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drugset / Trial / NCT03135795

The Epigenetic Modification in OPRM1 on Postoperative Analgesia and Side Effect Induced by Sufentanil

NCT03135795 ↗

Phase 4 Unknown 100 enrolled Huazhong University of Science and Technology
NaSingle-groupOpen-labelScreening

Summary

To explore the epigenetic mechanism of postoperative analgesia and side effect induced by μ-opioid Receptor Agonists presented with sufentanil among general population.

Timeline

Start
2017-02-06
Primary completion
2017-05-31
Completion
2017-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Sufentanil Other / unclassified 1 ug/ml Intravenous
Background Dexmedetomidine Other / unclassified 1 ug/kg Intravenous
Background Parecoxib Small molecule 40 mg Intravenous
Background Propofol Small molecule 0.3 mg/kg Intravenous
Background Propofol Small molecule 0.6 mg/kg Intravenous
Background Remifentanil Small molecule 0.1 ug/kg Intravenous
Background Remifentanil Small molecule 0.2 ug/kg Intravenous
Background Rocuronium Other / unclassified 0.6 mg/kg Intravenous
Background Sevoflurane Other / unclassified 1 % Inhaled
Background Sevoflurane Other / unclassified 2 % Inhaled

Indications

No indication recorded.