drugset / Trial / NCT04443946

Different Anesthesia Maintain Protocol Effect the Outcome of the Patients

NCT04443946

Phase 4 Completed 50 enrolled China International Neuroscience Institution
RandomizedParallel-groupTriple-blindTreatment

Summary

This prospective open-label randomized study, patients were having elective urological surgery scheduled to last longer than 1 h under necessitating general anesthesia.Group-P: (Propofol group): 3 mg kg-1 min-1 propofol was pumped continuously after endotracheal intubation. Group-PAS: (Propofol and after 20 min adding Sevoflurane group): 3 mg kg-1 min-1 propofol were pumped continuously and add 1% end-tidal sevoflurane 20 minutes after endotracheal intubation. Group-PS: (Propofol and Sevoflurane group): 3 mg kg-1 min-1 propofol were continuously pumped after endotracheal intubation, and 1% sevoflurane was inhaled continuously at the same time. Group-S: (Sevoflurane group): 1% sevoflurane continued to maintain anesthesia after endotracheal intubation. Group-PSu: (Propofol and Sufentanil group): 3 mg kg-1 min-1 propofol, 0.01 μ g kg-1 min-1 sufentanil were pumped continuously at maintain phase

Timeline

Start
2020-06-25
Primary completion
2020-08-05
Completion
2020-08-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Propofol Small molecule 2.5 mg/kg
Subject Propofol Small molecule 5 mg/kg
Subject Sevoflurane Other / unclassified 1 % Inhaled
Subject Sevoflurane Other / unclassified 2 % Inhaled
Subject Sufentanil Other / unclassified 0.01 ug/kg

Indications

No indication recorded.