drugset / Trial / NCT06784999

Sufentanil Infusion vs Intravenous Methadone for Postoperative Analgesia Following Head and Neck Dissection With Free Flap or Rotational Reconstruction

NCT06784999

Phase 4 Recruiting 128 enrolled Indiana University
RandomizedParallel-groupDouble-blindTreatment

Summary

The main purpose of this study is to determine which type of medication, sufentanil or methadone, is better at controlling pain during and, more importantly, after surgery in patients undergoing a head and neck dissection with free flap or rotational tissue reconstruction. Prior to their operation, subjects will be randomized to receive either Sufentanil or Methadone. After surgery, research staff will obtain information about recovery and pain levels.

Timeline

Start
2025-01-10
Primary completion
2027-11-04
Completion
2027-11-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Methadone Other / unclassified 0.2 mg/kg Intravenous
Subject Sufentanil Other / unclassified 0.5 ug/kg Intravenous

Indications

No indication recorded.