drugset / Trial / NCT01759706
Safety and Feasibility Study of Enhanced Recovery in Pancreaticoduodenectomy
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the adherence to an enhanced recovery after surgery (ERAS) pathway and the impact of the ERAS protocol on postoperative short-term outcome in patients undergoing pancreaticoduodenectomy (PD).
Timeline
- Start
- 2010-10
- Primary completion
- 2012-12
- Completion
- 2013-01
Publications
- Background Balzano G, Zerbi A, Braga M, Rocchetti S, Beneduce AA, Di Carlo V. Fast-track recovery programme after pancreatico- duodenectomy reduces delayed gastric emptying. Br J Surg. 2008 Nov;95(11):1387-93. doi: 10.1002/bjs.6324.
- Background Lassen K, Coolsen MM, Slim K, Carli F, de Aguilar-Nascimento JE, Schafer M, Parks RW, Fearon KC, Lobo DN, Demartines N, Braga M, Ljungqvist O, Dejong CH; Enhanced Recovery After Surgery (ERAS) Society, for Perioperative Care; European Society for Clinical Nutrition and Metabolism (ESPEN); International Association for Surgical Metabolism and Nutrition (IASMEN). Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. World J Surg. 2013 Feb;37(2):240-58. doi: 10.1007/s00268-012-1771-1. No abstract available.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | — | — |
| Comparator | Diazepam | Small molecule | — | — |
| Subject | Ondansetron | Other / unclassified | — | — |
| Comparator | sodium phosphate | Unknown | — | Oral |
| Background | Ropivacaine | Other / unclassified | 0.2 % | Other |
| Background | Sufentanil | Other / unclassified | 0.5 ug/ml | Other |