drugset / Trial / NCT07510217
ERAS Approach for Post-Craniotomy Headache and Psychological Recovery
RandomizedParallel-groupDouble-blindTreatment
Summary
This randomized multicenter study involves patients undergoing intracranial surgeries (Population) to evaluate whether a perioperative analgesia protocol including scalp block (SB) with dexmedetomidine (DEX) infusion (Intervention) reduces the incidence and severity of post-craniotomy headache (PCH) compared to standard opioid-based perioperative analgesia (Comparison). The study aims to determine if this Enhanced Recovery After Surgery (ERAS) approach mitigates postoperative pain, reduces opioid consumption, and improves psychological outcomes, including anxiety, depression, and sleep quality.
Timeline
- Start
- 2024-08-10
- Primary completion
- 2025-12-25
- Completion
- 2026-02-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 0.5 % | — |
| Comparator | Dexmedetomidine | Other / unclassified | — | — |
| Comparator | Fentanyl | Other / unclassified | — | Intravenous |
| Comparator | Sufentanil | Other / unclassified | — | Intravenous |
Indications
No indication recorded.