drugset
drugset / Trial / NCT03901716

Comparison of Sufentanil, Fentanyl and Remifentanil in Combination With Midazolam During Bronchoscopy Under Conscious Sedation

NCT03901716 ↗

Phase 4 Completed 60 enrolled Guangzhou Institute of Respiratory Disease
RandomizedParallel-groupTriple-blindOther

Summary

The best opioid for bronchoscopy is still unclear.This randomized double-blind prospective study was conducted on a total of 60 patients who were randomly allocated into 3 groups: Group S received sufentanil 0.1 mcg/kg, Group F received fentanyl 1 mcg/kg and Group R received remifentanil target-controlled infusion with effect-site target concentration of 1ng/ml. Patients in all groups received midazolam to achieve moderate levels of sedation as assessed by the Narcotrend (NT; between B1 and C2). Adverse events, patient tolerance and physician satisfaction were analized.

Timeline

Start
2019-01-15
Primary completion
2019-03-15
Completion
2019-03-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Fentanyl Other / unclassified 1 ug/kg —
Subject Remifentanil Small molecule — —
Subject Sufentanil Other / unclassified 0.1 ug/kg —
Background Midazolam Small molecule — —

Indications

No indication recorded.