drugset / Trial / NCT06175806
Granisetron Versus Ondansetron for Nausea and Vomiting in Pediatric Age Group
RandomizedParallel-groupOpen-labelTreatment
Summary
The current clinical trial will include 160 children who will be presented with vomiting to the Outpatient Department of the Children's Hospital, Faculty of Medicine, Ain Shams University. Participants will be assigned randomly to receive either a dispersible film Ondansetron or oral Granisetron. After initial assessment, both groups will be followed up after 6 and 48 hours to check the frequency of vomiting, diarrhea, fever, headache as well as the return of appetite and the need for further treatment. The impact of nausea and vomiting on patients' daily lives will be assessed using a modified version of the Functional Living Index-Emesis (FLIE).
Timeline
- Start
- 2023-09-10
- Primary completion
- 2023-11-11
- Completion
- 2023-11-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Granisetron | Other / unclassified | 40 ug/kg | Oral |
| Subject | Ondansetron | Other / unclassified | 4 mg | Oral |
| Subject | Ondansetron | Other / unclassified | 8 mg | Oral |
Indications
No indication recorded.