drugset
drugset / Trial / NCT03983889

Sedation Strategies for Diagnostic Bronchoscopy 2

NCT03983889 ↗

Unknown 200 enrolled Changhai Hospital Ruijin Hospital · collabShanghai Pulmonary Hospital, Shanghai, China · collabShanghai Zhongshan Hospital · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

Diagnostic bronchoscopy is an invasive procedure performed to diagnose respiratory diseases. But pain has been complained by most of the patients receiving such procedures. Sedation or anesthesia was required by both of the patients and bronchoscopists. Unfortunately, no consensus has been made upon the sedation strategies. Multiple sedation approaches have been applied, such as midazolam and fentanyl, remifentanil and propofol, dexmedetomidine and propofol. The present study was designed to compare these protocols in sedation for diagnostic bronchoscopy.

Timeline

Start
2019-06-17
Primary completion
2019-11-30
Completion
2019-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.5 ug/kg Intravenous
Subject Dexmedetomidine Other / unclassified 0.7 ug/kg Intravenous
Subject Fentanyl Other / unclassified 1 ug/kg Intravenous
Subject Propofol Small molecule 1 ng/ml Intravenous
Subject Propofol Small molecule 2 ng/ml Intravenous
Subject Remifentanil Small molecule 2 ng/ml Intravenous
Subject Remifentanil Small molecule 2.5 ng/ml Intravenous
Background Midazolam Small molecule 0.03 mg/kg Intravenous

Indications

No indication recorded.