonist) versus ondansetron (HT3-receptor antagonist) in postoperative nausea and vomiting, in surgery-related preoperative stress and in the incidence of postoperative complications that could lengthen the LOS in PACU and/or the overall LOS.
Timeline
- Start
- 2018-01-01
- Primary completion
- 2022-12-07
- Completion
- 2022-12-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dimenhydrinate | Small molecule | 50 mg | Oral |
| Subject | Ondansetron | Other / unclassified | 4 mg | Intravenous |
Indications
No indication recorded.