drugset / Trial / NCT02593942

Remifentanil Infusion Alone During the Closure Period for Early Emergence Following Craniotomy

NCT02593942

Phase 4 Completed 80 enrolled Yeditepe University Hospital
RandomizedParallel-groupSingle-blindPrevention

Summary

Total intravenous anaesthesia using propofol and remifentanil are routinely used drugs for this purpose. The hemodynamic stability and at the same time early emergency are the main goals following neurosurgery. However there is no standard for discontinuation time for manually controlled systems today. The investigators aimed to study the effect of remifentanil infusion alone for early emergence and hemodynamic stability during the closure period in patients undergoing supratentorial craniotomy.

Timeline

Start
2015-01
Primary completion
2015-09
Completion
2015-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Propofol Small molecule 75 ug/kg Intravenous
Subject Propofol Small molecule 200 ug/kg Intravenous
Subject Remifentanil Small molecule 0.1 ug/kg Intravenous
Subject Remifentanil Small molecule 0.5 ug/kg Intravenous

Indications