drugset / Trial / NCT02593942
Remifentanil Infusion Alone During the Closure Period for Early Emergence Following Craniotomy
RandomizedParallel-groupSingle-blindPrevention
Summary
Total intravenous anaesthesia using propofol and remifentanil are routinely used drugs for this purpose. The hemodynamic stability and at the same time early emergency are the main goals following neurosurgery. However there is no standard for discontinuation time for manually controlled systems today. The investigators aimed to study the effect of remifentanil infusion alone for early emergence and hemodynamic stability during the closure period in patients undergoing supratentorial craniotomy.
Timeline
- Start
- 2015-01
- Primary completion
- 2015-09
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Propofol | Small molecule | 75 ug/kg | Intravenous |
| Subject | Propofol | Small molecule | 200 ug/kg | Intravenous |
| Subject | Remifentanil | Small molecule | 0.1 ug/kg | Intravenous |
| Subject | Remifentanil | Small molecule | 0.5 ug/kg | Intravenous |