drugset / Trial / NCT03859102

Enhanced Recovery After Cardiac Surgery

NCT03859102

Non-randomizedSequentialOpen-labelTreatment

Summary

Enhanced Recovery Protocols (ERPs or bundles) have been established in many surgical specialties (such as colon cancer and orthopaedic joint surgeries) for several years in hospitals worldwide. The principles of Enhanced Recovery Protocols are those of early mobilization and restoration of normal function as soon as possible after surgery. These principles are achieved by use of alternate pain control regimens and removing invasive lines and drains as soon as possible. The benefits of ERPs are improved patient experience, earlier return to normal function and reduced length of stay. Enhanced recovery protocols for cardiac surgery have been published by the Enhanced Recovery After Cardiac Surgery Society. The current study will investigate whether it is possible to utilise ERP bundles in the population of cardiac surgery patients at James Cook Hospital, with a view to rolling out a full ERP service. Secondary study outcomes will be patient-centred, including; pain scores, nausea and vomiting rates and time taken to return to normal function.

Timeline

Start
2018-12-17
Primary completion
2019-10-01
Completion
2019-11-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 1 g Intravenous
Subject Bupivacaine Other / unclassified 1 mg/kg Other
Subject Bupivacaine Other / unclassified 2 mg/kg Other
Subject Dexamethasone Small molecule 8 mg Intravenous
Subject Gabapentin Small molecule 300 mg Oral
Subject Lansoprazole Other / unclassified 30 mg Oral
Subject Magnesium Sulfate Other / unclassified 50 mg/kg Intravenous
Subject Ondansetron Other / unclassified 4 mg Intravenous