drugset / Trial / NCT00436345

Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)

NCT00436345

Phase 3 Terminated 39 enrolled GlaxoSmithKline
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will be a multicentre randomized, open-label, phase IIIb study. This study will evaluate two different techniques of sedation: an analgesia based regimen with remifentanil versus a conventional sedation based regimen using propofol in subjects that require mechanical ventilation for at least 2 days in the ICU. The conventional sedation based regimen will consist of propofol combined with an opioid according to routine clinical practice (morphine, fentanyl, sufentanil or other as required) . The analgesia based regimen will consist of remifentanil, with propofol added on if required.

Timeline

Start
2007-11
Primary completion
2008-08
Completion
2008-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule
Subject Remifentanil Small molecule

Indications

No indication recorded.