drugset / Trial / NCT01026129
Efficacy of Remifentanil Compared to Lidocaine on the Incidence of Coughing During Emergence of Anesthesia
RandomizedParallel-groupDouble-blindPrevention
Summary
This study is designed to compare the effects of a bolus dose of remifentanil to a bolus dose of lidocaine given prior to the emergence of anesthesia: * on the incidence of perioperative coughing * on the time needed for the emergence of a desflurane-based anesthesia * on the incidence of sore throat after extubation. Our hypothesis is that the use of a remifentanil bolus dose given prior to emergence of a desflurane-based anesthesia will reduce the incidence of perioperative coughing from 70% to 35% compared to lidocaine.
Timeline
- Start
- 2010-04
- Primary completion
- 2010-06
- Completion
- 2010-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lidocaine | Other / unclassified | 1 mg/kg | Intravenous |
| Subject | Remifentanil | Small molecule | 0.25 ug/kg | Intravenous |
| Subject | Remifentanil | Small molecule | 0.5 ug/kg | Intravenous |
Indications
No indication recorded.