drugset / Trial / NCT00183222
Effectiveness of Naltrexone and/or Ondansetron to Reduce Craving for Alcohol and Drinking
Phase 2
Completed
160 enrolled
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
RandomizedFactorialDouble-blindTreatment
Summary
The purpose of this study is to determine whether naltrexone (an opiate blocking agent approved for the treatment of alcohol dependence), ondansetron a serotonin 3 antagonist medication approved to treat nausea) or their combination are effective in the reduction of alcohol craving and drinking compared to placebo.
Timeline
- Start
- 2005-05
- Primary completion
- —
- Completion
- 2005-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naltrexone | Small molecule | 50 mg | — |
| Subject | Ondansetron | Other / unclassified | 0.25 mg | — |