drugset / Trial / NCT02988050
Conscious Sedation for Epilepsy Surgery
RandomizedParallel-groupDouble-blindOther
Summary
Sixty patients were randomly allocated into two groups, group PD and group PR, thirty patients in each group. Patients in PD group received propofol and dexmedetomidine intravenous infusion and patients in PR group received propofol and remifentanil intravenous infusion. Sedation score and patients' satisfaction, surgeon satisfaction, heart rate, mean arterial blood pressure, oxygen saturation, and side effects such as respiratory depression, nausea, vomiting, airway obstruction, and oxygen desaturation were recorded.
Timeline
- Start
- 2013-08
- Primary completion
- 2016-02
- Completion
- 2016-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 0.2 ug/kg | Intravenous |
| Subject | Propofol | Small molecule | 50 ug/kg | Intravenous |
| Subject | Remifentanil | Small molecule | 0.1 ug/kg | Intravenous |
| Background | Bupivacaine | Other / unclassified | 3 mg/kg | Other |
| Background | Epinephrine | Other / unclassified | — | Other |
| Background | Lidocaine | Other / unclassified | 4.5 mg/kg | Other |