drugset / Trial / NCT00436345
Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will be a multicentre randomized, open-label, phase IIIb study. This study will evaluate two different techniques of sedation: an analgesia based regimen with remifentanil versus a conventional sedation based regimen using propofol in subjects that require mechanical ventilation for at least 2 days in the ICU. The conventional sedation based regimen will consist of propofol combined with an opioid according to routine clinical practice (morphine, fentanyl, sufentanil or other as required) . The analgesia based regimen will consist of remifentanil, with propofol added on if required.
Timeline
- Start
- 2007-11
- Primary completion
- 2008-08
- Completion
- 2008-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | — | — |
| Subject | Remifentanil | Small molecule | — | — |
Indications
No indication recorded.