Automatic Remifentanil Administration Guided by ANI During Propofol Anesthesia

Completed 52 enrolled University Hospital, Lille

RandomizedParallel-groupSingle-blindTreatment

Summary

Prospective Randomized Monocentric Clinical Trial during propofol anesthesia. The aim of the study is to test whether the use of a medical device designed to automatically administer remifentanil during surgery based on expert rules and continuous reading of heart rate, blood pressure and the Analgesia Nociception Index results in lower overall remifentanil administration versus standard practice.

Timeline

Start: 2018-06-27
Primary completion: 2022-06-14
Completion: 2022-11-22

Publications

Results De Jonckheere J, Jeanne M, Keribedj A, Delecroix M, Logier R. Closed-loop administration of analgesic drugs based on heart rate variability analysis. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:506-509. doi: 10.1109/EMBC.2018.8512330.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Remifentanil	Small molecule	—	—
Background	Propofol	Small molecule	—	—

Indications

No indication recorded.