drugset / Trial / NCT01056224
Effect of Remifentanil Boluses on Hemodynamics in Skull Pin Insertion
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Skull pin insertion during craniotomies is a brief, intensely stimulating, painful stimuli occurring during the conduct of a neurosurgical or spine anesthetic. Remifentanil is an ultra short acting opioid that has been successfully used to blunt hemodynamic responses in a wide variety of clinical scenarios. It is our intention to ascertain the optimal dose for blunting the hemodynamic response to skull pin insertion using remifentanil.
Timeline
- Start
- 2005-05
- Primary completion
- 2010-01
- Completion
- 2010-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Remifentanil | Small molecule | 1 ug/kg | — |
| Subject | Remifentanil | Small molecule | 1.25 ug/kg | — |
| Subject | Remifentanil | Small molecule | 1.5 ug/kg | — |
| Subject | Remifentanil | Small molecule | 1.75 ug/kg | — |
Indications
No indication recorded.