drugset / Trial / NCT02604797

Analgesia Effects of Nalbuphine vs Sulfentanil

NCT02604797

Unknown 80 enrolled Fudan University
RandomizedParallel-groupDouble-blindTreatment

Summary

Cesarean section may result in great trauma and postoperative pain. Besides incision pain, uterine contraction pain is another source of postoperative pain after cesarean section. In clinical practice, a large amount of uterine contraction agent is routinely applied after cesarean section so as to promote involution of uterus and reduce postoperative hemorrhage, which also causes great uterine contraction pain. Acute pain is the risk factor of chronic pain, and may postpone the recovery from labour and influence the quality of life of parturient. Though various analgesia modules have been attempted, more than 20% parturients still experience severe postoperative pain, and pain management after cesarean section remains a challenge to anesthesiologists. This study aim to compare the effects of nalbuphine hydrochloride vs sufentanil citrate on patient-controlled intravenous analgesia after cesarean section.

Timeline

Start
2016-01
Primary completion
2017-01
Completion
2018-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Nalbuphine Small molecule 100 mg Intravenous
Subject Sufentanil Other / unclassified 100 ug Intravenous
Background Ramosetron Small molecule 0.3 mg Intravenous
Background flurbiprofen axetil Other / unclassified 50 mg Intravenous

Indications

No indication recorded.